Medical Surge Neoplasm Flashcards

1
Q

these cells develop when normal cells mutate into abnormal cells that grow uncontrollably and spread within the body

A

cancer cells

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2
Q

study of cancer; physician who specialized in caring for patients with cancer

A

oncology

oncologist

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3
Q

how many years after damage to DNA can it take for cancer to appear

A

10-20 year

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4
Q

The most frequent cancers are

A

Skin and breast

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5
Q

which cancer is most common for men only

A

prostate

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6
Q

what cancer is 2nd and 3rd most common in men and women

A

lung and colorectal

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7
Q

any changes or disruption in a gene that can produce an abnormal cell may become

A

cancerous

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8
Q

a mass of abnormal cells that grows independently of its surrounding structure and have no physiologic purpose is

A

Neoplasm / tumor
Neo = new
plasm = tissue

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9
Q

Their ___ is based on potential to damage the body and their growth characteristics
benign or malignant

A

classification

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10
Q

The development of malignancies involve complex interactions of __, __ and __ factors

A

genetic, biologic, environmental

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11
Q

localized growths with cell defined borders (encapsulated), that are slow growing, easily removed; low in incidence recurrence and can be destructive to surrounding tissue and obstruct function of organs is a

A

benign tumor

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12
Q

grows aggressively, has irregular shape and cut through surrounding tissues, causes bleeding, inflammation and necrosis, it can recur after surgical removal and treatment and can travel through blood or lymph is a

A

malignant tumor

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13
Q

suppression of the ___ is a major factor in establishment of metastatic lesions

A

immune system

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14
Q

__% of cancers have metastasized by the time of diagnosis

A

50

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15
Q

Cancer cells invade blood vessels, gaining access into the ___. Once in the blood most cancerous cells are destroyed by the ___; however even one ___ cell can move out the blood into the tissue. Once in the new site, the new malignant cells multiply and establish a ___ (secondary) ___.

A
circulation 
immune system
undetected 
metastatic 
tumor
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16
Q

Cancer causing agents, process in which normal cells are transformed into cancer cells,
cancer begins with transformation of a single normally functioning cell inept a cancer cell

A

carcinogenesis

17
Q

genes capable of promoting uncontrolled cell growth which are normally repressed
invading viruses may switch on a cells oncogenesis, causing the cell to replicate faster
normally inhibitory factors that prevent uncontrolled cell growth are suppressed, this allows the transformed cell to develop into a tumor that invades another body tissue

A

Oncogenes

18
Q

Viruses
Hep B = Liver cancer
HIV = kaposi sarcoma and lymphoma
HPV = melanoma, cervical, penile and laryngeal

A

Carcinogens

19
Q
chemotherapy = 
recreational drug use = 
hormones (estrogen) = 
are related changes =
anabolic steroids =
A
damage to normal cells = new malignancies 
suppress the immune system 
cervical, breast, & endometrial cancers 
< testosterone = prostate cancer 
tumor development
20
Q
tobacco 
pesticides 
wood and leather dust 
paints
foods-
A

chemicals

- carcinogens added during preparation or preservatives (pickled, salted foods)

21
Q

excessive exposure to radiation

A

increases rates of cancer

22
Q

uncontrolled risk factor

age:
gender:
heredity:
Poverty:

A

75% in > 55; postmenopausal on hormone replacement = breast and uterine cancer
Women: breast/thyroid more common; Men: bladder and prostate
breast, colorectal, lung and prostate
inadequate access to health care for early detection; lifestyle risks = diet, stress