Medical Considerations in Periodontal Therapy Flashcards
what are cardiac conditions that have a antibiotic prophylaxis indication?
-prosthetic cardiac valve
-previous/relapse/recurrent infective endocarditis
-congential heart disease
-cardiac transplant (with cardiac valvulopathy
pt is already taking a short course of oral antibiotic. does the pt still need to take loading dose of antibiotic prophylaxis prior to dental tx?
YES
the antibiotic blood levels must be high to protect the pt from infective endocarditis or wait 10 days after finishing the antibiotic regimen to schedule dental tx. use normal AP regimen
what goes into a medical consultation letter?
1) Define patient’s dental problem, tx plan
2) Supply medical condition of concern
3) List of questions to be answered by physician
what changes will you see in regards to the periodontium and puberty
-Increased prevalence gingivitis
-Increased Prevotella intermedia
-Periodontal tissues have exaggerated response to local factors
what is the occurrence rate of pyogenic granulomas?
0.2-9.6%
when would you excise a pyogenic granuloma?
2nd trimester
T/F perio in a pregnant mother plays into having a baby with pre term low birth weight
True
are radiographs ok during pregnancy?
when indicated for diagnosis, yes
what should you avoid with positioning during tx of pregnant mothers?
avoid supine hypotensive syndrome
sit them in a semi-supine position
what is the amount of drugs excreted into the breast milk?
usually 1-2% of dose
what is the recommendation for breastfeeding mothers and medications?
mother should take prescribed drugs after breastfeeding and avoid nursing for ≥4 hours
T/F osteopenia/osteoporosis is assoc. with menopause
true
Estrogen Deficiency and Osteopenia/Osteoporosis associated with Increased:
-Attachment loss
-Crestal bone density loss
-Enhanced attachment loss and bone loss when combined with smoking
what will bisphophonate therapy do for the oral cavity?
-Diminished osteoclast activity
-Bisphosphonate-related osteonecrosis of the jaws
where is Medication-related Osteonecrosis of the Jaws more likely to happen?
the mandible (75%)
what bisphonates are taken for osteoporosis/osteopenia
Fosamax ® (Alendronate)
Actonel ® (Risedronate)
Boniva ® (Ibandronate)
Reclast ® (Zoledronate)
what iv bisphophonates are taken for bone cancer?
-Zometa ® (Zoledronate)
-Aredia ® (Pamidronate injection)
what are other drugs related to osteonecrosis of the jaws
-prolia (denosumab)
-xgeva (denosumab)
what is the mechanism of action for denosumab
-binds to inhibits RANKL
-inhibits maturation of osteoclasts
-mimics action of osteoprotegerin
what is the ARONJ risk for oral bisphosphonates?
0.02-0.04%
ARONJ risk for IV bisphosphonates for cancer?
<5%
ARONJ risk with Denosumab?
0.3%