Medical and Pharmacological Mgmt of CVD Flashcards
Defibrillation occurs with what two heart problems? Is the heart beating before a person needs to be defibrillated?
Ventricular Tachycardia and Ventricular Fibrillation; no the heart is not beating before defibrillation
Contrast thrombolytic vs anti-thrombolytic therapies.
Thrombolytic: dissolves clot; 1st line with acute MI (within 4-6 hrs); includes streptokinase, lanoteplase, reteplase, staphylokinase.
Anti-Thrombolytic: Prevents any more clotting; given AFTER thrombolytics; includes aspirin, warfarin, heparin- injectable only!
What are the other meds associated with emergency management?
- Cholesterol/Lipid Mgmt: Statins
- Anti-Coagulants: Plavix and Coumadin
- Diuretics: Lasix, pulls extra fluid from CHF
- ACE Inhibitors: Decrease BP
- Beta Blocker: block epin. and keep slow HR
- Ca Channel Blocker: decrease vasospasm
- Cardiac Glycosides: Increase force of contraction (Digoxin)
- Ant-arrhythmias
- Nitrates: Decrease angina
Name the 5 classes of anti-arrhythmias, what they effect, and drugs include in each class.
Class I: Affects sodium- lidocaine and procanamide
Class II: Anti-sympathetics- most beta blockers -alol
Class III: Affects Potassium- Amiodarne and abutilide
Class IV: Affects calcium at AV node- verapamil
Class V: Unknown- Adenosin & Digoxin
CABGs include what two kinds of grafts?
- Saphenous vein: 81% patency at 10 yrs, longer with 2 veins to supply from, 10 yrs post= 44% have atherosclerosis
- Internal mammary artery: 96% patency at 10 years, atherosclerosis rare, short and only 1 to supply from
What method does the surgeon use for a CABG?
Anastomose to aortic root and create direct revascularization
– IMA to site distal to lesion
Give the 3 criteria needed for selection of patients for CABG. How many of these are needed to be considered?
1) 2 vessels with left ventricular dysfunction
2) Unstable angina not responding to meds
3) Emergency after an MI
–Only need one of these criteria
What are some of the post-op complications from a CABG?
Bleeding, Altered BP, cardiac arrhythmias, renal dysfucntion, infection, fluid & electrolyte imbalance, hemodynamic instability, pulmonary dysfunction, neurological events, blood clots
Is there a direct relationship between age and mortality after a CABG?
Yes, the older a patient is the higher their likelihood of death post CABG
What is a common complication of a bypass with older patients?
Stroke
Give the name of the surgical procedure that inflates a balloon in a stenotic area for 1-3 minutes at 60-80 psi.
Percutaneous Transluminal Coronary Angioplasty (PTCA)
How often does restenosis occur within patients who have a PTCA?
25-50%
T/F: According to one study there was a significant difference 4 years after between pts who had an angioplasty after an MI vs. a patient who just had meds
False; study found that there was not a difference
What can increase the long term patency of a PTCA?
A stint
What is the criteria for a PTCA? Give the mortality rate after.
Criteria: Single vessel disease
Mortality: ~1% acute complications; ~6-7% after 2-3 years.