MedChem Flashcards
1
Q
What is the most commonly used alkylating agent?
A
Cyclophosphamide - it is non-toxic prodrug which is orally active
2
Q
What is the by-product from the activation of alkylating agents?
A
Acrolein which is associated with toxicity
3
Q
What is the most toxic anticancer drug?
A
Mitocycin
4
Q
What kind of drugs are anthracyclines?
A
They are intercalating agents
