Medbear Uro Flashcards
Points of constriction in ureter?
Pelvic - Ureteric Junction
Pelvic Brim near bifurcation of common iliac arteries
Vesico-ureteric junction - entry to bladder
Types of ureter calculi?
Calcium Oxalate - 75%
Calcium phosphate - 10%
Struvite - 5~10%
Urate stones 5% Radiolucent
Cystine
Xanthine Radiolucent
Why is calcium oxalate stone significant (besides being 75%)
It causes symptoms when comparatively small owing to sharp surface
Which stones are caused by acidic urine
urate stones. The rest all alkaline urine.
Pain of calculi?
Pain - typically begins in early morning and intensifies over 15-30min
Develops in outbursts and related to movement of stones in ureter
Presentation of calculi?
Obstruction
Ulceration - haematuria
Chronic infection
Where can stones be?
kidneys
Ureter
Bladder
Are renal stones symptomatic
Mostly no, unless stone is lodged in PUJ causing hydronephrosis and subsequent infection -> pyonephrosis
Chracteristics of ureteric stones?
Even small stones cause severe symptoms
Severe intermittent loin-to-groin pain
Haematuria - 95%
Upper UTI
VUJ stone cause frequency, urgency, dysuria
What kind of diet to raise risk of stones?
High protein and sodium intake.
Predisposing conditions for stone formation?
Crohn’s
Gout
Renal Tubular Acidosis - Type 1, distal
Hyper PTH
Metastatic cancer, paraneoplastic syndrome
How to test for pyelonephritis on PE?
Positive renal punch (possibly)
PE is often unremarkable for stones
Yeaa
In PE, symptoms are often out of proportion to signs. What can be seen?
No guarding, no rebound
What does nitrite in urine mean?
it means UTI. Can be due to nitrite producing organisms like E. Coli, Klebsiella, Proteus
Principles of urolithiasis therapy?
Pain control
Treat any suspected UTI
Allow for spontaneous passage of stones OR active stone removal
Principles for Kidney stone removal?
Kidney stones often asymptomatic. Treat pre-emptively if u see any complications.
Observe if <5mm and monitor for growth. Treat if >7mm
Principles for ureteric stone removal?
Always symptomatic. Hence allow trial of passage if <7mm. Otherwise treat.
3 phases of CT Urogram?
Non-contrast phase for detection of stones
Renal parenchymal phase for detection of tumours
Excretory/delayed phase
Who is CT Urogram recommended for?
Patients with unexplained persistent gross haematuria
What is cystoscopy used for?
Gold Standard for evaluating lower urinary tract.
Can detect small bladder tumours as IVU may not detect tumours <1cm.
Biopsy can be taken together
Renal Cell Carcinoma etiology?
Mostly sporadic.
Higher rates seen in VHL disease and tuberous sclerosis complex.
Highest risk factor for RCC?
Smoking!!
2nd = prior kidney irradiation.
Family hx impt as well
Spread of RCC?
Infiltrate locally or by haematogenous spread
Benign Differentials for RCC?
Angiomyolipoma
Renal Cyst
Renal adenoma / abscess
Pyelonephritis
Renal oncocytoma
Bosniak Classification of renal cysts
1 - simple cyst
2 - minimally complex
2F - Minimally complex, need follow up
3 - Indeterminate
4 - Clearly malignant
Triad of RCC?
Painless haematuria
Mass in flank
Flank Pain
How does mass feel in RCC?
Firm, homogenous, non-tender.
Moves with respiration
Paraneoplastic syndromes of RCC?
Hypertension - renin overproduction
Stauffer Syndrome -> ALP elevated
Hypercalcaemia
Cushings Syndrome
Androgen imbalance - Gonadotropin release
Polycythaemia - EPO prod by tumour
can have hypoNa due to renin too