Med Surg Focused Review Flashcards
RBC (Normal Range, Causes of Increased or Decreased Levels)
Females: 4.2 to 5.4 million/ul
Males: 4.7 to 6.1 million/ul
Elevated level: erythrocytosis, polycythemia vera, severe dehydration
Decreased level: anemia, hemorrhage, kidney disease
WBC (Normal Range, Causes of Increased or Decreased Levels)
5,000 to 10,000/mm3
Elevated level: infection, inflammation.
Decreased level: immunosuppression, autoimmune disease
MCV
Mean Corpuscular Volume
80 to 95 fl
Elevated level: macrocytic (large) rBcs, megaloblastic anemia.
Decreased level microcytic (small) rBcs, iron deficiency anemia
MCH
Mean Corpuscular Hgb
27 to 31 pg/cell
Elevated/decreased level: same as above for mcV (Elevated level: macrocytic (large) rBcs, megaloblastic anemia.
Decreased level microcytic (small) rBcs, iron deficiency anemia)
TIBC
Total iron-binding count
250 to 460 mcg/dl
Elevated level: iron deficiency anemia, polycythemia vera
Decreased level: malnutrition, cirrhosis, pernicious anemia
IRON
Females: 60 to 160 mcg/dl
Males: 80 to 180 mcg/dl
Elevated level: hemochromatosis, iron excess, liver disorder, or lead toxicity.
Decreased level: iron deficiency anemia, chronic blood loss, inadequate dietary intake of iron.
PLATELETS
150,000 to 400,000 mm3
Increased level: malignancy, polycythemia vera, rheumatoid arthritis.
Decreased level: enlarged spleen, hemorrhage, leukemia
HGB
Females: 12 to 16 g/dl
Males: 14 to 18 g/dl
Elderly: levels slightly decreased
Elevated level: erythrocytosis, coPD, severe dehydration
Decreased level: anemia, hemorrhage, kidney disease
HCT
Females: 37 to 47%
Males: 42 to 52%
Elderly: levels slightly decreased
Elevated /decreased level: same as above for Hgb
APTT
30 to 40 seconds (1.5 to 2.5 times the control value if receiving heparin therapy)
Increased time: vitamin K deficiency, disseminated intravascular coagulation (Dic), liver disease, heparin administration
Decreased time: extensive cancer
PT
11 to 12.5 seconds, 85 to 100%, or 1:1.1 client‑control ratio
Increased time: of clotting factors ii, V, Vii, or X, liver disease, warfarin therapy, disseminated intravascular coagulation
Decreased time: vitamin K excess, pulmonary embolus, thrombophlebitis
INR
0.8 to 1.1 (desired goal of 2 to 3 on warfarin therapy) measures the mean of Pt to provide a universally recognized value.
Elevated level: warfarin therapy
Decreased level: cancer disorders
D‑DIMER
less than 0.4 mcg/ml
Positive result: disseminated intravascular coagulation, malignancy
Negative result: can rule out pulmonary embolus or deep vein thrombosis
FIBRINOGEN LEVELS
200 to 400 mg/dl
Elevated level: acute inflammation, acute infection, heart disease
Decreased levels: liver disease, advanced cancer, malnutrition
FIBRIN DEGRADATION PRODUCTS
less than 10 mcg/ml
Elevated level: disseminated intravascular coagulation, massive trauma resulting in fibrinolysis
Decreased level: antic