Med bridge base and spinal Flashcards
What part of the healing process is consistent between tissues and patients?
Relative percentage of total healing time in each phase of healing
- 10% - acute
- 40% - repair
- 70% - remodeling
A longer acute phase means a longer repair phase and remodeling phase
What is unique about the epithelial healing process
the coagulation phase - closing of the vessels is the first thing that needs to happen
What consideration must be made with sheath tendons
More dependent on diffusion and has area of vascularity
Bone healing has what to unique steps to its healing process
Soft callus phase - hematoma and clot transition to soft callus at 1-6 weeks, firborcartilage tissue and vascularization
hard callus has - transition to woven bone at 4-6 weeks
remodeling woven bones change to lamellar bone
What is unique to healing process of nerves
- Wallerian degernation phase - immediate to 3 days - axon distal to the injury is removed during cellular stage and muscle activity is lost
- Axonal degerneation phase - day 4 to 1mm pre day of growth - schwann cells form a scaffold for the new axon to grow down to the end of the nerve
what Seddon’s classificaiton the different types of nerve injuries
Seddon
- class I Neuropraxia - temporary interruption of nerve conduction
- class II axonotmesis - loss of nerve continuity with preservation of surround connective matrix, wallerian degeneration loss of nerve function peaking 3-4 days, restoration of nerve function 2-3 weeks post injury
- class III neurotmesis - disruption of the entire nerve structure requiring surgical innervation to repair
What are sunderland’s classification of nerve injury
- class I - same as Seddon class I
- class II - same as Seddon class II
- class III - epineuryium and perineurium are intact, endoneuryium requires repair
- class IV - only the epineurium is intact
- class V - complete transection
What MSK complication is associated with the antibiotic fluoroquinolone (cipro)
tedonopathy and tendon ruptures for up to 6 months post medication use
What are the normal levels for RBC and hemoglobin
- RBC’s men 4.32-5.72 trillion, women 3.9 to 5.0 trillion
- hemoglobin ment 13.5-17.5 grams per deciliter, women 12.0-15.5 grams deciliter
what is hematocrit and normal values
- test measures of the proportion of red blood cells in your blood
- men 39-51, women 34-46
What is the value of the creatine kinase assay
- measure of the breakdown of creatine reach tissue (muscle, cardiac or skeletal)
- normal values men 171 and women 145
- greater than 2.5-3% heart damage
- less than 2.5-3% muscle damage
- significant muscle breakdown causes the number to sky rocket (rhabdo 50K-200K range)
- neuropathic weakness will have slight increases 500-3500 range)
What are the normal levels for WBC and platelets
- WBC’s 3.5 to 12.5
- 140-400 K/uL
What are normal blood gas tests
pH 7.35-7.45
PaCo2 35-45 mmHg
bicarbonate 22-26 mmol/L
What pathologies would require a blood gas test (bag)
- heart failure
- kidney failure
- sleep disorder
- uncontrolled diabetes
- severe infections
what is a blood uria estrogen test (BUN) ordered for
- 10-20 mg/dL
- low with rhabdomyolysis, low protein diet, over hydration
- high with dehydration, kidney disease
How does immobilization impact muscles
- slow twitch (type I) are more affected
- well trained muscles less effected by immobilization
- single joint muscle more affected
- the shortened muscle with decrease while the length muscle with lengthen
- GAG loss on MTJ