mechanisms of breathing, pressures & work Flashcards

1
Q

when we inspire how much does the diaphragm change by?

A

75% change in volume

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2
Q

what muscles are used to inspire?

A

scalene & sternomastoids

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3
Q

what causes an increase in intrathoracic volume?

A

contraction of inspiratory muscles

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4
Q

what kind of process is inspiration?

A

an active process

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5
Q

describe the process of inspiration

A
  • contraction of inspiratory muscles
  • this caused a decrease in intrapleural pressure
  • lungs are pulled into more expanded position and the pressure in the airway becomes more negative so air moves in
  • at end of inspiration pressures are equal
  • recoil of lungs and chest wall can then occur
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6
Q

what is trans pulmonary pressure?

A

when the chest wall exerts a distending pressure on the pleural space, which is transmitted to the alveoli to increase its volume, lower its pressure and generate airflow inwards

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7
Q

what is compliance?

A

the static measure of lung stretchiness

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8
Q

what is the balance point of compliance?

A

functional residual capacity (FRC)

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9
Q

what are the end points of compliance?

A

total lung capacity (TLC) & residual volume (RV)

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10
Q

why do the lungs tend to collapse?

A

trans pulmonary pressure is positive from RV to TLC

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11
Q

why does the chest wall tend to spring out?

A

transthoracic pressure is negative at RV and FRC

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12
Q

what does the compliance of the lung depend on?

A

depends on how inflated the lung is or not

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13
Q

what is the difference between the compliance curves of inspiration and exhalation called?

A

hysteresis

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14
Q

is the lung less or more compliant at higher volumes?

A

lung is less compliant

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15
Q

what does loss of elastic recoil lead to?

A

the lungs become easy to inflate but difficult to exhale

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16
Q

what does increase in elastic recoil lead to?

A

becomes difficult to inflate the lungs

17
Q

what factors cause surface tension to increase?

A

emphysema and age

18
Q

what do type II alveolar cells do?

A

extract fatty acids from blood and synthesise surfactant

19
Q

why is surfactant important?

A
  • increases lung compliance because surface forces are reduced
  • promotes alveolar stability
  • prevents alveolar collapse
  • surface tension tends to suck fluid from capillaries into alveoli
20
Q

where does airway resistance originate from?

A

friction between air and mucosa

21
Q

what is airway resistance?

A

the pressure difference between the alveoli and mouth divided by the flow rate

22
Q

what is the airway resistance equation?

A

pressure 1 - pressure 2 / flow

23
Q

what is pulmonary resistance

A

tissue + airway

24
Q

what is laminar flow?

A

smooth flow, the resistance generated is proportional to the radius

25
Q

what is turbulent flow?

A

irregular, chaotic, with eddie currents, it is good for transferring heat but the resistance is high

26
Q

what is the “Reynold’s number” for?

A

it helps to predict when laminar flow converts to turbulent flow

27
Q

what factors affect airway resistance?

A
  • inflammation
  • mucus
  • bronchodilators
  • steroids
  • gas density
28
Q

what is elastic work?

A
  • decreased elasticity in restrictive diseases

- greater WOB

29
Q

what is non elastic work?

A

obstructive diseases lead to greater WOB to overcome increased airway resistance