Mechanisms of action Flashcards

1
Q

Mirtazepine

A

NA and 5HT specific antidepressant
Antagonist to 5HT2, 5HT3, H1, A1, A2, muscarinic ACh

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2
Q

Reboxetine

A

NA reuptake inhibitor

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3
Q

St John’s Wort

A

Weak MAOI, weak SNRI, potentially weak SSRI

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4
Q

Trazodone

A

Serotonin agonist and reuptake inhibitor
Blocks SERT at 5HT1A, 5HT2A, 5HT2C

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5
Q

Moclobemide

A

Reversible MAO-A inhibitor

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6
Q

Agomelatine

A

M1 & M2 agonist, 5HT2B and 5HT2C antagonist

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7
Q

Buproprion

A

NA / DA reuptake inhibitor, Nicotinic ACh antagonist

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8
Q

Naltrexone

A

Competitive mu antagonist

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9
Q

Disulfiram

A

Aldehyde dehydrogenase non-competitive antagonist

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