Mechanisms of action Flashcards
1
Q
Mirtazepine
A
NA and 5HT specific antidepressant
Antagonist to 5HT2, 5HT3, H1, A1, A2, muscarinic ACh
2
Q
Reboxetine
A
NA reuptake inhibitor
3
Q
St John’s Wort
A
Weak MAOI, weak SNRI, potentially weak SSRI
4
Q
Trazodone
A
Serotonin agonist and reuptake inhibitor
Blocks SERT at 5HT1A, 5HT2A, 5HT2C
5
Q
Moclobemide
A
Reversible MAO-A inhibitor
6
Q
Agomelatine
A
M1 & M2 agonist, 5HT2B and 5HT2C antagonist
7
Q
Buproprion
A
NA / DA reuptake inhibitor, Nicotinic ACh antagonist
8
Q
Naltrexone
A
Competitive mu antagonist
9
Q
Disulfiram
A
Aldehyde dehydrogenase non-competitive antagonist