Mechanisms/Drug Class Flashcards
What is the mechanism of action of H2 receptor antagonists?
Decrease acid secretion by inhibiting histamine binding to H2 receptors on parietal cells
cimetidine
H2 receptor antagonist
ranitidine
H2 receptor antagonist
famotidine
H2 receptor antagonist
nizatidine
H2 receptor antagonist
What is the mechanism of action of proton pump inhibitors?
Decrease acid secretion by irreversibly inhibiting H+/K+ ATPase on parietal cells
omeprazole
proton pump inhibitor
esomeprazole
proton pump inhibitor
lansoprazole
proton pump inhibitor
pantoprazole
proton pump inhibitor
rabeprazole
proton pump inhibitor
What is the mechanism of action of antacids?
Neutralize gastric acid by reacting with the aside to form water and salts
aluminum hydroxide
antacid
magnesium hydroxide
antacid
sodium bicarbonate
antacid
calcium carbonate
antacid
What is the mechanism of action of coating agents?
Coat gastric mucosa with a protective layer
sucralfate
coating agent
colloidal bismuth
coating agent
What is the mechanism of action of prostaglandins?
Reduce basal and stimulated gastric acid secretion; enhance bicarbonate secretion, mucus production, and blood flow
misoprostol
prostaglandin
What is the mechanism of action of anticholinergic agents?
Decrease acid secretion by inhibiting acetylcholine binding to muscarinic ACh receptors on parietal cells
dicyclomine
anticholinergic