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Pharmacology Chapter 46 > Mechanisms/Drug Class > Flashcards

Mechanisms/Drug Class Flashcards

1
Q

What is the mechanism of action of H2 receptor antagonists?

A

Decrease acid secretion by inhibiting histamine binding to H2 receptors on parietal cells

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2
Q

cimetidine

A

H2 receptor antagonist

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3
Q

ranitidine

A

H2 receptor antagonist

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4
Q

famotidine

A

H2 receptor antagonist

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5
Q

nizatidine

A

H2 receptor antagonist

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6
Q

What is the mechanism of action of proton pump inhibitors?

A

Decrease acid secretion by irreversibly inhibiting H+/K+ ATPase on parietal cells

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7
Q

omeprazole

A

proton pump inhibitor

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8
Q

esomeprazole

A

proton pump inhibitor

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9
Q

lansoprazole

A

proton pump inhibitor

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10
Q

pantoprazole

A

proton pump inhibitor

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11
Q

rabeprazole

A

proton pump inhibitor

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12
Q

What is the mechanism of action of antacids?

A

Neutralize gastric acid by reacting with the aside to form water and salts

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13
Q

aluminum hydroxide

A

antacid

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14
Q

magnesium hydroxide

A

antacid

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15
Q

sodium bicarbonate

A

antacid

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16
Q

calcium carbonate

A

antacid

17
Q

What is the mechanism of action of coating agents?

A

Coat gastric mucosa with a protective layer

18
Q

sucralfate

A

coating agent

19
Q

colloidal bismuth

A

coating agent

20
Q

What is the mechanism of action of prostaglandins?

A

Reduce basal and stimulated gastric acid secretion; enhance bicarbonate secretion, mucus production, and blood flow

21
Q

misoprostol

A

prostaglandin

22
Q

What is the mechanism of action of anticholinergic agents?

A

Decrease acid secretion by inhibiting acetylcholine binding to muscarinic ACh receptors on parietal cells

23
Q

dicyclomine

A

anticholinergic

Pharmacology Chapter 46 (1 decks)

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