Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology Chapter 9 > Mechanisms/Drug Class > Flashcards

Mechanisms/Drug Class Flashcards

1
Q

What is the mechanism of action of hemicholinum-3?

A

Blocks the high-affinity transporter for choline and thereby prevents the uptake of choline required for ACh synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the mechanism of action of vesamicol?

A

Blocks the ACh-H+ anti porter that is used to transport ACh into vesicles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the mechanism of action of botulinum toxin?

A

Produced by Clostridium botulinum, degrades synaptobrevin and thus prevents synaptic vesicle fusion with the axon terminal (presynaptic) membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the mechanism of action of the inhibitors of acetylcholine degradation?

A

Inhibit acetylcholinesterase by binding to the enzymes active site; this increases the conc. of endogenously released ACh in the synaptic cleft; accumulated ACh activates nearby receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

edrophonium

A

Inhibitor of acetylcholine degradation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

neostigmine

A

Inhibitor of acetylcholine degradation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

pyridostigmine

A

Inhibitor of acetylcholine degradation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

ambenoium

A

Inhibitor of acetylcholine degradation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

physostigmine

A

Inhibitor of acetylcholine degradation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

diisopropyl fluorophosphate

A

Inhibitor of acetylcholine degradation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

tacrine

A

Inhibitor of acetylcholine degradation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

donepezil

A

Inhibitor of acetylcholine degradation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

rivastigmine

A

Inhibitor of acetylcholine degradation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

galantamine

A

Inhibitor of acetylcholine degradation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

methacholine

A

Muscarinic receptor agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

carbachol

A

Muscarinic receptor agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

bethanechol

A

Muscarinic receptor agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

cevimeline

A

Muscarinic receptor agonist

19
Q

pilocarpine

A

Muscarinic receptor agonist

20
Q

What is the mechanism of action of nicotinic receptor agonists?

A

Stimulate opening of nicotinic ACh receptor channel and produce depolarization of the cell membrane; succinylcholine persists at the neuroeffector junction and activates the nicotinic receptor channels continuously, which results inactivation of voltage-gated sodium channels so that they cannot open to support further action potentials (“depolarizing blockade”)

21
Q

atropine

A

Muscarinic receptor antagonist

22
Q

scopolamine

A

Muscarinic receptor antagonist

23
Q

pirenzepine

A

Muscarinic receptor antagonist

24
Q

methscopolamine

A

Muscarinic receptor antagonist

25
Q

glycopyrrolate

A

Muscarinic receptor antagonist

26
Q

ipratropium

A

Muscarinic receptor antagonist

27
Q

tiotropium

A

Muscarinic receptor antagonist

28
Q

oxybutynin

A

Muscarinic receptor antagonist

29
Q

propantheline

A

Muscarinic receptor antagonist

30
Q

terodiline

A

Muscarinic receptor antagonist

31
Q

tolterodine

A

Muscarinic receptor antagonist

32
Q

fesoterodine

A

Muscarinic receptor antagonist

33
Q

trospium

A

Muscarinic receptor antagonist

34
Q

darifenacin

A

Muscarinic receptor antagonist

35
Q

solifenacin

A

Muscarinic receptor antagonist

36
Q

What is the mechanism of action of nicotinic receptor antagonists?

A

Selectively antagonize nicotinic receptors, thus preventing endogenous ACh binding and subsequent muscle cell depolarization (“nondepolarizing blockade”)

37
Q

pancuronium

A

Nicotinic receptor antagonist

38
Q

tubocurarine

A

Nicotinic receptor antagonist

39
Q

vecuronium

A

Nicotinic receptor antagonist

40
Q

rocuronium

A

Nicotinic receptor antagonist

41
Q

mivacurium

A

Nicotinic receptor antagonist

42
Q

trimethaphan

A

Nicotinic receptor antagonist

43
Q

mecamylamine

A

Nicotinic receptor antagonist

Pharmacology Chapter 9 (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions