Mechanisms Flashcards
conditions for SN2 reaction
strong nucleophile
conditions for E2 reactions
strong base
conditions for SN1 reaction
poor nucleophile
conditions for E1 reactions
conc. H2SO4 or conc. H2PO4
what are the 3 ways to make alcohols into good leaving groups?
Pbr3, SOCI2 w/ Py, TsCI w/ Py
alkene halogenation can be done with ______ or ______
water H2o or alcohol
alkene —-> anti addition of X. what can X2 be?
Br, CI, I
alkene halogenation with alcohol, OR/OH is added to the more ______ side
substituted
conditions for alcohol to ether
1.strong base
2. C-C-X
what reaction happens to go from an alcohol to ether
SN2
conditions for alcohol to cyclic ethers and epoxides
NaH
what mechanism happens going from an alcohol to cyclic ethers and epoxides
intramolecular Sn2
conditions for the primary and triteary cleavage of ethers
conc. HX in heat
a Sn_ happens when cleaving primary ethers
Sn2
a Sn_ happens when cleaving triterary ethers
Sn1
conditions for the addition of CI or Br to alkenes
H-X
conditions for alkene to alcohol
H20, H+ cat
conditions for alkene to ether
ROH, H+ cat
conditions for addition of H2 to alkenes
H2 Pd/C
what is the term for the addition of H2 to alkenes
hydrogenation
what product is formed with the addition of X2 to alkenes
anti product only
what are 2 ways to go from alkenes to alcohols
oxymercuration reudction and hydroboration oxidation
conditions for oxymercuration reudction
- Hg (OAc)2, H20 (oxymercuration)
- NaBH4 (reudction)
conditions for hydroboration oxidation
- BH3, THF (hydroboration)
2.H2O2, NaOH (oxidation)
oxymercuration reudction will give you what kind of product?
Mark product
hydroboration oxidation will give you what kind of product?
anti Mark product
conditions for alkene to epoxide
Br2, h2o
NaH
you can go from alkene to epoxide using what kind of acid?
peroxyacids
opening epoxides in acidic conditions
mCPBA
ROH, H+
opening epoxides in basic conditions
mCPBA
NaOR
