Mechanism Of Action Flashcards
0
Q
Barbiturate
A
Binds to GABA-A receptor sites to increase duration of chloride channel opening
1
Q
Benzodiazepine
A
Binds GABA-A receptor subunits to increase frequency Of chloride channel opening
2
Q
Inhalational anesthetics
A
Facilitate GABA mediated inhibition; block brain NMDA and ACh-N receptors
3
Q
Local anesthetics
A
Block voltage dependent Na channels reducing Na influx -> no depolarization
4
Q
Nondepolarizing neuromuscular blockade
A
Prevent action of ACh at motor endplate
5
Q
Typical antipsychotics
A
Block of D2 Receptors
6
Q
Atypical antipsychotics
A
Block of 5-HT2 receptors
7
Q
Tricyclic antidepressants
A
Block NE and 5-HT2 transporter