Mechanism of Action Flashcards

1
Q

Octreotide (Sandostatin)

A

Selective splanchnic vessel constrictor for the treatment of portal hypertension

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2
Q

Coregard

A

Nadolol
non-selective beta blocker used for prevention of portal hypertension

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3
Q

Inderal

A

Propanolol
non-selective beta blocker used for prevention of portal hypertension

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4
Q

Lactulose

A

converts ammonia produced by the intestinal bacteria to ammonium

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5
Q

Rifaximin

A

inhibits activity of urease-producing bacteria to decrease ammonia production

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6
Q

Where in the nephron does furosemide work?

A

the ascending Loop of Henle on the Na/K pump

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7
Q

Where in the nephron does Farxiga work?

A

Dapagliflozin
the proximal tubule by blocking SGLT2
**most of the Na and Ca is reabsorbed here

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8
Q

Where in the nephron does Microzide work?

A

HCTZ
Distal convoluted tubule where it inhibits Na-CL pump

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9
Q

Where in the nephron does Inspra work?

A

Eplerenone
The collecting duct is affected by ADH and aldosterone levels. Aldosterone inhibitors block aldosterone in the collecting duct from absorbing more water and Na+

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10
Q

Aluminium hydroxide

A

potent phosphate binder and block the absorption of dietary phosphate

**take prior to meal TID

HIGH RISK OF ALUMINIUM ACCUMULATION

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11
Q

Calcium Acetate

A

Phosphate binder that block absorption of dietary phosphate.

**take prior to meals TID

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12
Q

Ferric citrate

A

Al and Ca free phosphate binder to block absorption of dietary phophate

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13
Q

Lanthanum Carbonate

A

Al and Ca free phosphate binder to block absorption of dietary phophate

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14
Q

Renvela

A

Sevelamer Carbonate
no Ca or Al phosphate binder that is NOT systemically absorbed ===== you poop it out (:

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15
Q

Renagel

A

Sevelamer hydrochloride no Ca or Al phosphate binder that is NOT systemically absorbed ===== you poop it out (:

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16
Q

Calcitriol

A

Vit D analog that increase intestinal absorption of Ca to STOP the parathyroid from producing PTH that stimulates bone breakdown (hypercalcemia)

17
Q

Sensipar

A

Cinacalcet
increases the sensitivity of calcium sensing receptors on the parathyroid gland

Decreases PTH, Ca, and Phosphate

18
Q

Kayexalate

A

Sodium polyestyrene
binds to K+ in the GI tract to decrease hyperkalemia

19
Q

Albuterol for Hyperkalemia

A

Shifts K+ back intracellularly

20
Q

Calcium Gluconate for Hyperkalemia

A

Stablizes the membrane around the heart to prevent arrhythmias