Mechanism Flashcards by Nawaporn Pathom-eam | Brainscape

Q

50s ribosome synthesis

A

Macrolide(Azi- Ery- Clarithromycin)
Clindamycin
Chloramphenicol
Linezolid

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Q

30s ribosome

A

Aminoglycoside
Tetracycline

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Q

MRNA synthesis inhibits RNA poly

A

Rifampin

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Q

Inh DNA gyrase

A

Fluoroquinolones

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Q

Inh DNA integrity

A

Metronidazole
Nitrofurantoin

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Q

Folic acid pathway

A

TMP(step2)/SMX(step1) or Bactrim

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Q

Kill - Cell mb integrity

A

Daptomycin
Polymycin

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Q

Kill - Cell mb syn < de peptoglycan synthesis >

A

Vancomycin
Fosfomycin

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Q

Kill - cell mb syn < de crosslinking of PGs> B-lactam

A

PCNs
-Natural
-Antistaphylococcal
-Amino + BLI
-Antipseudomonal + BLI
Caphalosporin
Carbapenem
Monobactam

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Q

Beta lactamase inhibitors

A

Clavulanate - amoxicillin
Sulbactam - ampicillin
Tazobactam - piperacillin
Avibactam - ceftazadime

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