mechanics of breathing Flashcards
Pulmonary ventilation consists of which two phases?
- inspiration
- expiration
Define intrapulmonary pressure
- Ppul is the pressure within the alveoli
What pressure prevents the lungs from collapsing?
- Transpulmonary pressure
How is transpulmonary pressure calculated?
Intrapulmonary pressure (Ppul) - Intrapleural pressure (Pip)
List the muscles of normal respiration
- Diaphram
- intercostal muscles
Name the physical factors influencing pulmonary ventilation
- Airway resistance
- Alveolar surface tension
- Lung compliance
Name the four respiratory volumes
- tidal volume
- inspiratory reserve volume
- expiratory reserve volume
- residual volume
Define vital capacity
Vital capacity = total sum of IRV + ERV + TV
Define dead space
Amount of inspired air within the conducting zone that does not participate in gaseous exchange
Define intrapleural pressure
Pip = the pressure within the pleural cavity
Define total lung capacity
- TLC is the maximum volume of air contained in the lungs after maximum inspiratory effort
- TLC = TV + ERV + IRV + RV
Define Functional residual capacity
- FRC is the sum of Expiratory reserve volume and Reserve volume
- the volume of air remaining in the lungs after normal tidal expiration
Define minute volume
- MV is the volume of air inspired and expired in a minute
- MV = TV x RR
Define alveolar minute volume
- Alveolar ventilation rate = RR x (TV - dead space)
Define nonrespiratory air movements
Nonrespiratory air movements are voluntary or reflex actions that clear the respiratory passageway or express emotions
What respiratory group of the respiratory centre controls inspiration?
Dorsal respiratory group
Which muscles of respiration does the Dorsal respiratory group control?
- Diaphragm
- External intercostal muscles
What nerves are responsible for initiating ventilation?
- Phrenic nerves
- Intercostal nerves
Describe phase 1 of inspiration
- inspiratory muscles contract
- diaphragm moves down
- thoracic cavity expands and volume increases
Describe phase two of inspiration
- intrapulmonary pressure decreases by 1mmHg
- air flows into the lungs along the pressure gradient until Ppul = Patm
Describe phase 1 of expiration
- inspiratory muscles relax
- diaphragm rises
- thoracic cavity recoils and volume decreases
Describe phase 2 of expiration
- thoracic recoil causes an increase in intrapulmonary pressure by 1mmHg
- air flows out of the lungs down the pressure gradient until Ppul = Patm
What is the normal value for tidal volume?
500ml
True or false? Adult males and females have the same total lung capacity
False
What is the value for normal intrapleural pressure?
756mmHg
In which air passages does the greatest resistance to airflow occur?
Medium-sized bronchi
Which factors diminish compliance?
- reduced natural resiliance of lungs
- blocked small respiratory passages
- reduced surfactant production
- decreased flexibility/expandability of thoracic cage
What device is used in hospital to measure a patient’s lung volume and capacity?
A spirometer
Define Boyle’s law
At a constant temperature , the pressure of a gas varies inversely with its volume
P1V1 = P2V2
How do you calculate physiological dead space?
anatomical dead space + alveolar dead space