Measuring membrane/ channel function Flashcards
1
Q
what mechanism is used to control membrane voltage in voltage clamp?
A
negative feedback
2
Q
in a voltage clamp, what does current =?
A
current generated across membrane causing a change in membrane potential
3
Q
what does macroscopic refer to?
A
whole cell membrane
4
Q
what does microscopic refer to?
A
single channels in cell membrane
5
Q
are single channels reliable?
A
no
6
Q
if slope= chord conductance?
A
ohmic behaviour
7
Q
if slope DOES NOT = chord conductance?
A
non- ohmic behaviour- due to blockage/ reduced activation
