Measles, mumps and rubella Flashcards

1
Q

What causes measles?

A

RNA morbillivirus

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2
Q

How is measles transmitted?

A

Via respiratory droplets

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3
Q

What is the presentation of measles?

A

Rash for 3 days, fever for 1 day + cough and conjunctivitis

Prodrome period: 2-4 days; Koplik’s spots (inside of mouth), rash, high fever, swelling around eyes and photophobia

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4
Q

What is the management of measles?

A

Refer to GP
Paracetamol/Ibuprofen and fluids
Infection goes on own accord

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5
Q

It measles a notifiable disease?

A

Yes, GP has to inform goverment on each case

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6
Q

What are the complications with measles?

A
Bronchopneumonia
Acute demyelinating encephalitis
Sub-acute sclerosing panencephalitis
Ear infections - permanent loss of hearing
Diarrhoea
Vitamin A deficiency and blindness
Immunodeficiency
Miscarriage, prematurity and low birth weight
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7
Q

What causes mumps?

A

Paramyxovirus

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8
Q

What does mumps usually affect?

A

Salivary glands, pancreas, testes and ovary

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9
Q

How is mumps transmitted?

A

By saliva droplets

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10
Q

What is the presentation of mumps?

A

Swelling on one side of face (parotitis); bilateral, pain near jaw
Asymptomatic or non-specific symptoms (fever, headache, malaise)
Fever, swelling, dry mouth, discomfort
Infertility and deafness later in life

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11
Q

How is mumps diagnosed?

A

Clinical or salivary IgM

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12
Q

What is the managment for mumps?

A

Pain killers, rest and fluid

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13
Q

What are the complications with mumps?

A
Orchitis
Chills, headache, swinging temperature, backache
Swollen scrotum, usually unilateral
Meningitis or encephalitis
Oophoritis
Pancreatitis
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14
Q

What is rubella caused by?

A

Togavirus

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15
Q

What is the presentation of rubella?

A

Low grade fever, malaise, conjunctivitis, lymphadenopathy (swollen glands)
Transitory rash on face and neck

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16
Q

How is rubella transmitted?

A

Via droplets

17
Q

When are patients with rubella infectious?

A

From 1 week before rash to 4 days after rash appears

18
Q

Diagnosis of rubella?

A

clinically unreliable

Rubella-specific IgM in saliva

19
Q

What is the managment of rubella?

A

Antipyretics (paracetamol and ibuprofen)
Exclude from school
Keep away from pregnant women

20
Q

What are the complications with rubella?

A

Thrombocytopenia
Post-infectious encephalitis
Arthrtis and arthralgia (rare)

21
Q

What is congenital rubella syndrome? (CRS)

A

Maternal rubella in pregancy: (the baby develops)

  • cataracts and other eye diseases
  • deafness
  • cardiac abnormalities
  • microephaly, intelluctual disability
  • retardation of intrauterine growth
  • inflammation lesions in the brain, liver, bone, and lungs
22
Q

What is the prognosis of CRS?

A

Up to 4 weeks before conception: 40%
0-12 weeks: 50%
11-16 weeks: 20%
>16>20: deafness is main outcome

23
Q

What is the MMR vaccination?

A

Combined live vaccine given as a baby at 1 month and on starting school at afe 4-5; then immune for the rest of your life

24
Q

Who else is the MMR vaccine given to?

A

Rubella seronegative women at child bearing age
Non-immunised adults as health workers
Immigrants arriving at school after immunisation age
Conacts during a measles outbreak

25
What was the controversy with the MMR vaccine?
Dr Andrew wakefield published a paper in 1998 claiming a link between the MMR vaccine and autism or bowel disease, this has now been discredited. However, it caused a lot of people not getting the vaccine, herd immunity was therefore lost and infection rates went up. This was partly due to the media coverage
26
How did the goverment try and come back from the MMR vaccine controversy?
- Discredited the research - Local and national public health campaign to increase MMR uptake - Social media campaigns