MCQ lecture Flashcards
Which chemical substance stimulate love?
Oxytocin
What does Spanish fly/ ground up beetle swell?
Blood vessels/ vasoconstrictor
What vegetable contains androsterone?
Celery
What was the first FDA approved recombinant protein therapeutic?
Insulin
What is an antagonist?
Something that binds a receptor but doesnt activate it and prevents endogenous chemical messengers from binding.
What is an agonist?
A drug that has the same action on a receptor as an endogenous chemical.
What is an inverse agoninst?
A drug that binds to a receptor, fails to activate it and causes a drop in biological activity
What is desensitisation?
When an agonist has been bound to a receptor for a long period of time and a phosphorylation reaction occurs.
What is efficacy?
The maximum biological effect that results from a drug binding to a target
What is potency?
the amount of drug required to produce a required biological effect.
What is a reverse inhibitor?
A drug that binds to an active site and inhibits the enzyme. Inhibition decreases as substrate concentration increases.
What is an allosteric inhibitor?
A drug that inhibits an enzyme but acts at a site other than the active site.
What is pharmacokinetics?
How drugs reach their target in the body and how levels of a drug in the body are affected by various factors.
What is pharmacodynamics?
How drugs interact with the target binding site at a molecular level.
Receptors for estrogens, progestins and androgens are classified as
Ligand activated Transcription factors
