MCMP 284: Lecture 3 Flashcards
1
Q
nearly all atoms in organic molecules are _____ _____ than C
A
more electronegative
2
Q
electron effects are described with a a parameter know as
A
hammet’s sigma
3
Q
what values are additive?
A
pi values
4
Q
if you want us to modify a drug with least amount of “perturbed” what value do we look for?
A
the lowest perturbed would be smallest PI values and smallest sigma values
