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MCCQE1 > MCCQE1 > Flashcards

MCCQE1 Flashcards

1
Q

Mechanism in cervical insufficiency (Interleukin)

A

IL-8

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2
Q

Cervical insufficiency treatment

A

Progesterone or cerclage (ø benefit to combine)

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3
Q

MSAFP for in Down (T21)?

A

Decreased

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4
Q

Dates for chorionic sampling, amniocentesis

A

Chorionic: 12 wk
Amnio: 11 wk possible, optimal at 15-17 wk

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5
Q

4Ts of PPH

A

Tone (atony, 75% cases), Tissue (retained placenta), Thrombin (coagulopathy), Trauma (laceration)

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6
Q

Postcoital bleeding. R/O what?

A

Cancer until proven otherwise

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7
Q

T/F Negative Pap rules out cancer

A

False

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8
Q

Hallmark of subserous leiomyoma

A

calcifications

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9
Q

Which has most risk of ectopic pregnancy? Hx of 3 PIDs or an IUD

A

3 PIDs

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10
Q

Tamoxifen: agonist / antagonist on what?

A

More agonist on bone tissue (prevents osteoporosis)

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11
Q

Tamoxifen ↑↓ risk of endometrial cancer?

A

↑

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12
Q

Which drug associated with placental abruption?

A

Cocaine

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13
Q

PCOS ↑↓ endometrial cancer?

A

↑

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14
Q

Chancre vs chancroid, which is painful?

A

Chancroid (H. ducrei, do-cry)

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15
Q

Age at which to investigate 1° amenorrhea?

A

If 2° sex characteristics: wait until 16, if no 2° sex characteristics investigate at 14

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16
Q

Treatment for male HPV

A

Podophylline

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17
Q

NTDs, MSFAP is ↑ or ↓?

A

↑

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18
Q

BRCA1, % risk for breast cancer, ovarian cancer?

A

65% breast

40% ovary

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19
Q

BRCA1, age at which to start screening?

A

25 years

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20
Q

GDM, induce at which week? What if IDGDM?

A

GDM: 41 wk
IDGDM: 39 wk

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21
Q

2° line uterotonic after oxytocin?

A

Carboprost

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22
Q

Which management is NOT acceptable for DeQuervain Tenosynovitis?

A

Watchful Waiting

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23
Q

DDH management by age

A

0-6 mo: Pavlik Harness
6-18 mo: Closed reduction under US guidance + spica
> 18 mo: Medial approach open reduction at 2 years or if failure

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24
Q

α1-antagonist for BPH

A

Terazosin

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25
Q

5α-reductase antagonist for BPH

A

Finasteride

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26
Q

Right handed man, left knee pain. Cane in which hand and and advance with which leg?

A

CHAI

Controlateral Hand, Advance with Ipsilateral leg

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27
Q

GCS

A

Eyes 4 (spontaneous 4, command 3, pain 2, no 1)

Speech 5 (clear 5, confused 4, words 3, sounds 2, no 1)

Motor 6 (command 6, localize 5, withdraw 4, decorticate 3, decerebrate 2, no 1)

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28
Q

Nursemaid’s elbow, treatment?

A

Supination-flexion or hyperpronation

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29
Q

Echinococcus liver abcess tx?

A

Flagyl

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30
Q

Echinococcus intraluminal disease tx?

A

Paromomycine

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31
Q

Success rate of Mohs for BCC? Recurrence?

A

96% success rate, <5% recurrence

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32
Q

Osteosarcoma age

A

5-20 yr, then > 65 yr

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33
Q

Osteosarcoma vs Ewing location

A

Ewing: Diaphysis
OS: Metaphysis

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34
Q

Benign features of calcifications on mammography?

A

Large, popcorn

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35
Q

Prostate TNM

A

T1 ø palpable
T2 confined to prostate
T3 extracapsular
T4 bladder, pelvic wall or adjacent

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36
Q

Prostate Mx characteristic

A

Osteoblastic

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37
Q

MALT caused by what? Tx?

A

H. Pylori. Eradication

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38
Q

Most common esophageal cancer worldwide, US?

A

Worldwide: SCC
US: ADK

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39
Q

Esophageal SCC risk factor

A

Hot drinks, tobacco

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40
Q

Esophageal ADK risk factor

A

Barrett esophagus

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41
Q

Colorectal cancer screening

A

low risk individuals:
q1-2 FOBT
Colonoscopy q10

Low risk individuals: If > 10 polyps, or > 1 cm -> q2

High risk individuals: if 1 polyp, <1 cm -> q5
if ≥ 2 polyps, > 1 cm -> q3

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42
Q

What to resect as well in meckel?

A

Appendix

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43
Q

Acute monoarticular arthritis: (almost) always exclude what?

A

septic arthritis

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44
Q

Most common 2° effect with SSRI in med

A

Delayed ejaculation

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45
Q

Sleep changes in depression

A

↓ REM latency so ↓ duration of deep phase (restorative) sleep

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46
Q

Atypical antipsychotics, highest risk of metabolic syndrome

A

Olanzapine

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47
Q

Kawasaki severity criteria

A

HypoNa, via SIADH

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48
Q

Gold standard for pneumococcus vaccination in peds?

A

13-valent

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49
Q

Lens opacification, which enzyme?

A

Gal-1-P- uridyltransferase

50
Q

Neuroblastoma, dose what substance?

A

Vanillic acid

51
Q

Isotretinoin, what congenital anomaly?

A

Microcephaly

52
Q

Treatment for impetigo (local or generalized)

A

Mupirocin or clavulin

53
Q

Alport syndrome

A

Recurrent hematuria, SN deafness, FHx renal failure

54
Q

Down syndrome + UMN findings. R/O what?

A

Atlantoaxial instability

55
Q

Head lice treatment

A

permethrin

56
Q

Icterus at mid-abdomen, what’s the bilirubin at?

A

250

57
Q

Marfan gene

A

Fibrillin-1

58
Q

Treatment for strep throat if penicillin allergy

A

erythromycin

59
Q

NSAIDS vs Prostaglandin (which) for patent ductus arteriosus

A

NSAIDs CLOSE PDA

PGE1 keeps it OPEN

60
Q

Rubeola

A

Rougéole, measles

Koplik spots

61
Q

Rubella

A

Rubéole, german measles

Majority asymptomatic

62
Q

Bacterial tracheitis, which germ?

A

SA

63
Q

Molluscum, which virus?

A

Poxvirus

64
Q

Absence seizure, which Ψ disorder associated?

A

ADHD, inattentive type

65
Q

Pertussis treatment

A

Erythromycin (if > 1 month age)

66
Q

2 associations hepatitis & vasculitis

A

HCV - cryoglobulinemia

HBV - PAN

67
Q

Which Hb required to SEE cyanosis?

A

50

68
Q

Which Bili required to SEE icterus?

A

50

69
Q

3 germ in travellers diarrhea

A

cryptosporidium, cyclosporidium, giardia

70
Q

aSx elderly patient with ALP? R/O what?

A

Paget

71
Q

Paget, quelle complication ORL?

A

Otosclérose

72
Q

Lewy-Body Dementia (3 features)

A

Visual hallucinations, Parkinsonism, fluctuating cognition

73
Q

Frontotemporal dementia (3 features)

A

Personality & Behaviour changes, compulsions, executive dysfx

74
Q

ALS treatment

A

Riluzole

75
Q

EPO consequence

A

Worsen HTN and cause hypertensive crisis

76
Q

6 causes of erythema nodosum

A

OCP, sarcoidosis, TB, IBD, histoplasmosis, Behcet

77
Q

Febrile neutropenia Tx

A

Pip tazo

78
Q

GPA/EGPA, which ANCA?

A

GPA (Wegner) = c-ANCA

EGPA (Churg-Strauss) = p-ANCA

79
Q

Restless leg syndrome, r/o what?

A

Test iron deficiency, correct if present?

80
Q

Herpetiform dermatitis, tx?

A

Dapsone

81
Q

Flumist age?

A

2-59 years, not in pregnancy, AIDS, immunosuppressed

82
Q

Sickle cell feature on smear

A

Howell-Jolly Bodies

83
Q

Guillain-Barre, which infection most frequent?

A

Campylobacter, herpes, mycoplasma, H. influenza

84
Q

Guillain-Barre, which test for prognosis?

A

Spirometry for inspiratory force

85
Q

Which lab test to confirm abstinence?

A

Carbohydrate-deficient transferrin

86
Q

Frequent HSA complication & Tx

A

Cerebral vasospasm, Triple H therapy and CCB

87
Q

Pneumonia + Diarrhea, which infection?

A

Legionella

88
Q

HIT skin change?

A

necrosis at injection site

89
Q

Pheo treatment (order)

A

Phenoxybenzamine α-blocker first, then β-blockers to prevent severe HTN

90
Q

pH associated with struvite stones

A

High pH, proteus mirabilis

91
Q

Struvite stones prophylaxis

A

acetohydroxamic acid

92
Q

Complication of methimazole/PTU

A

Agranulocytosis

93
Q

PTU/Methimazole in pregnancy

A

1st trimester: PTU

2-3rd trimester: Keep PTU or switch to methimazole

94
Q

Cellulitis germ?

A

GAS most frequent, SA if purulent

95
Q

Vitamin to prevent hangover?

A

B6

96
Q

Thyroid cancer
Most common?
Most metastatic?

A

Most common: Papillary

Most metastatic: Hurtle ¢

97
Q

Primary biliary cholangitis, antibody? Which deficiency?

A

ADEK deficiency

Anti-Mito

98
Q

SCLC, most common paraneoplasic

A

PTHrP

99
Q

Alkaline urine infection, which germ?

A

Proteus mirabilis

100
Q

Alcoholic without smell of alcohol + convulsion r/o what?

A

DT

101
Q

Urine sediment finding in ATN?

A

Muddy brown casts

102
Q

PCP treatment, when to add corticosteroids?

A

TMP-SMX, add corticosteroids if PaO2 < 70 or Aa gradient > 35

103
Q

SJS vs TEN?

A

SJS < 10% BSA
TEN > 30% BSA
Overlap between

104
Q

Hep B vaccination series timing

A

0, 1, 6 months

105
Q

Furosemide toxicity?

A

Ototoxicity

106
Q

Jones Criteria for RAA

A
  1. Erythema marginatum
  2. S/C nodules
  3. Syndenham Chorea
  4. Carditis
  5. Arthritis
107
Q

Rash affected by ROH?

A

Rosacea

108
Q

Heinz bodies

A

G6PD

109
Q

Iron deficiency 2 associations

A

Breath holding spells

Restless leg syndrome

110
Q

Battle sign & racoon eyes associated with what?

A

Temporal bone fx

111
Q

Constitutional growth delay, bone age = ?

A

Delayed

112
Q

HPV on vaginal mucosa Tx?

A

Trichloroacetic acid

113
Q

Serotonin syndrome Tx

A

Cyproheptadine

114
Q

Vaccine with highest amount of egg

A

Yellow fever vaccine

115
Q

Varicocele management?

A

Testicular volume measurement

116
Q

Release of preformed thyroid hormone, don’t treat with what?

A

Methimazole (no pregnancy) or PTU

117
Q

Drug induced lupus

A

Hydralazine

118
Q

Rash BB following GAS infection

A

Guttate psoriasis

119
Q

Albumin sepsis ↑↓?

A

↓ acute phase reactant (negative)

120
Q

Lung abcess Tx

A

Clindamycin

MCCQE1 (1 decks)

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