Matt Neale Flashcards
1
Q
Pseudoautosomal
A
Only part of X and Y chromosomes that pair and recombine
2
Q
Synaptonemal complex
A
Zips up homologues via transverse filaments
Degraded prior to chromosome segregation
Possibly helps to stabilise chiasma
Scp3: central element, staining allows observation of paired chromosomes
3
Q
Stepwise removal of cohesin
A
- Arm cohesin removed at anaphase 1
- Remove centromeric cohesin at anaphase 2
Phosphatase in shugoshin prevents rec8 in cohesin being degraded until anaphase 2 when shugoshin is deactivated
4
Q
Nucleosome depleted regions
A
Hotspots in cerevisae in promoters- unwound to allow transcription, also allows spo11 to access
