Maternal medicine - Medical disorders in pregnancy Flashcards

1
Q

Approach to maternal medical disorders on pregnancy

A

Structured framework in approach to medical disorder in pregnancy
 effect of disease on pregnancy → maternal, fetal, post-natal
 effect of pregnancy on disease → disease itself, medication

Each can be divided into pre-pregnancy, antepartum, intrapartum, postpartum periods

FDA classification of safety of medications in pregnancy

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2
Q

Contraception and sterilization in women with medical disease

Considerations

A

Considerations:
- Any increase risk due to pre-existing medical condition e.g. COCP increase risk of venous thromboembolism
- Future fertility wish? Completed family?
- Effectiveness of contraception: type, compliance, effect of medication on contraception…?
- Absolute contraindication to pregnancy e.g. Eisenmenger syndrome

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3
Q

GDM

Pathophysiology

A
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4
Q

GDM

High risk factors indicating early OGTT

A
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5
Q

GDM

Recommended screening time

A
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6
Q

Diagnosis of GDM

A
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7
Q

GDM

Maternal and fetal complications

A
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8
Q

GDM

Management plan at diagnosis

A
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9
Q

GDM

Antenatal care plan

A
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10
Q

GDM

Intrapartum and postnatal care plan

A
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11
Q

Effect of pregnancy on DM

A
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12
Q

Effect of DM on pregnancy

A
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13
Q

Pre-existing DM

Pre-pregnancy management

A
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14
Q

Pre-existing DM

Management at diagnosis

A
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15
Q

Pre-existing DM

Antenatal management

A
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16
Q

Pre-existing DM

Intrapartum management

A
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17
Q

Pre-existing DM

Postpartum management

A
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18
Q

Thyroid disorder

Physiological changes during pregnancy

A
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19
Q

Hypothyroidism

Effect of pregnancy on disease
Effect of disease on pregnancy
Management

A
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20
Q

Hyperthyroidism

Effect of pregnancy on disease
Effect of disease on pregnancy
Management

A
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21
Q

Autoimmune diseases during pregnancy

Usual disorders

A
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22
Q

Effect of pregnancy on autoimmune disorders

A
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23
Q

Effect of autoimmune disorders on pregnancy

A
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24
Q

Treatment of autoimmune disorders during pregnancy

A
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25
Q

SLE

Effect of pregnancy on SLE
Effect of SLE on pregnancy
Management

A
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26
Q

Differentiate SLE from pre-eclampsia

A
27
Q

Cardiac disease in pregnancy

Effect of pregnancy on cardiac disease

A
28
Q

Cardiac disease in pregnancy

Cardiac condition effect on pregnancy

A
29
Q

Management of cardiac condition in pregnancy

  • Contraindicated treatments
  • Treatment considerations
A
30
Q

Pre-pregnancy assessment of maternal cardiac conditions

A
31
Q

Antenatal management of maternal cardiac condition

A
32
Q

Intrapartum management of maternal cardiac conditions

A
33
Q

Epilepsy

Effect of pregnancy on epilepsy
Effect of epilepsy on pregnancy

A
34
Q

Epilepsy during pregnancy

Treatment considerations

A
35
Q

Epilepsy during pregnancy

Pre-pregnancy management

A
36
Q

Epilepsy during pregnancy

Antenatal, intrapartum and postpartum management

A
37
Q

Thrombophilia and pregnancy

Effect of pregnancy on thrombophilia

A
38
Q

Thrombophilia and pregnancy

Effect of thrombophilia on pregnancy

A
39
Q

Thrombophilia and pregnancy

Treatment

A
40
Q

Thrombophilia in pregnancy

Pre-pregnancy assessment

A
41
Q

Thrombophilia in pregnancy

Management for low-risk patients

A
42
Q

Thrombophilia in pregnancy

Management for high-risk patients

A
43
Q

Renal disease in pregnancy

Effect of pregnancy on CKD
Effect of CKD on pregnancy

A
44
Q

Renal disease in pregnancy

Pre-pregnancy management

A
45
Q

Renal disease in pregnancy

Antenatal management

A
46
Q

Renal disease in pregnancy

Considerations for renal transplant

A
47
Q

Renal disease in pregnancy

Renal transplant timing and drug choice

A
48
Q

Skin disease in pregnancy

Effect of pregnancy on eczema, acne, psoriasis

A
49
Q

Pemphigoid gestationis

Prevalence
S/S
Dx
Mx
Impact on pregnancy

A
50
Q

Polymorphic eruption of pregnancy (PEP)

Prevalence
S/S
Mx
Impact on pregnancy

A
51
Q

Prurigo of pregnancy

Prevalence
S/S
Mx
Impact on pregnancy

A
52
Q

Pruritic folliculitis of pregnancy

Cause
S/S
Mx

A
53
Q

Substance abuse in pregnancy

Prevalence
Common drugs

A
54
Q

Substance abuse in pregnancy

Obstetric and maternal complications

A
55
Q

Alcohol use in pregnancy

Prevalence
Safe level
Associated disorders

A

FASD:
- Alcohol-related neurodevelopmental disorder (ARND)
- Alcohol-related birth defects (ARBD)
- Fetal alcohol syndrome (FAS)

56
Q

Alcohol-related neurodevelopmental disorder (ARND)

Clinical features

A
57
Q

Alcohol-related birth defects (ARBD)

Clinical features

A
58
Q

Fetal alcohol syndrome (FAS)

Prevalence
Diagnostic criteria

A
59
Q

Fetal alcohol syndrome (FAS)

Clinical features

A

Facial dysmorphism: short palpebral fissure, thin vermillion border, smooth philtrum

Growth retardation: prenatal or postnatal, ≤10th percentile at any time

Brain involvement: microcephaly, structural brain abnormalities, hard neurologic signs, recurrent seizure not due to postnatal insult or fever

Neurobehavioral impairment: global cognitive/intellectual deficits, developmental delay, functional deficits, impaired self-regulation

Other features:
- Cardiac defect: ASD, VSD, aberrant great vessels, ToF
- Skeletal defect: large joint flexion contracture, pectus excavatum or carinatum, scoliosis, shortened and clinodactyly of 5th finger
- Renal defect: aplastic / hypoplastic kidney, horseshoe kidney, duplex kidney, hydronephrosis
- Ocular defect
- Auditory defect

60
Q

Cigarette smoking

Antenatal and intrapartum complications

A
61
Q

Opioid abuse in pregnancy

Antenatal, neonatal complications

A
62
Q

Ketamine and metamphetamine abuse

Antenatal and neonatal complications

A
63
Q

Cocaine abuse

Antenatal complications

A
64
Q

Substance abuse in pregnancy

Management

A