Mastitis/ breast abscess Flashcards

1
Q

What is mastitis?

A

Mastitis is defined as inflammation of the breast with or without infection

Mastitis with infection can be lactational (puerperal) or non-lactational (e.g. duct ectasia)

mastitis can lead to abscess formation

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2
Q

What is a breast abscess?

A

a localised area of infection with a walled-off collection of pus → main complication of mastitis, but it may or may not be associated with mastitis

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3
Q

What are some risk factors for mastitis?

A

(Mastitis typically develops when milk is not properly removed)
RFs:
- BREAST FEEDING
- poor latch
- cracked nipples
- use of a breast pump
- weaning
- tight fitting clothes
- trauma
- post nipple piercing
- smoking; can cause damage to the breast tissue

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4
Q

What are the causative agents of breast abscesses?

A

⇒ Lactational: staphylococcus aureus
⇒ Non-lactational: staphylococcus aureus or anaerobes

most common:
- staph aureus
- coagulase-negative staphylococci.
- Methicillin-resistant S aureusis (MRSA)

Breast infections may sometimes be polymicrobial (up to 40% of abscesses), with isolation of aerobes as well as anaerobes

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5
Q

What are some risk factors for breast abscess?

A
  • lactation
  • smoking
  • diabetes (immunosupression)
  • inflammatory breast cancer
  • mammary duct ectasia
  • periductal mastitis
  • wound infections e.g. from surgery
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6
Q

Summarise the epidemiology of mastitis

A

● Mastitis common in breast feeding women – 10%
● Lactational breast abscesses common
● Non-lactational tend to occur in 30-60 yr smokers

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7
Q

What are some causes of non-infectious mastitis?

A
  • idiopathic granulomatous (lobular) inflammation- benign disease of unknown aetiology
  • underlying duct ectasia (peri-ductal mastitis or plasma cell mastitis)
  • other inflammatory conditions (e.g., foreign body reaction: nipple piercing, breast implant, or silicone)
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8
Q

What are some causes of lactational mastitis?

A
  • Bacteria entering through breaks in the nipple
  • Prolonged milk stasis, leading to engorgement of the ducts
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9
Q

What are some causes of non- lactational/ non-puerperal mastitis?

A
  • idiopathic
  • related to malignancy
  • infection (surgery, piercings)
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10
Q

What signs of breast abscess/ mastitis can be found on history?

A
  • fever 
  • decreased milk outflow 
  • breast warmth 
  • purluent discharge from nipple or lesion
  • breast tenderness 
  • breast firmness 
  • breast swelling 
  • breast erythema 
  • flu-like symptoms, malaise, and myalgia 
  • breast pain
  • RFs: smoking, diabetes, breast feeding
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11
Q

What signs of mastitis can be found on examination?

A
  • Red, swollen, tender breast
  • increased warmth of affected area
  • erythema, possible edema
  • fluctuant, palpable mass
  • distant skin infections
  • Cracked nipple
  • Non-lactational abscess: scars or tissue distortion from previous episodes; signs of duct ectasia
  • Systemic:
    1. pyrexia of >38°C (100.4°F)
    2. tachycardia
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12
Q

What investigations are used to monitor possible mastitis?

A
  • Diagnosis usually based on presentation
  • Breast examination
  • breast ultrasound (helps differentiate b/t tumor vs abscess)
  • diagnostic needle aspiration drainage 
  • cytology of nipple discharge or sample from fine-needle aspiration 
  • milk, aspirate, discharge, or biopsy tissue for culture and sensitivity 
  • histopathological examination of biopsy tissue 
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13
Q

What is the first line approach to managing a patient with breast abscess?

A
  • ABCDE assessment
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14
Q

What is the next step if a pt with a breast abscess is found to be unstable after the ABCDE assessment?

A
  • stabilize airway, make sure they are breathing
  • Address circulation by obtaining IV access (initiating IV fluids for resuscitation)

note: rare for breast abscess to be sole reason for haemodynamic instability- check for sepsis

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15
Q

What is the next step if a pt with a breast abscess is found to be stable after the ABCDE assessment?

A
  • Take a focused history and perform a breast examination
  • on history look for signs and risk factors
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16
Q

What is the first line of management for breast abscess if there are no systemic signs or severe symptoms?

A

effective milk removal and supportive care: continue breastfeeding, if not all milk removed, use hand or breast pump to remove
- avoid bras

17
Q

What is the first line of medical management for breast abscess if there are systemic signs or severe symptoms?

A

a) Empiric antibiotic therapy:
1. panicillinase- resistant penicillins:
- “Dicloxacillin”
2. Beta- lactam hypersensitivity/ MRSA:
“Clindamycin”

b) +/- pain management:
acetaminophen or ibuprofen

18
Q

What is the second line of medical management for breast abscess after ABs and pain management?

A

Ultrasound to determine the size of the abscess

19
Q

How does management differ depending on the size found on US of the breast abscess?

A

< 5 cm:
- ultrasound- guided needle aspiration
- repeat for 2-3 days until no fluid is visible on US
- send for culture and sensitivity
> 5 cm: surgical incision + drainage

20
Q

What are the next steps of management for breast abscess if the pt has an adequate response to the antibiotics and pain killers?

A

Complete the AB course for 10-14 days

21
Q

What are the next steps of management for breast abscess if the pt has an inadequate response to the antibiotics and pain killers?

A

assess skin appearance for ischaemia/ necrosis

22
Q

What are the next steps of management for breast abscess if the pt has signs of ischaemia/ necrosis on skin assessment

A
  • surgical incision + drainage
  • deberidement of necrotic tissue
  • assess for inflammatory breast cancer
23
Q

What are the next steps of management for breast abscess if the pt shows no signs of ischaemia/ necrosis on skin assessment

A
  • US guided needle aspiration
  • Surgical incision + drainage of abscess
  • assess for inflammatory breast cancer
24
Q

What are possible complications for mastitis/ breast abscesses and its management?

A

● Sepsis
● Recurrent mastitis
● Abscess is complication of mastitis

25
Q

Summarise the prognosis for patients with mastitis/breast abscesses

A

Good:
When treated promptly and appropriately, most breast infections, including abscess, will resolve without serious complications. Resolution of mastitis after 2-3 days of appropriate antibiotic therapy is expected among most patients. 

Lactational abscesses tend to be easier to treat than non-lactational abscesses because their aetiology and pathology is better understood. Non-lactational abscesses can be multifactorial and have a greater risk of becoming chronic. 

26
Q

describe the pathophysiology of mastitis

A

In lactational mastitis, milk stasis or milk overproduction, coupled with infection from bacteria entering the breast via a traumatised nipple (e.g., cracked or fissured) and/or from the infant’s mouth, can lead to mastitis. Transient breast enlargement from maternal hormones in neonates makes them vulnerable to mastitis.