Master Drug list (effects in detail) Flashcards
botulinum toxin
prevents vesicles from connecting with membrane and releasing ACh- ACh ANT
Black widow spier venom
stimulates attach and release of vesicles with Each- AGO
Nicotine
directly stimulates nicotinic ACh receptors- AGO
curare
competitive binder for nicotinic ACh receptors
muscarine
directly stimulates muscarinic ACh receptors
atropine
competitive binder for muscarinic ACh receptors
l-dopa
precursor for DA
AMPT
inactivates enzyme that turns tyrosine to l-dopa, thus is a catecholamine ANT
reserpine
stops the transport pump of monoamines into vesicles- ANT
chlorpromazine
blocks D2 receptor
cocaine, methylphenidate
blocks DA reuptake
amphetamine
blocks reuptake of DA and NE, reverses transporters so they dump NTs into cleft
deprenyl
inhibits MAO-B (which inactivates DA)- DA AGO
MDMA
stops reuptake of NE and 5HT, reverses transporters to dump them into cleft
Fluoxetine
inhibits 5HT reuptake