mass transport in animals Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

what is haemoglobin

A

a globular protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what’s haemoglobin’s structure

A

curled up so hydrophilic side chains face outwards and the hydrophobic side chains face inwards

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

how does it’s structure make it effective

A

(side chains) makes haemoglobin soluble and good for transport in the blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

3 functions of HG

A
  • associates w oxygen in the lungs
  • transporting oxygen to the tissue
  • dissociating w oxygen in the tissues
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is association

A

process in which HG binds to oxygen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is dissociation

A

the process in which HG releases its oxygen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is partial pressure

A

concentration of oxygen (kPa)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is affinity

A

how easily the oxygen binds to the HG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

how many molecules of oxygen can bind to one molecule of HG

A

4

Hb + 4O2 —> HbO8

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

haemoglobin + oxygen = ?

A

oxyhaemoglobin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what do HG and oxygen do in the lungs and why

A

associate - in lungs, partial pressure of oxygen is high so haemoglobin has high affinity for oxygen so oxygen associates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is the partial pressure like in the lungs

A

high

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what do HG and oxygen do in the respiring tissues

A

dissociate - partial pressure in tissues is low so HG has a low affinity for oxygen, the high concentration of CO2 causes the HG to change shape and dissociate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

describe a dissociation curve and how the 4 oxygens associate with the HG

A

1 O2 - IN RESPIRING TISSUES, hard for the first O2 to associate with the iron ion (in haemoglobin) in the blood bc not quite the right shape
2+3 O2 - the association of 1st O2 causes a positive allosteric effect (change in shape) to allow 2+3 to associate easily
4 O2 - IN LUNGS, hard for 4th O2 to associate, this is bc there’s a low probability that the single O2 molecule will find an empty binding site to bind to (as 3/4 binding sites are occupied)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

how does CO2 effect how HG functions

A

HG gives up its oxygen more readily at high partial pressure of CO2, this enables more oxygen to get to cells that are respiring at a high rate

when cells respire they produce CO2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

why does HG have a high affinity for oxygen in the lungs?

A

at the gas exchange surface CO2 is constantly being removed. the pH is slightly raised due to the low conc of CO2, the higher pH changes the shape of the HG into one that enables it to load oxygen readily

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

how does decreased CO2 effect the dissociation curve

A

shifts it to the RIGHT - bohr effect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

why does HG have a low affinity for oxygen in respiring tissues?

A

in tissues, CO2 is produced by respiring cells, CO2 is acidic so pH of blood is lowered. the lower pH changes the shape of HG to one with a lower affinity for oxygen. HG releases its oxygen into the respiring tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

how does blood temperature affect dissociation?

A

increased blood temp reduces HG affinity for oxygen so more oxygen is delivered to the warmed up tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

how does CO2 conc affect dissociation

A

the higher O2 conc in tissues, the less affinity HG has for oxygen, so the harder the tissue is working the more oxygen is released

21
Q

what is the double circulatory system

A

two circuits to the circulatory system - pulmonary (lungs) and systemic (rest of the body)

when blood goes round the body it passes the heart twice

22
Q

advantages of the double circulatory system

A
  • blood pressure can be maintained at a high level

- oxygenated and deoxygenated blood doesn’t mix

23
Q

what’s the closed circulatory system

A

blood stays in the blood vessels all of the time

24
Q

advantages of the closed circulatory system

A
  • high pressure can be maintained
  • less transport fluid is needed
  • complete separation of function between organs
25
Q

what are coronary arteries

A

the heart’s own blood supply, they branch in order to supply all cardiac cells with glucose and oxygen required for respiration

26
Q

how does the blood get from the heart and back via blood vessels

A

heart —> artery —> arteriole —> capillary —> venule —> vein —> heart

27
Q

what are the different layers of a blood vessel

A

OUTWARDS

lumen (just the hole) —> endothelium layer —> elastic layer —> muscle layer —> tough outer layer

28
Q

function of the arteries

A

carry blood away from the heart and to the arterioles

29
Q

structure of arteries

A
  • thick muscle layer
  • thick elastic layer
  • great overall thickness
  • no valves
30
Q

why do arteries have thick muscle layers?

A

so they can be constructed and dilated in order to control the volume of blood passing through them

31
Q

why do arteries have thick elastic layers?

A

to keep blood pressure in the arteries high so that the blood can get to all around the body

32
Q

why are arteries overall very thick?

A

stops the artery bursting under pressure

33
Q

why don’t arteries have valves

A

blood pressure is high so blood tends not to flow backwards

34
Q

function of aterioles

A

smaller arteries that control blood flow from the arteries to capillaries

35
Q

structure of arterioles

A
  • muscle layer thicker than arteries

- elastic layer thinner than arteries

36
Q

why do arterioles have thicker muscle layers

A

the contraction of the muscle layer allows the lumen to construct, thus restricts the blood flow and controls its movement into the capillaries

37
Q

why do arterioles have thin elastic layers

A

because blood pressure is lower and doesn’t need to be kept high

38
Q

function of veins

A

transport blood slowly under low pressure from the capillaries to the heart

39
Q

structure of veins

A
  • thin muscle layer
  • thin elastic layer
  • small overall thickness
  • valves at intervals throughout
40
Q

why do veins have thin muscle layers

A

carry blood away from tissues so their constriction and dilation cant control the flow of blood to the tissues

41
Q

why do veins have a thin elastic layer

A

the low pressure of blood won’t cause it to burst and pressure is to low to create a recoil action

42
Q

why are veins overall quite thin

A

no need for a thick wall bc the pressure within the veins is too low to create any risk of bursting, also allows them to be flattened easily aiding the blood flow within them

43
Q

why do veins have valves at intervals throughout?

A

to ensure blood doesn’t flow backwards because blood pressure is low

44
Q

function of capillaries

A

exchange metabolic materials such as oxygen and CO2 between the blood and the body cells, the blood flow is much slower and allows time for the exchange of materials

45
Q

structure of capillaries

A
  • walls consist mostly of lining layer
  • numerous and highly branched
  • v narrow lumen
  • spaces between the endothelium lining cells
46
Q

why are capillaries numerous and highly branched

A

to provide a larger surface area for exchange

47
Q

in capillaries why are there spaces between the lining cells

A

allow white blood cells to escape in order to deal with infections within tissues

48
Q

why do capillary walls consist of mainly the lining layer

A

makes them extremely thin so the distance over which diffusion takes place is short - allows for rapid diffusion between blood and cells

49
Q

why do capillaries have a narrow lumen

A

so their red blood cells are squeezed flat against a side of the capillary, brings them even closer to the cells they supply oxygen to - decreased diffusion pathway