Mass Transport in Animals Flashcards
What is digestion?
Where large biological molecules are hydrolysed by enzymes into smaller molecules that can be absorbed across cell membranes
Digestion of carbohydrates
- Amylase produced by salivary glands hydrolyses starch into maltose
- Maltose hydrolysed by maltase into glucose
- Membrane bound disaccharides attached to the ileum also help hydrolyse maltose into glucose
Digestion of lipids
- Bile salts produced by liver emulsify lipids, increasing SA:V of lipid droplets
- Lipase hydrolyses lipid droplets into micelles
- Micelles contain bile salts and fatty acids
- Micelles make fatty acids soluble and bring to cell lining the ileum
- Fatty acids absorbed by diffusion
- Triglycerides reformed in cells
- Vesicles move to membrane
Digestion of proteins
- Endopeptidase hydrolyse peptide bonds within polypeptide
- Exopeptidase hydrolyses peptide binds at ends of polypeptide
- Membrane bound dipeptidase hydrolyse peptide bonds between dipeptides
Amino acid absorption
- Co-transport with Na+
- Na+ pumped out, creating low concentration of Na+
- Na+ diffuses in via co-transport
- Amino acids co-transported in too against concentration gradient
What is haemoglobin?
A protein with a quaternary structure found in red blood cells. Oxygen binds forming oxyhaemoglobin
Oxyhaemoglobin dissociation curve
- Oxygen loads onto haemoglobin at high partial pressure of oxygen
- Haemoglobin becomes saturated with oxygen
- Oxygen unloads at the cells where partial pressure of oxygen is low
The Bohr shift
- Oxyhaemoglobin curve shifts to the right
- Organisms respire, increasing concentration of carbon dioxide in blood
- Increased blood acidity decreases haemoglobin affinity for oxygen
- Oxygen unloads more easily at respiring cells, becoming less saturated with oxygen
Organisms in low oxygen environments oxyhaemoglobin curve
- Lower partial pressure of oxygen in lungs
- Haemoglobin has a higher affinity for oxygen
- Able to load oxygen at lower partial pressure of oxygen
Organisms in high oxygen environments oxyhaemoglobin curve
- Higher partial pressure of oxygen in lungs
- Haemoglobin has a lower affinity for oxygen
- Unload more oxygen at cells
- Useful for animals with high rate of respiration (eg. Small SA:V animals loose more heat per gram)
Arteries structure (+ function)
- Narrower lumen (blood at high pressure)
- Elastic tissue and folded endothelium (stretch and recoil, maintaining smooth pressure)
- Thick muscle (contract and change flow of blood)
Vein structure (+ function)
- Wide lumen (blood at low pressure)
- Smooth endothelium (reduce friction)
- Thin muscle (can’t contract)
- Valves (prevent backflow of blood)
Capillaries structure (+ function)
- One cell thin endothelium (short diffusion distance)
- High surface area (fast rate of diffusion)
- High hydrostatic pressure at start of capillaries (outward pressure forces fluid out capillaries)
Heart structure (+ function)
- Aorta (oxygenated blood to body)
- Pulmonary vein (oxygenated blood from lungs)
- Left atrium (pimps blood to ventricle)
- AV valves (open when pressure is greater in atria)
- Left ventricle (thicker muscle, pumps blood around body)
- Pulmonary artery (deoxygenated blood to lungs)
- Vena Cava (returns blood from body)
- Right atrium (pumps blood to ventricle)
- SL valves (open when pressure is higher in ventricles)
- Right ventricle (pumps blood to lungs)
Cardiac cycle
- Atria contracts
- Pressure higher in atria than ventricles
- AV valves open and SL valves close
- Ventricles contract
- Pressure higher in ventricles
- AV valves close and SL valves open
- Atria and ventricles relax
- Pressure higher in atria than ventricles
- AV valves open and SL valves close
Cardiac output formula
Cardiac output = stroke volume x heart rate
Atheroma formation
- Build up of fatty plaque on inside of artery
- Can lead to thrombosis (blood clot) or aneurysm (swelling)
- Blocked coronary arteries can lead to myocardial infarction (heart attack)
- Reduces flow of oxygen and glucose to heat and can’t respire
Risk factors for cardiovascular disease
- High blood pressure
- High blood cholesterol / poor diet
- Cigarette smoking
What is pressure filtration?
The way a substances move out of the capillaries into the tissue fluid
Tissue fluid formation
- Hydrostatic pressure higher in blood than tissue fluid
- Water and small molecules forced out
- Large molecules stay inside capillary
- Pressure drops along capillary bed as water moves out
Tissue fluid return
- Water potential in blood becomes lower than tissue fluid as proteins remain in blood
- Water moves into capillary by osmosis
- Water moves down pressure gradient so hydrostatic pressure drops in capillary
- Tissue fluid drains into the lymph