Mass spec Flashcards
1
Q
What are soft source types?
A
Bonds remain intact
2
Q
What are hard source types?
A
Cause fragmentation
3
Q
What kind of source type is electrospray (ESI)?
A
Soft
4
Q
How does ESI work?
A
Solution based - placed in fine capillary with a charge at the end where either protonation occurs or Na+ picked up, larger droplets get smaller through heating
5
Q
What is a downside to ESI?
A
Causes multiple charges to molecules with multiple functional groups that have different m/z
6
Q
What kind of method is MALDI?
A
Soft
