Marty's Study Guide Flashcards
Recommendations on breast self-exam
USPSTF - does not recommend
ACS - BSE is an option beginning at 20y
Either way, women should be trained on how to do it if they decide that they are going to
Clinical breast exam recommendations
USPSTF - insufficient evidence outside of mammography
ACS - clinical breast exam Q3y for 20y-40y and yearly for >40y
Waist circumference cutoffs for increased risk
Men >40in
Women >35in
Who needs to have more frequent PAPs?
Immunocompromised
HIV+
History of CIN2, CIN3, Cancer
in-utero exposure to DES
Skin exam recommendations
USPSTF - insufficient evidence
ACS - part of yearly health maintenance
Endometrial cancer screening recommendations
No routine screening
Women with HNPCC - annual screening with endometrial biopsy beginning at 35y
Lung cancer screening recommendations
Screen in patients 55-65y with a 30+ pack year history, if quit within past 15y
Done with low-dose CT
Breast cancer screening recs
USPSTF - biennial starting at 50y
ACS - annual starting at 40y
DDx of nipple discharge
Physiologic: -Pregnancy -Breast stimulation Pathologic: -Prolactinoma -Cancer -Hormone imbalance -Trauma -Breast abscess -Medications
Definition of osteopenia
T-Score from -1 to -2.5
Dosing of calcium in females
Premenopausal = 1000mg daily
Postmenopausal = 1500mg daily
Recs for Calcium & Vit D supplementation
USPSTF recommends against supplementation in healthy pre or postmenopausal females. Instead, get it through diet & incorporate weigh-bearing exercise
Osteoporosis screening
DEXA if >65y or FRAX risk is >9.3% over 10y
Diabetes screening recs (adults)
ADA:
Screen if BMI >25 and a risk factor
USPSTF - Screen all adults with HTN
HbA1c cutoffs for screening
5.7-6.4% = prediabetes
> 6.5% = DM
Bethesda system reports
- Specimen adequacy
- -Over 5,000 squamous cells with endocervical cells - General
- -Is there intraepithelial lesion or cancer? - Interpretation
- -ASC, LSIL, HSIL, SCC
Pt with ASC-US & negative HPV
Repeat cotesting in 3y
Ages for HPV vaccination
Gardasil = 9-26 Cervarix = 10-25
Indications for statins
1) Clinical ASCVD (ACS, CVA/TIA, PVD)
2) 40-75y with DM
3) >21y with LDL >190
4) 40-75y with 10y ASCVD risk >7.5%
How often to screen fasting lipids
Every 4-6y in adults 20-79y
Adult immunizations
One-time TDaP booster for ages 11-64 then Td booster every 10y
Zoster vaccine at 60y
Pneumococcal vaccine at 65y (or earlier if risk factors)
Influenza yearly
Reasons for pneumococcal vaccine before 65y
Chronic lung dz Chronic renal dz Chronic liver dz Asplenia Immunocompromised Smokers Long-term care facilities
Characteristics of a good screening test
1) Can be treated
2) Latent phase of dz
3) Screen acceptable to pts and reasonable cost
Screening for HepC
One-time screening for adults born between 1945-1965
Target BP
Normally 140/90
If over 60y 150/90
All ages with DM or CKD: 140/90
Antihypertensives in blacks
Must contain thiazide or CCB
Antihypertensives in CKD
Include ACEi or ARB (regardless of race)
Antihypertensives in non-blacks
Thiazide
CCB
ACEi
ARB
When to get next c-scope based on findings
1-2 small tubular adenomas = 5-10y
3+ tubular adenomas = 3y
Advanced sleep phase syndrome
Internal clock is set to sleep from early evening to very early morning
Seen in the elderly
Most effective treatment for insomnia
CBT-I
Minimum length for MDD
2 months
Assessing suicide risk
Sex (male) Age (45) Depression Previous attempts EtOH or other substance Rationality impaired (psychosis) Social support lacking Organized plan No significant other Sickness
Score of 7+ = hospitalization
SE’s of SSRI’s
Headaches
Insomnia or Sedation
Nausea/Diarrhea
Presentation of depression in hispanics
More often somatic complaints
Immigrant hispanics have 50% lower depression rates. US born hispanics are similar to other ethnic groups.
Suicidality in relation to age
Attempts do not increase, but completion rates do
Drug overdose is most common means of suicide in the elderly
Presentation of compartment syndrome
6 P’s:
- Pain
- Pallor
- Pulselessness
- Paresthesia
- Paralysis
- Perishing cold
DDx of traumatic ankle pain
Lateral ankle sprain Peroneal tendon tear Fibular fracture Talar dome fracture Subtalar dislocation
Most commonly sprained medial ankle ligament
Deltoid ligament
Sprained ligaments with inversion & plantar flexion
Anterior talofibular**
Calcaneofibular
Posterior talofibular
**most often injured ligament
Ankle anterior drawer test
Tests anterior talofibular ligament
Ankle inversion stress test
Tests calcaneofibular ligament
Sprained ligaments with eversion & dorsiflexion
Deltoid ligament
Anterior tibiofibular ligament
Grading sprains
Grade I = little/no impairment
Grade II = some impairment & some stretching on exam
Grade III = complete tear, no weight bearing, no definite stretch endpoint
Ottawa ankle rules
1) Malleolar pain
2) Pain in either distal posterior malleolus or non-weight bearing (immediately & in ED)
Ottawa foot rules
1) Midfoot pain
2) Navicular bony tenderness or base of 5th metatarsal or inability to bear weight (immediately & in ED)
Negative inversion test
Inversion of ankle shows laxity of the calcaneofibular ligament
Crossed-leg test
Cross legs, apply pressure to medial knee
Pain at the ankle indicates high ankle (syndesmotic) sprain
Effect of thyroid on periods
Hypothyroid = heavy periods
Hyperthyroid = light periods
Most common symptoms of hyperthyroidism
Tachycardia
Sweating
Heat intolerance
Fatigue
Causes of hyperthyroidism
Graves’ Disease (toxic diffuse goiter)
Toxic nodular goiter (single or multinodular)
Thyroiditis
Drug-induced (amiodarone, lithium)
Risk factors for thyroid nodule to be malignant
Male gender Extremities in age Rapid growth Local invasion (dysphagia, hoarseness) History of head/neck radiation FH of thyroid cancer
Causes of hypothyroidism
Hashimoto’s thyroiditis
Postpartum thyroiditis
Subacute thyroiditis (de QuerPAIN)
Riedel thyroiditis
What is considered normal RAIU?
15-30%
Ways to evaluate the thyroid
Nodule - US
Hyperthyroidism - RAIU or US
RAI vs. thyroidectomy
RAI - less permanent hypothyroidism
Surgery - less recurrence of dz
Restrictions after RAI treatment
No pregnancy for 6mo
No getting someone pregnant for 4mo
No close contact with young kids or pregnant women
Follow up for RAI treatment
Follow TSH every 2mo
Teach symptoms of hypothyroidism
Fundoscopic findings of non-proliferative retinopathy
Retinal hemorrhages
Cotton wool spots (previous infarction)
Microaneurysms
Fundoscopic findings of proliferative retinopathy
Neovascularization
SE’s of metformin
Renal insufficiency
B12 deficiency
T2DM Treatment algorithm
1) Lifestyle change + metformin
2) Add sulfonylurea or basal insulin
3) Intensify insulin regimen
Vaccines for DM patients
Influenza
Pneumococcal
HBV if unvaccinated
When to get first eye exam in DM patients
T1DM - 5y after diagnosis
T2DM - at diagnosis
Optimal blood glucose range
Fasting: 80-120
Postprandial:
Grades of ulcers
1: Superficial
2: Involves ligament, tendon, or fascia
3: Deep with abscess or osteomyelitis
4: Gangrene of forefoot
5: Extensive gangrene
Duration of anticoagulation after DVT
Provoked: 3mo
Unprovoked: extended if low-moderate bleeding risk
Active cancer: Extended
Highest dose of HCTZ
Doses >25mg don’t provide added efficacy
Labs to get on newly diagnosed HTN patients
Urinary albumin/Cr
Serum Calcium
When to initiate aspirin
Men 45-79 (for MI risk)
Women 55-79 (for CVA risk)
*Only once BP is under control, to minimize hemorrhagic stroke risk
SE’s of ACEi
Up to 35% Cr increase
Angioedema
Chronic cough
CCB SE’s
Leg edema
ECG abnormalities suggestive of paroxysmal afib
Abnormal P wave
PAC’s
Bradycardia
Delta wave
WPW
Findings in HOCM
LVH
Q waves in I, AVL, V4-V6
Most common causes of back pain
Lumbar strain
Age-related DJD
Herniated disc
Pain with back flexion
Hernation
Osteoarthritis
Muscle spasm
Pain with back extension
Degenerative disease
Spinal stenosis
Pt unable to heel walk
L5 disc herniation or peroneal n. injury
Pt unable to walk on toes
S1 disc herniation or tibial n. injury
Nerve route of DTR’s
Ankle - S1, S2
Patella - L3, L4
Biceps - C5, C6
Triceps - C7, C8
Passive straight leg raise (Lasegue’s sign)
Differentiates tight hamstring vs. sciatic nerve pain
FABER test
Positive if pain is in the hip joint or SI joint
How often can a joint receive a steroid injection?
Only once per month & only 3 max per year
What steroid is used in joint injections?
Triamcinolone
Indications for carpal tunnel syndrome electrodiagnosis
1) Symptoms fail to improve
2) Motor dysfunction present
3) Thenar atrophy present
AAA screening
One-time abdominal US in MEN 65-75 who have any history of smoking
Synovial fluid PCR can diagnose septic arthritis infection due to:
Yersinia Chlamydia Gonorrhea Ureaplasma Lyme dz
NSAIDs effect on other drugs
Decreases antihypertensive effectiveness
Increases anticoagulant & sulfonylurea effectiveness
Chlamydia screening guidelines
All sexually active women
Recommended folic acid supplementation
All fertile women 400-800mg daily
DM or epilepsy = 1mg
Previous NTD = 4mg
Chadwick’s sign
blue-purple hue of cervix & vaginal walls during pregnancy
When to start fetal heart tones
10-12w
aka when the uterus is above the pubic symphysis
When can fetal movement be detected?
18-20w
When is abortion legal?
Up to 22w
Ectropion definition
Central cervix is red due to endocervical epithelium protrusion. Occurs in women on OCP’s. Means nothing.
Results of progesterone testing in a pregnant patient
> 25 = likely sustainable pregnancy
At what hCG level is an IUP detectable by US?
TVUS >1500
Transabdominal >5000
Reliability of US in dating
1t = 1 week 2T = 2 weeks 3T = 3 weeks
Do not change dates due to a 3TUS
Options for incomplete abortion
1) Expectant mgmt
2) D&C (1T) or D&E (2T)
3) Vaginal misoprostol
Nonasthmatic eosinophilic bronchitis
Chronic cough (>8w) Better with inhaled steroids Normal spirometry
Dx with induced sputum or lavage showing eosinophils
Acute sinusitis vs. chronic sinusitis
Acute: >7-10d
Chronic: >12w
When to give abx for acute bacterial sinusitis
Fever > 101
Moderate-severe pain
Worsening/Failure to improve after 7d
Diagnosis of asthma
1) Obstructive spirometry
2) Improvement of FEV1 by 12% or percent predicted FEV1 by 10% after bronchodilator
When to screen for asymptomatic bacteruria in pregnant pts?
12-16w
When to administer Rhogam
- 28 weeks
- Any prenatal bleeding
- Within 72h postpartum
When to get structural US
18-20w
BP cutoffs for severe preeclampsia or sever gHTN
SBP >160 or DBP > 110 for at least 6h
Diagnosis of gDM
2 out of 3 glucose measurements abnormal
When to start OCP’s postpartum
Progestin-only can be started immediately postpartum
COC’s should wait 4 weeks (may suppress initial milk & possible DVT)
When to screen for gDM
GTT at 24-28 weeks
PE signs of acute pancreatitis
Grey-Turner’s sign - flank bruising
Cullen’s sign - periumbilical bruising
Which dermatophyte infx must be treated orally?
Tinea capitis
Tinea unguium
Tx for tinea unguium
Oral terbinafine or itraconazole pulse therapy
Tx for Tinea capitis
Oral griseofulvin
Margins for SCC excision in the clinic
If lesion is 2c, refer
What drugs should pts with enlarged prostate avoid?
Caffeine
Anticholinergics:
-Decongestants
-Antihistamines
HRT effect on breast cancer
Combined Estrogen & Progesterone use for >3y increases breast cancer risk
Uterine bleeding with HRT
Bleeding within first 12m can be normal (physiologic)
After 12m of therapy always requires evaluation
Endometrial thickness in postmenopausal women
If
Calcium & Vit D requirements for women over 50y
1200mg Ca
600 IU Vit D
Duration of different headache types
Migraine: 4-72h
Tension: 30m-7d
Cluster: 15m-3h
Number of HA’s needed to diagnose by HA type
Migraine & Cluster: 5
Tension: 10
How often should prenatal visits be?
1T & 2T: Q4wks
29w-35w: Q2w
36w-birth: Q1w
When to offer prenatal testing?
Triple screen & CVS: 9-14w
Quad screen & amniocentesis: 15-22w
Increased maternal serum AFP is associated with:
NTD
Gastroschisis, Omphalocele
Multiple gestation
Wrong dating
Decreased maternal serum AFP is associated with:
Trisomy 18 & 21
Fetal demise
Wrong dating
Quad screen results for Trisomy 18 & 21
All down Edward
T21: MSAFP & Estriol down
Migraine prophylaxis drugs
Propranolol
Divalproex, Topiramate, Gabapentin
Amitryptiline
Verapamil
What is considered controlled HA?
Less than 2 HA’s per week or 8 per month. And they are relieved with acute treatment.
What % of PUD is malignant?
2% so refer any known PUD to a specialist
Workup for dyspepsia
1) Rule out warning signs
2) Empiric PPI trial
3) H. pylori testing
Fecal immunochemical testing vs. FOBT
FIT only for occult lower GI bleeding
First line treatment for H. pylori
Triple therapy:
- PPI
- Amoxicillin
- Clarithromycin
Quadruple therapy
- PPI
- Flagyl
- Tetracycline
- Bismuth
Salvage therapy for H. pylori
PPI
Amoxicillin
Levofloxacin
HIV screening recs
Patients 15-65 and those at increased risk. All pregnant women
Syphilis screening recs
Those at increased risk
Criteria for strep throat
One point for each:
- Fever >38
- Absence of cough
- Tonsillar exudates
- Anterior cervical LAD
- Age
Indications for abx in AOM
1) Children under 2y
2) Children >2y with fever >39, otalgia for >48h, bilateral AOM, otorrhea, toxic appearance
So normal children >2 with unilateral mild AOM can be observed
Empiric pneumonia abx therapy in children
0-3w: Amp & Gent
3w-5y: Amp or Ceftriaxone IP; Amox if >3mo as OP
5y-adolescence: Azithromycin
DM screening in children
All children with BMI>85th percentile at age 10y and then Q2y
Lipid screening in children
All children with BMI >85th percentile
Lipid goals for children
Total
Indications for lipid medications in children
LDL > 190
LDL > 160 with risk factors
Only in children over 10y & have achieved Tanner stage 2 or menarche
Indications to screen for hepatic steatosis in children
At 10y if BMI >95th percentile or >85th with risk factors.
Refer to GI if AST or ALT are >2x normal
Weight mgmt for obese children
If under 7y:
- Maintain weight
- If complications present, lose 1lb/mo until 85th percentile
If over 7y:
-Weight loss until 85th percentile
Best test for UE weakness
Pronator drift
Tests to get for suspected CVA
Accucheck CT/MRI Renal function/Lytes ECG Trops CBC Coags SpO2
Criteria for immediate afib cardioversion
Mgmt of Afib patients
High risk - anticoagulation
Low-Mod risk - ASA, ASA+Plavix, or anticoagulation
Cause of viral croup
Parainfluenza
Complications of strep throat
Post-strep GN Rheumatic fever Peri-tonsillar abscess Mastoiditis Meningitis
Vaccines required prior to starting school
2 Varicella & MMR
3 HBV
5 DTaP & Polio
When can rotavirus vaccines be given?
15 weeks-8 months
Indications for annual PPD testing in children
HIV+ children
Incarcerated adolescents
Criteria for ADHD
Child >6y
Symptoms more frequent or severe than other children of same age
Behaviors present in 2+ settings
Behaviors present for >6mo
Definition of colic
Crying for:
>3h per day
>3d per week
>3 weeks
Child must be otherwise healthy child age 2w-4mo
Fever workup in newborn
If under 2mo:
- CSF
- Urine
- Blood
Arm adducted & internally rotated
Posterior dislocation
Actions of the rotator cuff muscles
Subscapularis = IR
Infrapinatus = ER
Teres minor = ER
Supraspinatus = initiates ABduction
Tests for biceps tendonopathy
Speeds or Yergason’s tests
Tests for rotator cuff pathology
Forced IR & ER
Empty beer can test
Apley’s Scratch test (impingement)
Criteria for chronic fatigue syndrome
> 6mo of disabling fatigue plus 4 of:
- Impaired memory/concentration
- Post-exertional malaise
- Tender LAD
- Sore throat
- HA
- Myalgias
- Arthralgias
Lab workup of fatigue
CBC
ESR
Iron studies
TSH
What to get after diagnosis of CRC
CT abd/pelvis
CXR
CEA
Surgical/Onc consult
HEEADSS
Home Education/Employment Eating Activities Drugs Sexuality Safety/Violence Suicide/Depression
Signs indicative of testicular torsion
Blue dot sign
Absent cremasteric reflex
Sign indicative of epididymitis
Prehn sign
Physical lifting of the testes relieves pain.
Symptoms of HSP
Nonthrombocytopenic purpura Arthralgia Abdominal pain GI bleeding Nephritic syndrome \+- scrotal pain
What intraabdominal pathology can cause referred scrotal pain?
Retrocecal appendicitis
Viability of torsed testi based on time
6h = 90% 12h+ = 50% 24h+ = 10%
When is the meningococcal vaccine given?
1st dose at 11-12y
2nd at 16y
Types of testicular tumors
Germ cell tumors: -Seminoma -Yolk sac (kids) -Embronal cell tumor -Teratomas -Mixed GCT's Choriocarcinoma
Non germ-cell tumors
- Leydig
- Sertoli
Acute vs chronic bronchitis
Acute = under 3w Chronic = at least 3mo for the past 2y
Spirometric Dx of COPD
FEV1/FVC ratio
COPD severity (FEV1)
>80% = mild 50-79% = mod 20-49% = severe
Therapy for moderate COPD
- Inhaled anticholinergics (ipratropium/tiotropium)
- SABA
Therapy for sever COPD
- Inhaled steroids
- LABA
- Anticholinergic
- SABA
Indications for abx in a COPD exacerbation
1) dyspnea, ^sputum, purulence
2) purulence & one of the above
3) requiring intubation
Dementia DSM-IV criteria
Acquired impairment in memory & one of more cognitive domains:
- Executive function
- Language
- Praxis (motor)
- Gnosis (recognition)
Labs to get in pt suspected of dementia
CBC BMP Calcium TSH B12 (no folate) \+/- RPR \+/- Neuroimaging
Most common causes of dementia
Alzheimer’s
Vascular dementia
Lew body dementia
Symptoms of Lewy body dementia
Dementia
Delirium
Parkinsonian Sx
Hallucinations
DDx corneal arcus
Arcus senilis = benign
Arcus juvenilis = HLD & possible CAD
Causes of delirium in a demented patient
Elelctrolyte disturbance UTI Respiratory infx Urinary retention Pain
Normal post-void residual
200cc = abnormal
SE’s of Haldol
Sedation
Constipation
EPS & TD
QT prolongation
What medications can precipitate or worsen delirium?
Sedating meds
Anticholinergics
Medications to treat dementia
AchE inhibitors (Donepezil) Memantine (NMDA receptor antagonist) Olanzapine & Resperidone
`When to give peripartum GBS prophylaxis
1) Women who screened positive for GBS
2) Unknown GBS status and preterm or PROM
Normal fetal HR
110-160
Normal FHT variability
6-25 bpm
What is considered a reactive FHT?
2+ accels over 20 mins
Accels must be 15bpm and last 15 seconds
Definition of active labor
Strong regular contractions Q3-5m and cervical dilation of 4-5cm
Thickness of a non-laboring cervix
3cm
Can base % effacement off of this value
Contraindications to digital cervical exam
Patient-reported vaginal bleeding
Undocumented placental location
PPROM
Stages of labor
First Stage:
- Latent = contractions
- Active = 4cm dilated
Second stage:
Full dilation to birth
Third stage:
Baby to placenta
FHT tracing categories
Cat I:
Moderate variability, no late or variable decels
Cat III:
No variability, recurrent late or variable decels
Mgmt for late decels
Place pt on her l side
Monitor maternal BP
Supplemental O2
Definition of failure to progress in labor
No cervical change for 2h during the active phase of labor
What are the cardinal movements of labor?
Engagement Descent Flexion Internal rotation Extension External rotation Expulsion
Postpartum hemorrhage causes
4T’s
- Tone
- Trauma (perineal or cervical)
- Tissue (retained placenta)
- Thrombin (coagulopathy)
When it betamethasone appropriate for fetal lung maturity?
24-34w
Age of MI in relative that gives increased risk for CAD
Male relative
What drugs lower mortality in systolic CHF?
ACEi
Carvedilol
Eplerenone
Criteria for menorrhagia
> 80cc of blood loss
Treatment options for PMS
Danazol (androgenic/progesterone)
OCP’s
SSRI during menses
Types of “dizziness”
1) Presyncope
2) Disequilibrium
3) Vertigo
Meniere’s dz triad
1) Unilateral hearing loss
2) Tinnitus
3) vertigo
Head thrust test
Positive - peripheral lesion
Normal - central lesion
Treatment for BPPV
Epley maneuver
Treatment for Meniere’s disease
Diuretics
Low salt diet
Classic signs of a TORCH infx
Microcephaly
Hepatosplenomegaly
Purpuric rash
Dx of congenital rubella
Anti-rubella IgM
Dx of congenital toxoplasmosis
Anti-toxo IgM
Dx of congenital CMV
Urine culture
Symptoms of congenital CMV
Microcephaly Sensorineural hearing loss IC calcifications Purpuric rash HSM
What are mandatory on the newborn metabolic screen?
PKU
Hypothyroidism
PKU symptoms
Vomiting
Hypotonia
Musty odor
Decreased hair/eye pigmentation
Symptoms of homocystinuria
Marfanoid body habitus
Hypercoagulable state
Niemann-Pickk symptoms
Heptatomegaly Ataxia Seizures Developmental delay Cherry-red macula
Hurler syndrome symptoms
HSM
Corneal clouding
Developmental delay
Von Gierke’s disease symptoms
Hypoglycemia
HSM
Metabolic acidosis
When to screen for autism
18m & 2y
Calorie requirements of neonates
Normal: 100-120 cal/kg/day
Preterm: 115-130 cal/kg/day
Most common neoplasm in infants
Neuroblastoma
Which infant tumor crosses the midline?
Neuroblastoma can
Wilms’ (nephroblastoma) cannot
Workup of suspected neuroblastoma
Urine or serum catecholamines (VMA & HVA)
CXR - for mets
Skeletal survey
Abdominal US
When for children to first go to the dentist?
Within 6mo of first tooth eruption
When can a child ditch their booster seat?
At 4’9”
When can a child face forward in the car?
2y or when they outgrow their small carseat
When should a bottle be stopped for children?
By 12-15mo
When to screen for anemia?
12mo & prior to kindergarten
SE’s of stimulant use to treat ADHD
Appetite suppression
Tic disorders
Insomnia
Decreased growth velocity
HTN classes in children
99th+5 = Stage 2 HTN
Secondary causes of HTN
Umbilical artery/venous access UTI w/ parenchymal scarring Catecholamine excess FH of renal dz Coarctation of the aorta
Criteria for positive PPD test
> 5mm in high risk
10mm in mod risk
15mm in low risk
Normal I:E ratio
Inspiration:Expiration
Normal is 1:2 or 1:3
What does stridor signify?
Inspiratory: Laryngeal obstruction
Expiratory: Tracheobronchial obstruction
Both: Glottic or subglottic obstruction
Weekly albuterol need in well-controlled asthma
Less than 2x per week
Definition of unstable angina
1) Chest pain at rest
2) New onset angina (past 4-6w)
3) Angina that is worsening