Markers of Inflammation

Question 1

Antigen

Answer 1

Foreign substance that elicits immune response (toxins, foreign cells, pathogens)

Question 2

Antibody

Answer 2

Proteins produces by B-cells in response to an Antigen

-bind to antigens and disable them by signaling other immune defenses

Question 3

IgG
when is it produces?
what does it indicate?

Answer 3

• In primary response
• formation AFTER IgM
• marker of resolving or prior infection

Question 4

Only class that crosses the placenta

Answer 4

IgG

Question 5

IgM
when is it produces?
what does it indicate?

Answer 5

• 1st class produced in response to infection

- marker of recurrent or recent infection, then subsides

Question 6

If IgG is present and IgM is absent?

Answer 6

Infection occurred in past

Question 7

If IgG is present and IgM also present?

Answer 7

infection is current or occurred in recent past

Question 8

IgA
where is it found?
what is its main function?

Answer 8

Found in bodily secretions- tears, saliva, intestinal mucus, breast milk.

Mucosal immunity- protects against entrance of pathogens

Question 9

IgE

What kind if problems/infections is it related to?

Answer 9

allergic reactions

parasitic infections

Question 10

If an antigen is positive, the ____ is present.

Answer 10

infecting organism is present

Question 11

Antigen tests help with what?

Answer 11

Help shorted the “window period”

-positive before antibody tests are positive

Question 12

ESR

Answer 12

Nonspecific test used to detect illness associated with acute and CHRONIC INFLAMMATION
(inflammation, advanced neoplasm, tissue necrosis or infarction)

Question 13

C-reactive protein

Answer 13

Nonspecific test primarily used to detect bacterial infection and inflammatory disorders- ACUTE INFLAMMATION

Question 14

Patient with hx of diverticulitis and symptomatic diverticulosis but you do not want to order another CT scan. Would you order ESR or CRP?

Answer 14

CRP