MARK KLIMEK Flashcards
First generation antipsychotics: Common ending and three examples
Phenothaizines (-zine’s); chlorpromazine, promethazine, hydroxyzine
Small doses are antiemetics, high doses they are the MAJOR TRANQUILIZER
Side effects of phenothaizines
ABCDEFG
Anticholinergic (dry mouth), blurred vision, constipation, drowsiness, extrapyramidal symptoms, “f”otosensitivity, aGranulocytosis
Teaching points with Phenothaizines
Report sore throat and s/s of infection to doctor, never stop the -zine
1 nursing diagnosis for Phenothaizines
Safety; Risk for injury
What are the two classes of psych drugs that have a deaconate form? (two classes, one specific drug)
Phenothaizines, Haloperidol, ziprasidone (GeoDon)
Three examples of tricyclic antidepressants
amitriptyline, imipramine, trazodone
Side effects of tricyclic antidepressants
ABCDE
Anticholinergic (dry mouth), blurred vision, constipation, drowsiness, euphoria
How long do you have to take tricyclic antidepressants for there to be an effect?
2-4 weeks
What are benzodiazepines used to treat? Two examples
Antianxiety meds, MINOR TRANQUILIZER (-ZEP’s); also used for induction of anesthetic, muscle relaxant, alcohol withdraw, seizures, facilitates mechanical ventilation
lorazepam, diazepam
How long can you take benzodiazepines?
Tranquilizers work quickly, must not take for more than 2-4 weeks
1 nursing diagnosis for benzodiazepines
SAFETY; risk for injury
Side effects of benzodiazepines
ABCD
Anticholinergic (dry mouth), blurred vision, constipation, drowsiness
Three examples of monoamine oxidase inhibitors
isocarboxazid, phenelzine, tranylcypromine
Side effects of MAOI’s
ABCD
Anticholinergic (dry mouth), blurred vision, constipation, drowsiness
Teaching points for MAOI’s
To prevent severe, acute and sometimes fatal hypertensive crisis; the patient must avoid all foods containing tyramine:
BAR (bananas, avocados, raisins and all other dried fruits), no organ or preserved meats, no cheese except mozzarella and cottage, no alcohol, yogurt, elixirs, tinctures, caffeine, chocolate, licorice, soy sauce, and no OTC drugs
What are the three side effects of Lithium?
3 P’s: Polyuria, pooping (diarrhea), paresthesia (tingling/numbness)
What is the normal range for Lithium? What is the toxic level and toxic effects?
Normal is 0.6- 1.2; toxic is above 2 in which patient would experience severe diarrhea, tremors, and metallic taste
What other electrolyte does Lithium effect and how so?
1 nursing intervention is to increase fluids; watch for dehydration and sodium levels. Low sodium makes lithium more toxic; if someone is on Lithium and becomes dehydrated, give sodium as well as fluids (don’t give water!!)
What are the side effects of fluoxetine?
ABCDE
Anticholinergic (dry mouth), blurred vision, constipation, drowsiness, euphoria
What are some teaching points for fluoxetine?
Causes insomnia, must give before noon- if BID give at 6a and noon,
When changing the dose for an adolescent or young adult, there is an increased risk for suicide.
What is haloperidol used to treat?
Tranquilizer
Side effects for haloperidol
ABCDEFG
Anticholinergic (dry mouth), blurred vision, constipation, drowsiness, EPS, “f”otosensitivity, aGranulocytosis
What is Neuroleptic Malignant Syndrome?
Elderly patients may develop NMS from overdosage of haloperidol. NMS is potentially fatal hyperpyrexia, anxiety and, tremors with temperatures up to 104. Dosage for elderly patient should be half of usual adult dose.
What are some teaching points with haloperidol?
SAFETY; risk for injury
Only antipsychotic med you can use with pregnant women!
What is clozapine used to treat?
Second generation antipsychotic used to treat severe schizophrenia; NEW MAJOR TRANQUILIZER, -ZAPINE’s
Side effects of clozapine
SEVERE agranulocytosis
What is the generic name for GeoDon?
ziprasidone (prolongs QT interval)
What does sertraline treat?
antidepressant; SSRI
Teaching points with sertraline
Also causes insomnia but you can give it in the evening
Watch for interactions with St Johns Wort (serotonin syndrome) and warfarin (bleeding); sertraline increases chance of toxicity of other drugs
Side effects of sertraline
SAD Head
Sweating Apprehensive (impending sense of doom) Dizzy Headache
Creatinine
0.6-1.2
INR
Warfarin therapy: 2-3; above 4 is bad
Hemoglobin
12-18
Hematocrit
36-54
PO2
78-100
BNP
<100 (best indicator of CHF)
WBC
Total (5,000-11,000)
ANC (>500)
CD4 (>200)
Albumin
3.4-5.4
Calcium
9-11
Magnesium
1.3-2.1
Phosphate
3.0-4.5
Chloride
98-106
What is the earliest sign of any electrolyte disorder?
Numbness and tingling (paresthesia)
What is the universal sign of electrolyte imbalance?
Muscle weakness (paresis)
What do -kalemia’s do?
The same as the prefix except for urine output and heart rate.
Key teaching with potassium IV
NEVER PUSH IV K AND NEVER >40/L
What is the treatment for hyperkalemia?
D5W with regular insulin (temporary fix)
Polystyrene sulfonate (PO/Rectal) and then treat hypernatremia with IV fluids
What do the -calcemia’s do?
The opposite of the prefix; no exceptions
What are the two signs that indicate hypocalcemia?
Chvostek’s: cheek tap
Trousseau’s: hand spasm with BP cuff
What do the -magnesmia’s do?
The opposite of the prefix; no exceptions
What should you think of with hypErnatremia? S/s?
dEhydration; hot, flushed, dry, thready pulse, rapid HR
What should you think of with hypOnatremia? S/s?
Overload; crackles, distended neck
When would you first auscultate a fetal heart?
8 weeks
When would you most likely auscultate a fetal heart?
10 weeks
When should you auscultate a fetal heart by?
12 weeks
Nagele’s rule
First day of LMP, add 7 days, subtract three months
Weight gain in pregnancy (total and by trimester)
Total: 28 (+/- 3)
1st trimester: 1lb/month (3lbs)
2nd/3rd trimester: 1lb/week
**after 12 weeks, take the week and subtract 9
Fundal heights
Not palpable until week 12, will reach umbilicus by weeks 20-22
Time period for beginning of quickening
16-20 weeks
4 positive signs of pregnancy
- Fetal skeleton on x-ray
- Fetal presence on ultrasound
- Auscultation of FHR by doppler (8-12 weeks)
- Examiner palpates fetal movement/outline
4 probable/presumptive signs of pregnancy
- All blood and urine pregnancy tests
- Chadwick’s sign (blue cervix)
- Goodell’s sign (cervical softening)
- Haegar’s sign (uterine softening)
Office visits for pregnancy timing
Once a month until week 28
Every 2 weeks until week 36
Every week until delivery or week 42
What are five examples of aminoglycosides?
Streptomycin
Vancomycin
Clindamycin
Gentamycin
Tobramycin
What routes can aminoglycosides be given?