marine pharma. Flashcards

1
Q

It is a semisynthetic antiviral agent based on the arabinosyl nucleoside isolated from the marine sponge Tethya crypta. The compound shows a prominent therapeutic activity.

A

ARA-A

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2
Q

It is a compound that is found to be a potential antitumour agent during its clinical trials.

A

DIDEMNIN B

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3
Q

It shows the broad-spectrum of anthelmintic activity against the parasitic roundworms, tapeworms, and whipworms.

A

a-KAINIC ACID

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4
Q

It is marketed under the trade name Cytosar by Upjohn pharmaceutical company for the treatment of acute myelogenous leukaemia and human acute leukaemia.

A
  1. ARA -C
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5
Q
  • A series of ________ derivatives isolated from marine cyanobacterium Rivularia firma has shown potential anti-inflammatory activity in the models of carrageenan-induced rat paw oedema.
A

BIO-INDOL

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6
Q

Many cancer treatments, such as chemotherapy, rely on the ____________ of drugs to target and destroy cancer cells.

A

CYTOTOXIN

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7
Q

What do many marine microorganisms produce that may work for their safety and protect them from predators.

A

MARINE TOXINS

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8
Q

Is a potent neurotoxin produced by the pufferfish of the family Tetraodontidae.

A

TETRODOTOXINS

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9
Q

is used as a crude drug in treatment of iodine deficiency states such as goitre.

A

MACROALGAE

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10
Q

Potent neurotoxin, its name derives from Tetraodontiformes.

A

TETRADOTOXINS

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11
Q

The first marine natural product containing guanine and sulfone units?

A

AGELASIDINE A

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12
Q

It is a potent neurotoxin and the best known paralytic shellfish toxin.

A

SAXITOXIN

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13
Q

AN indole alkaloid produced by the marine cyanobacterium Lyngbya majuscula and is known for causing ‘swimmer’s itch’.

A

LYNGBYATOXIN

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14
Q

____ are the B-carboline derivatives that are isolated from sponges and gorgonians.

A

EUDISTOMINS

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15
Q

_____ two sesquiterpene benzonoids derived from the sponge Dysidea avara, that exhibited strong Anti-HIV activity.

A

AVAROL AND AVARONES

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16
Q

______ suplhated polysaccharide mpound extracted from brown algae, which showed activity against HIV and Herpes simplex virus.

A

FUCOIDAN

17
Q

What is a compound chemically related to kainic acid?

A

DOMOIC ACID