Marijuana Flashcards
When and where was cannabis first reportedly used?
Ancient China in the 2800s
Who discovered the psychoactive components of cannabis?
Chinese Emperor Shen Nung
When was cannabis introduced to Canada and America respectively?
1606 (Canada) and 1611 (America)
What is hashish?
A form of sweetmeat made from flower tops.
Who waged the first campaign against all drug use?
Harry Anslinger
When was marijuana considered a narcotic?
1929
What percent of Canadians have used cannabis?
45%
What percent of Canadians have used cannabis in the last year?
12%
What percent of Canadians who have used cannabis in the last year are daily users?
33%
What is the main psychoactive ingredient of cannabis?
Delta-9-tetrahydrocannabinol
When was THC isolated and synthesized?
1964
In the 1970s, what amount of THC would a joint contain?
30mg or around 2%
In the current time, what amount of THC does a joint contain?
60mg or around 4%
What is hashish made out of?
The trichomes of flower buds and leaves, called kief.
What percent of hash is THC?
10%
What percent of hash oil is THC?
40%
Why do people report increasing effects of marijuana despite no experimental evidence proof?
People get better at extracting THC the more experienced at smoking they become. They are able to smoke better and receive a larger dose per hit.
When does peak marijuana blood concentration occur?
It occurs in about 10 minutes.
When does peak marijuana effects occur?
In about 30-60 minutes
How long does marijuana effects last?
About 2-4 hours.
How much stronger are oral doses of THC versus inhaled doses?
Three times as strong.
What is the elimination half life of THC?
Around 5 days.
What is dronabinol (Marinol)?
THC suspended in sesame oil
What is Sativex?
Oral spray of THC
What is nabilone (Cesamet)?
Synthetic THC
Is marinol and cesamet better at anti-nausea relief than smoked marijuana?
Yes
Is marijuana good for pain relief?
Marijuana is useful for pain relief in pain sensitivity, tolderance, and periods of pain relief.
What is the difference between CBD and THC?
CBD is the main “medical” component. It has the pain reducing effects, anti-anxiety, anti-psychotic, and has little effect of drowsiness. It has little effect on learning and memory.
What is the difference between marijuana smoke versus tobacco smoke?
Marijuana smoke has more and higher concentrations of harmful constituents. Smoking a join is 5x the amount of carbon monoxide, 4 times the tar, and 10 times the damage to cell damage in the airways.
What type of memory does THC affect the most?
THC affects short term (working) memory as opposed to long term or reference memory.
How does THC affect memory?
It reduces cholinergic neurotransmission in the hippocampus (a part of the brain rich in cannabinoid receptors)
What study did Lane et al. (2005) conduct and what did it show?
They examined the effects of marijuana on the DMTS performance and found significant impairment and have concluded that it impaired all states of memory incoding as well as neurotransmitters.
What percent of pregnant women use marijuana?
7%
What is the conclusion of teratological effects of marijuana?
It does not produce the same severe effects as with alcohol, but there are some risks (such as low birth weight)