March 2018 Flashcards
- Wilsons likely
a. Baby jaundice 3-6months
b. Corona radiata T2 early in disease
c. High ceruloplasmin bound copper
d. Autosomal dominant
e. Fatty liver
- Wilsons likely
a. Baby jaundice 3-6months too young usually teens
b. Corona radiata T2 early in disease usually basal ganglia causing parkinsonism
c. High ceruloplasmin bound copper low ceruloplasmin high copper
d. Autosomal dominant AR
e. Fatty liver true, mix with high density copper in liver may be normal on CT
- SLE part of diagnostic criteria
a. Pericarditis
b. Peripheral neuropathy
c. Erosive arthropathy
- SLE part of diagnostic criteria
a. Pericarditis true
b. Peripheral neuropathy CNS
c. Erosive arthropathy non erosive
d. MD SOAP BRAIN = criteria for SLE = malar rash, discoid rash, serositis, oral ulcers, arthritis, photosensitivity, blood dyscrasias, renal failure, ANA, immunologic, neurologic
- Xlinked
a. Adrenoleukodystrophy
b. Alexanders
c. Canavan
d. MLD
- Xlinked
a. Adrenoleukodystrophy yes
b. Alexanders
c. Canavan
d. MLD
- FMD doesn’t cause
a. Tinnitis
b. PVD
c. Angina
d. Renal
e. Carotid
**LJS - I think PVD least common of those listed. Tinnitus listed on radiopedia, due to carotid/VA involvement. Rest listed in Robbins, PVD is not in either (though some evidence that it occurs - google)
- FMD doesn’t cause
a. Tinnitis yes but rare, I think rarest only in case series
b. PVD yes but rare
c. Angina yes but rare in case series
d. Renal
e. Carotid
- PAN does not affect
a. Lungs
b. Kidneys
c. Mesenteric vessels
- PAN does not affect
a. Lungs PAN spares lungs classically, similar to MPA but medium vessels affected
b. Kidneys
c. Mesenteric vessels
- SCC tongue which doesn’t cause
a. Marijuana
b. Cocaine
c. HPV
d. Syphillis
e. Alcohol
- SCC tongue which doesn’t cause
a. Marijuana smoking
b. Cocaine doesn’t because you snort it, HTN, perforation
c. HPV yes oral sex
d. Syphillis rare syphilitic leukoplakia
e. Alcohol yes
- Not risk factor for RCC
a. Smoking
b. Alcohol
c. Obesity
- Not risk factor for RCC
a. Smoking yes
b. Alcohol no! lower risk
c. Obesity yes
- Precursor to melanoma
a. Blue naevus
b. Dysplastic naevus
c. Congenital naevus
d. Basal naevus
- Precursor to melanoma
a. Blue naevus
b. Dysplastic naevus yes
c. Congenital naevus
d. Basal naevus
- PML
a. JCV
- PML
a. JCV yes
- Jaundice in pregnancy, most common cause of liver disease in pregnancy
a. Cholestasis
b. Hepatitis
c. Preeclampsia
d. HELLP
b. Hepatitis yes most common cause of jaundice in pregnancy
- Jaundice in pregnancy, most common cause of liver disease in pregnancy
a. Cholestasis 1 in 1000
b. Hepatitis yes most common cause of jaundice in pregnancy
c. Preeclampsia HTN and proteinuria
d. HELLP rare but bad
- Least true regarding circumvallate
a. Abruption
b. IUGR
c. Painless bleeding
d. Fetal death
e. Abnormal tocography
- LW:
11. Least true regarding circumvallate: favoured answer painless bleeding.
a. Abruption: known association
b. IUGR: known association
c. Painless bleeding: not by itself, association with abruption which causes painful bleeding.
d. Fetal death: usually of no consequence
e. Abnormal tocography
- Least correct
a. ADEM follow bacterial infection
b. NMO bilateral optic neuritis
c. Relapsing remitting MS on MRI plaque doesn’t have axonal degeneration
*LW: favour option A.
- Least correct
a. ADEM follow bacterial infection: possible but rare, and most resoruces state viral or post vaccination. ONly case report level of bacterial.
b. NMO bilateral optic neuritis: true
c. Relapsing remitting MS on MRI plaque doesn’t have axonal degeneration: RObbins states Axons are relatively preserved but may be reduced in number. Other resources have stated, they do have axonal degeneration.
- Hirschprungs false
a. More common in females
b. Involves whole colon
c. Bowel obstruction and perforation
a. More common in females more common male
- Hirschprungs false
a. More common in females more common male
b. Involves whole colon
c. Bowel obstruction and perforation
- PXA
a. Involves grey matter and overlying meninges
b. Adults frontal
c. Child brainstem and cerebellum
- PXA
a. Involves grey matter and overlying meninges this dural reaction
b. Adults frontal temproal
c. Child brainstem and cerebellum rare
- Which chondroid lesion crosses physes
a. Chondroblastoma
b. Periostial chondroma
c. EnchondromaLeas
d. CMF
e. Osteochondroma
- Which chondroid lesion crosses physes:
*LW:
Wheeles states: only three tumors may invade physis: chondroblastoma, GCT, and clear cell chondrosarcoma
a. Chondroblastoma rarely may cross physis: probably the best answer
b. Periostial chondroma: periosteal based lesion, so unlikely to cross the actual physical bar.
c. Enchondroma: very unlikely to occur in the epiphysis, occurring most commonly in diaphysis.
d. CMF: unlikely
e. Osteochondroma: exophytic so false.
- PVNS and GCT (Giant cell tumour of tendon sheath) which is false
a. PVNS most common knee
b. GCT most common wrist
c. PVNS and GCT erode bone
d. GCT excision likely to recur
e. PVNS characteristically cause inflammation
e. PVNS characteristically cause inflammation probably this characteristically bleed other answers are all more correct, and is a low grade neoplasm rather than an inflammatory process.
16. PVNS and GCT (Giant cell tumour of tendon sheath) which is false
a. PVNS most common knee: TRUE
b. GCT most common wrist: TRUE
c. PVNS and GCT erode bone: Can do in up to 15%
d. GCT excision likely to recur: TRUE
e. PVNS characteristically cause inflammation probably this characteristically bleed other answers are all more correct
- Post partum diabetes insipidus
a. Lymphocytic hypophysitis
b. Sheehans
- Post partum diabetes insipidus
a. Lymphocytic hypophysitis yes, loss of posterior pituitary bright spot and DI
b. Sheehans massive bleed and necrosis
- Most common with tumor marker
a. YS tumor
b. Seminoma
c. Granulosa cell
- Most common with tumor marker
a. YS tumor aFP
b. Seminoma
c. Granulosa cell
- Most common elderly testicular tumor
a. Lymphoma
- Most common elderly testicular tumor
a. Lymphoma yes
- Most common eldertly germ cell testicular tumor
a. Spermatocytic seminoma
- Most common eldertly germ cell testicular tumor
a. Spermatocytic seminoma yes
- Wilms least correct
a. Bilateral almost always germ line
b. Unilateral is 50% genetic
c. Genetic wilms have nephrogenic rests
b. Unilateral is 50% genetic: this is lease correct as approx. 10% is genetic.
- Wilms least correct
a. Bilateral almost always germ line
b. Unilateral is 50% genetic: this is lease correct as approx. 10% is genetic.
c. Genetic wilms have nephrogenic rests
- Breast least likely in post menopausal
a. IDC
b. LCIS
c. Fibroadenoma
d. Phylloides
e. Papillary
c. Fibroadenoma young
- Breast least likely in post menopausal
a. IDC
b. LCIS
c. Fibroadenoma young
d. Phylloides
e. Papillary
- True regarding juvenile papillomatosis
a. Most commonly presents as palpable mass
b. Nipple discharge
c. Solid lesion on US
d. No increased risk of breast cancer
- True regarding juvenile papillomatosis
a. Most commonly presents as palpable mass: correct
b. Nipple discharge: FALSE - adult papilloma bloody discharge
c. Solid lesion on US: FA:LSE - can have small cysts, pathologically swiss cheese appearance
d. No increased risk of breast cancer: FALSE - increased risk
- Regarding thyroid lesions (which is false)
a. Iodine deficiency associated papillary
b. Radiation is associated with papillary
c. Medullary with MEN worse prognosis than medullary without MEN
d. Anaplastic kills by invasion
e. Hashimotos sometimes assoc with hodgkins lymphoma
**LJS - iodine deficiency is ass/w follicular carcinoma (Robbins p 1095)
Hashimotos ass/w marginal zone B cell lymphoma (NHL) and papillary carcinoma
Rest are true
- Regarding thyroid lesions (which is false)
a. Iodine deficiency associated papillary: FALSE
b. Radiation is associated with papillary: TRUE
c. Medullary with MEN worse prognosis than medullary without MEN: TRUE
d. Anaplastic kills by invasion: TRUE
e. Hashimotos sometimes assoc with hodgkins lymphoma: FALSE - associated NHL
- More likely Hodgkins than NHL
a. Single nodal site
b. Extranodal disease
c. Small bowel mesentery
- More likely Hodgkins than NHL
a. Single nodal site true
b. Extranodal disease NHL
- Complex sclerosing lesion on biopsy
a. No further management, benign
b. Hookwire and open biopsy
c. Hookwire WLE and SNB
- Complex sclerosing lesion on biopsy
a. No further management, benign false
b. Hookwire and open biopsy correct
c. Hookwire WLE and SNB false SNB only if invasive cancer, radial scar is not cancer, DCIS is not cancer