MAOIs Flashcards
1
Q
Drugs
A
- Selective
- Selegiline
- Rasagiline
- Non-selective
- Isocarboxazid
- Phenelzine
- Tranylcypromine
2
Q
Mechanism of action
A
- Selective
- Inhibits monoamine oxidase B, increasing dopamine levels
- Non-selective
- Inhibits monoamine oxidase A and B, increasing serotonin, dopamine and norepinephrine
3
Q
Contraindications
A
- Cerebrovascular disease
- Manic phase
- Phaeochromocytoma
- Severe caediovascular disease