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1. Top Drawer Meds+ > Mannitol > Flashcards

Mannitol Flashcards

1
Q

Mannitol dose for ICP/IOP pressure reduction

A

0.5 - 2 g/kg

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2
Q

Mannitol dosing for Kidney revascularization/flushing

A

12.5 - 25 gm per surgeon request

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3
Q

Mannitol MoA

A
  • ↑ Osmotic diuresis by ↑ osmotic pressure of the glomerular filtrate
  • Inhibits H2O, Na+, K+ reabsorption
  • ↓ ICP/IOP by osmosis of fluid in brain paranchyma into intravascular space

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4
Q

Mannitol onset

A

Diuresis: 1-3 hrs
↓ ICP/IOP: 15-30 minutes

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5
Q

Mannitol Duration

A

1.5 - 6 hrs

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6
Q

Mannitol Metabolism/Elimination

A

Metabolism: Minimally liver → Glycogen
Elimination: Renally (unchanged)

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7
Q

Mannitol Dosage form?

A
  • 10% (500mL, 100mg/mL)
  • 20% (500mL, 200mg/mL)
  • 25% (50mL, 250mg/mL)

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1. Top Drawer Meds+ (58 decks)

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