Managing Skin Disorders In Systemic Disease

Question 1

38yo female, photodistributed rash with new onset of fever, arthritis and fatigue. No new medications
Which of the following investigations is indicated: urinalysis, vitamin C, lipid panel, HbA1c?

Answer 1

Urinalysis -

Question 2

Which of the following conditions are not associated with: new rash of face, chest, upper back and dorsal hands (heliotrope rash, gottrons papules, shawl sign) with difficulty getting up the stairs?
Diabetes mellitus, digital ischaemia, malignancy, interstitial lung disease

Answer 2

Diabetes mellitus

Question 3

Which of the following signs are associated with chronic kidney disease: corkscrew hairs and perifolliocular purpura, calciphylaxis, Casals necklace, periocular purpura

Answer 3

Calciphylaxis

Question 4

Which of the following is true regarding itch in the absence of a rash?
Itch in the absence of a rash indicates malingering or a psychogenic aetiology
Chronic rubbing and scratching may cause the appearance of nodules
Drugs are an unlikely culprit in the absence of a rash
Iron deficiency, not iron overload cause itch

Answer 4

Chronic rubbing and scratching may cause the appearance of nodules

Question 5

Which of the following is correct regarding Drug Reaction with Eosinophilia and Systemic Symptoms?
The brain is not among organs targeted
The complications of erythroderma account for most fatalities
Characteristic features on biopsy allow diagnostic confirmation
Fulminant liver failure may occur

Answer 5

Fulminant liver failure

Question 6

Which of the following is a manifestation of sarcoidosis?

Lupus vulgaris
Lupus profundus
Lupus pernio
Lupus tumidus

Answer 6

Lupus pernio

Question 7

Which of the nail changes is not associated with chronic liver disease?
Clubbing
Muehrcke’s lines
Terry’s nails
Half and half nails

Answer 7

Half and half nails

Question 8

Which of the following conditions is not associated with inflammatory bowel disease?
Pyoderma gangrenosum
Dermatitis herpetiformis
Hidradenitis suppuritiva
Orofacial granulomatosis

Answer 8

Dermatitis herpetiformis

Question 9

Which of the following are not a manifestation of malignancy?
Lues maligna
Pyoderma gangrenosum
Acanthosis nigricans
Dermatomyositis

Answer 9

Lues maligna

Question 10

HIV seroconversion may manifest in which of the following ways?
Urticaria
Erythema multiforme
Morbilliform rash
All of the above

Answer 10

All of the above

Question 11

Which of the following conditions may be a manifestation of underlying Acromegaly?
Cutis gyrata verticis
Xerosis
Perforating disorder
Erythema gyratum repens

Answer 11

Cutis gyrata verticis

Question 12

Which of the following statements are true regarding the skin in systemic disease?
Comprehensive diagnostic investigations must be performed in each rash to avoid missing underling systemic conditions, as history is not specific nor sensitive
Spot diagnoses indicate good clinical skills
Dermatological diagnostic skills are desirable, but not essential, as the option to take a skin biopsy allows a histopathologist to make the diagnosis
Management of multi-systemic diseases can be undertaken by several different specialties concurrently

Answer 12

Management of multi-systemic diseases can be undertaken by several different specialities concurrently

Question 13

Which of the following features renders cutaneous graft vs host disease (cGVHD) a more likely than a drug as the cause of this rash?
Diarrhoea
Acral involvement
Facial involvement
All of the above

Answer 13

All of the above