Managing Skin Cancer Tutorial Flashcards

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1
Q

Which of the following is false regarding melanoma?

It can arise in the eyes
Redhair is a risk factor
Pre-existing nevi are a risk factor
Causes >75% of skin cancer deaths

A

Pre-existing nevi are not a risk factor
>50% of melanomas arise without pre-existing nevus
Atypical nevi and >100 nevi are considered a risk factor

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2
Q

Which of the following is true regarding the pathogenesis of melanoma?

A

CDKN2A encodes p16, a tumour suppressor

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3
Q

Which of the following statements if true?

x

A

Superficial spreading melanoma is most common variant in pale skin types

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4
Q

Which of the following is true regarding melanoma detection?

A

Melanoma and basal cell carcinoma may appear grossly similar

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5
Q

Which of the following investigation of melanoma is correct?

A

BRAF mutation status can inform prognosis and treatment decision

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6
Q

Which of the following is true regarding keratinocyte carcinoma / dysplasia?

A

Keratinocyte carcinomas are more common in men than in women

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7
Q

Which of the following is false about Basal cell carcinoma (BCC)?

A

BCC never metasises, and thus treatment is usually desirable rather than essential

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8
Q

Which of the following is true regarding basal cell carcinoma management?

A

Vismodegib may be used for unresectable BCC

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9
Q

Which of the following is correct regardin the cutaneous squamous cell carcinoma (SCC)?

A

May be difficult to distinguish from keratoacanthoma

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10
Q

Which of the following is true regarding myocosis fungoides?

A

Any pruiritus is usually mild

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11
Q

Which of the following statements if true regarding Kapsoi sarcoma?

A

It may appear as a pink patch of a polyp

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12
Q

Which of the following statements is false regarding Merkel cell carcinoma?

A

Arises from cancerous merkel cells = false

MCC shares structural features with merkel cells, not derived from this

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13
Q

Which of the following is not a treatment option for actinic keratoses?

A

Radiation therapy

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14
Q

Which of the following represents (relative) low risk features in squamous cell carcinoma?

A

Absence of perineural invasion

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15
Q

Which of the following statements is false regarding cutaneous T-cell lymphoma?

A

In mycosis fungoides, early aggressive treatment is indicated to prevent progression = false

Early aggressive therapy does not improve survival

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