Managing pain and Behavior guidance (Chapter 12) Flashcards

1
Q

Why are infants and children more sensitive to pain?

A

Ascending pathways intact allowing full transmission of pain. Descending pathways modulating pathways poorly developed and unable to attenuate pain and do not have cognitive skills to modulate pain.

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2
Q

Theory of pain

A

descending pathway modify pain gate-activation of large fiber sensory neurons can modify pain perception.

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3
Q

Wong-baker FACES pain scale

A

Self reported pain w/faces validated for 3+

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4
Q

Visual Analogue pain scale

A

0-10 pain scale for 6+ on a numerical line.

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5
Q

Observational pain scale (FLACC)

A

Provider observes face, legs, arms, crying, consolability scale (FLACC) with a 0-2 scale.

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6
Q

Why does sucrose work to help manage pain?

A

Sucrose has same pathway as opioids; efficacy wanes at 6 months.

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7
Q

Benzocaine as a topical anesthetic

A

Up to 20%
Ester
Not for age 2 and under

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8
Q

Lidocaine as topical

A

Amide
5-10%
as ointment, patch or spray

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9
Q

Compound local topical anesthetics

A
High doses 
Tetracaine
lidocaine
benzocaine
prilocaine 
phenylephrine  
Must consider systemic absorption when calculating total amount of anesthetic dosage administered.
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10
Q

What is the preservative in local anesthetics with epinephrine?

A

Bisulphate.

Use anesthetic w/o epinephrine for allergies to bisulphate

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11
Q

Articaine is metabolized where?

A

Liver and plasma.

Lidocaine metabolized by P450 cytochrome enzymes.

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12
Q

Which anesthetic has no epinephrine?

A

Mepivacaine.

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13
Q

Rule of 25

A

Can use 1 cartridge of any marked local anesthetic for every 25 pounds of body weight

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14
Q

Where is IAN foramen in children compared to adults?

A

More inferior and posterior in young children

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15
Q

What is phentolamine mesylate used for and MOA?

A

Local anesthetic reversal agent. Causes vasodilation by reversible nonselective alpha-adrenergic antagonist moving local anesthetic away from site for metabolism

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16
Q

What are the biphasic clinical manifestation of local anesthetic toxicity.

A

Initial excitatory reaction: circumoral tingling, dizziness, tinnitus, increased HR and BP
Later depressive reaction: drowsiness, loss of consciousness, seizure, cardiovascular collapse.

17
Q

Ibuprofen MOA and contraindications

A

NSAID
First line for pain
Inhibits cyclooxygenase thereby impairing transformation of arachidonic acid to prostaglandins, prostacyclin and thromboxanes

18
Q

Acetaminophen MOA and contraindications

A

MOA unknown
Thought to inhibit cyclooxygenase enzyem
Antipyretic inhibits of hypothalamic heat regulating center

19
Q

Asprin

A

Not recommended for children

20
Q

Ibuprofen Doses

A

4-10mg/kg q 6-8 hours

40mg/kg/day

21
Q

Acetaminophen doses

A

10-15mg/kg q 4-6hours

90mg/kg/day, no more than 5 doses per day

22
Q

Naproxen Doses

A

5-7mg/kg q 8-12 hours

600mg/24 hours

23
Q

Is codeine recommended for children

A

NO

24
Q

Acetaminophen with hydrocodone doses

A

0.1-0.2mg/kg/dose of hydrocodone q 4-6 hours

25
Q

Acetaminophen with oxycodone doses

A

0.05-0.2mg/kg/dose of oxycodone q 4-6 hours

26
Q

Naproxen MOA and contraindications

A

Reversibly inhibits cyclooxygenase-1 and 2,

Not recommended for any under 12

27
Q

Opioids MOA and contraindications

A

Hydrocodone, oxycodone
Binds to opioid receptors in CNS causing inhibition of ascending pain pathways
CNS depression
Metabolized by liver cytochrome P450, CYP3A4, CYP2D6
Cytochrome inhibitors increase longevity of drugs in system (macrolide, proton pump inhibitors, SSRI, St. Johns warts, echinacea.

28
Q

What opioids can be given to patients that are poor/rapid metabolizers for pain management?

A

Morphine and hydromorphone-are not metabolized by CYP2D6 enzymes.