Management of patients with Diabetes Mellitus Flashcards
Diabetes Mellitus
Group of metabolic diseases characterized by high blood glucose level and the inability to produce and/or use insulin
Diabetes Mellitus
Two Major Types:
(2)
Type I: Insulin-dependent diabetes mellitus (IDDM)
Type II: Non-insulin-dependent diabetes mellitus (NIDDM)
Other Types
(2)
Type III – Other types of diabetes (drugs, pancreatic or hormonal disease)
Gestational Diabetes Mellitus (GDM) –Seen in pregnant patients
Diabetes Mellitus - Facts
* Affects 30.3 million Americans, or –% of the population (2017).
9.4%
Of the 30.3 million Americans, 23.1 million were diagnosed, and – million were undiagnosed.
7.2
About 5% of American people with diabetes are estimated to have Type – diabetes.*
1
In 2015, an estimated – million “new cases” of diabetes were diagnosed among U.S. adults aged 18 years or older.
1.5
More than half of these new cases were among adults aged
45 to 64 years.
— leading cause of death in U.S (2015).
Seventh
Systemic effects
(6)
Kidney disease (Nephropathy),
High blood pressure,
Retinopathy,
Neuropathy,
Stroke,
Foot complications etc.,
Leading cause of — in U.S.
blindness
Type I diabetes occurs when the
immune system destroys the insulin-producing beta cells of the
pancreas resulting in decreased or absent circulating insulin
1
It is usually diagnosed in children and young adults, and was previously known as
Juvenile diabetes.
1
More common in
adolescents (peak age at diagnosis is around14 years).
May develop in adults.
1
Only –% of diabetic patients in the United States have this form of the disease.
5
1
Requires …
exogenous insulin
IDDM-Signs and Symptoms
(7)
- Sudden onset of symptoms
- Age of onset: 15 years
- Polydipsia
- Polyuria
- Polyphagia
- Wt. Loss
- Dry mouth
2
* Usually seen in —
adults
2
– % of diabetic population.
95
2
3 Cardinal abnormalities:
(3)
- Resistance to insulin action in peripheral tissues
- Defective Insulin secretion
- Increased liver Glucose production
2
Clinical onset —.
slow
2
Blood sugar levels much more stable so — uncommon.
Ketoacidosis
NIDDM - Signs and Symptoms
(7)
- Gradual onset of symptoms
- Age of onset: 40 years
- Slight wt. Loss/ gain
- Nocturnal urination
- Blurred / decreased vision
- Paresthesias / loss of sensation
- Postural hypotension
Laboratory Investigations for Monitoring Diabetes
Fasting Plasma Glucose (FPG)
— or more occasions
Normal:
Prediabetes:
Diabetes:
2
70 to 110 mg/dl
110 mg/dl to 125 mg/dl
126 mg/dl or higher