Management Of Chronic Pain Flashcards
0
Q
Describe the path of pain
A
Painful stimulus, skin, ad or c fibre, lamina 1 of spinal cord, lamina 5 of spinal cord, thalamus, somatosensory cortex
1
Q
Define pain
A
An unpleasant sensory and emotional experience associated with actual tissue damage or described in terms of such damage
2
Q
Describe neuropathic pain
A
Burning, shooting, tingling
Allodynia, hyperalgesia
3
Q
Name 5 causes of neuropathic pain
A
Shingles, post hermetic neuralgia Diabetic neuropathy Amputation Surgery Trauma
4
Q
How is neuropathic pain managed
A
Tricyclics antidepressants (amitriptyline) Anticonvulsants (gabapentin) Opioids (morphine) NMDA antagonists (ketamine) Sodium channel blockers (lignocaine) Capsaicin GABA agonists (baclofen)
5
Q
What causes pain in Cancer survivors?
A
Post surgical pain Chemotherapy induced painful peripheral neuropathies Chronic graft vs host disease Radiation induced pain syndromes Hormonal therapy and arthralgias
6
Q
What causes pain after injury?
A
Peripheral sensitisation- reduction in the threshold of peripheral afferent nociceptors
Central sensitisation- increased excitability of spinal neurones
Rewiring in the spinal cord
Changes in the brain
