Mammo reg Flashcards
BSE involves
Looking & feeling for changes in the breast
CBE is a check of the breast by who?
Qualified healthcare professional
ACS recommends women 20 & older perform BSE
Every month
Women 20-39 should have a CBE how often?
Every 3 years
Women 40 & older should have screen mammo & CBE how often?
Every year
Thorough clinical exam will:
Locate lumps/suspicious areas, Nipple changes, Skin changes in breast, Lymph nodes n armpit & above collarbone
Medical/family history provides:
Symptoms & risk factors for breast cancer & benign breast conditions; questions about other health problems
Effectiveness & sensitivity of mammogram ——- with age.
Increases
Average glandular dose of screen-film mammogram with grid
0.1-0.2 rad
Biggest risk factor for breast cancer
Gender
High risk factors
Age, Age, Genes-brCA1&2…, Close blood relative, Personal hx breast ca
Moderate risk factors
1st degree relative w breast ca, Atypical hyperplasia on biopsy, High rad dose to chest, High bone density after menopause
Minor risk factors
No child bearing or after 30, Not breast feeding , Early menarche/late menopause, Post menopausal obesity, Long term use HRT/contraceptive, Alcohol consumption, Obesity
Examples of benign breast disease
Painful cyst Painful cyst, Nipple discharge, Only detected on mammo:
Ca+, circumscribed tumors, lesions, asymmetric densities, skin thickening
Ca+
circumscribed tumors
2 main classes breast cancer
Ductal, Lobular
90% all cases of breast cancer?
Ductal carcinoma
Stage 0 carcinoma is confined to
duct (DCIS)
Cancer has spread from ducts into surrounding stromal tissue & possibly pectoral fascia/ muscle
Invasive/infiltrating Ductal carcinoma
Lobular carcinoma accounts for — to —-% all breast cancers
5-10
Not seen on mammo in 50% cases
abnormal cells grow w/in lobules not penetrating lobule walls
Difficult to perceive on mammo
may show as spider web or cause skin retraction
Other breast carcinomas account for less than 10% & have —– prognosis than infiltrating Ductal/lobular cancers
Better
Single most effective tool in detection breast cancer
Mammogram
Describe malignant asymmetric density on mammogram
Speculated/stellate lesion w solid central tumor & radiating structures
Malignant circumscribed lesions
Ill-defined & high density radiopaque, except few rare are low density
Ductal ca+
Granular or casting type Ca+ & usually appear in clusters
2 types mammography screening
Conventional-analog, Digital-w cassette or wo
2 types digital detectors
Direct, indirect (cassette less)
Uses high frequency sound waves & based on pizoelectric effect
U/S
Highly vascular lesions are often
Malignant
MRI based on magnetic properties of —– ——- in the body.
Hydrogen atoms
——— ——— ———– involves injecting contrast while breast is under compression
Contrast digital mammography
Dual energy subtraction used for what 3 reasons?
Enhance masses, Eliminate obscuring structures
Separate soft tissue from contrast or Ca+ deposits
3 types nuclear medicine studies used w/mammography
PET, Breast scintigraphy
Lymphoscintigraphy
PET imaging uses —— based on the need that cancer cells have for sugar
FDG-fluorodeoxyglucose
Breast scintigraphy aka ——- Or by the trade name ——-.
Scintimammography, Miraluma
Breast scintigraphy uses what isotope? What kind of camera?
Tc-99m sestamibi, Gamma
_______ can be used to reduce blind dissection of axillary nodes & resultant side effects
Lymphoscintigraphy
Lymphoscintigraphy aka
Sentinel node mapping
Lymphoscintigraphy uses injection of radio isotope where?
Around the tumor
Principle behind Lymphoscintigraphy
First node sentinel node, receives drainage from a tumor & can be used to predict presence or absence of tumor in remaining nodes
Technology that uses 11 low dose images taken during 7-11 seconds; x-ray tube rotates 50 deg. arc around breast
Digital tomosynthesis
CT laser mammography based on what principle?
angiogenesis
______ involves removal of content of cyst and is often performed under u/s guidance
cyst aspiration
FNA ideal for cyst eval. and aspiration. Uses ___ to ____ gauge needle
22-25
which breast intervention usually requires a cytotechnologist eval of sample
Fine needle aspiration
3 treatments for breast cancer
surgery,surgery, drugs (chemo/hormone therapy), radiation therapy
_________ removes breast tissue and some of underarm lymph nodes
modified radical mastectomy
_______ is removal of entire breast
mastectomy
which mastectomy removes entire breast, lymph nodes, and chest wall muscles?
radical mastectomy (RARELY PERFORMED)
most breast conserving surgery
lumpectomy
two common types of flap techniques
TRAM, latissimus dorsi flap
more common form of radiation treatment
external beam
internal beam radiation usually lasts ______ to ____ days and can begin _____ after surgery.
7-9; day
how long does external beam radiation usually last? and how long after surgery can it begin?
5-7 weeks; 1 month after surgery
which of 3 treatments is systemic treatment?
chemotherapy (affects all cells of body)
common antiestrogen drug tamoxifen
common antiestrogen drug
tamoxifen
antiestrogen drug less toxic than tamoxifen?
raloxifene
SERMS
selective estrogen receptor modulators
3 uses of hormonal treatment using SERMS
prevent estrogen from latching onto tumor cell receptors, shrink/stop recurrence of breast cancer
lower risks breast cancer in postmenopausal women
2 newer flap techniques
DIEP; gluteal free
____ used to evaluate nipple discharge
duct expansion
_____ is prelude to surgical biopsy & necessary if stereo localization not available
preop localization
pre op localization can be performed w/which modalities
mammo
______ biopsy recommended with lesions that are difficult to approach or close to breast surface.
open surgical
which intervention can be used to confirm finding of FNA or FNB
open surgical biopsy
_____ uses 22-25 g needle to remove cell samples from nonpalpable lesions for cytological analysis.; often used with stereo localization
FNB-fine needle biopsy
Method of locating nonpalpable lesions by using computer to calculate precise location.
Stereotactic breast localization/biopsy
Intensity of x-ray beam is less on _____ side of tube due to _____ effect.
anode; anode heel
Cathode side of x-ray tube is always directed to the _______
the thickest area of the breast.
Material used for exit port or window of x-ray tube
borosilicate glass or beryllium (Be)
Why is the exit window of x-ray tube NOT made of regular glass?
regular glass window would harden the emerging beam by eliminating soft characteristic radiation
KVp range will depend on ______ material available
target/filtration
How does Kvp range affect contrast?
contrast higher in thinner breast; lower in thicker breast
Increased kvp allows ____ dose but reduced _____
lower; contrast
The ______-_____ combination will essentially shape the x-ray beam
providing the necessary kvp range to penetrate dense/fatty breasts.
older mammography generators were _______.
three phase
All modern generators are _________.
high frequency generators
molybdenum target with _____ mm molybdenum filtration or 0.05 mm rhodium filtration.
0.03
rhodium target with _____mm rhodium filtration
0.025
molybdenum and tungsten alloy target with ____ or ____ filtration
molybdenum; rhodium
molybdenum and rhodium alloy target with _____ or _____ filtration
molybdenum; rhodium
tungsten target and _____ or rhodium filtration (some digital units)
silver
Flat surface of compression paddle must be ____ to IR
parallel
Chest wall of compression paddle should not extend beyond chest wall edge of IR by more than ____% of SID
2
Lip of compression paddle should have a _____ angle at the chest wall
right
lip along the chest wall should be —to—- cm in height
2-4
(yes no) A shadow of vertical edge of compression paddle should not be visible on the image
TRUE
Recommended focal spot sizes in mammography are ___ (smaller/routine work) & ____(magnification).
0.4mm; 0.15mm
Most commonly used focal spot size for routine work
0.3mm
most commonly used focal spot size for magnification
0.1mm
Size and shape of focal spot size are determined by what 3 things?
size and shape electron beam hitting anode, design and relationship filament coil to focusing cup
angle of anode
In mammography the aim is to have the _____ focal spot with the ____SID
smallest; longest
SID in mammo is fixed
50-80cm
_____ cassette systems are used in mammography to provide the best spatial resolution
single-screen
AEC controls length of exposure and determines___ of the final image
density
Two types AEC found in modern mammography
ionization chamber; phototimer