Mammary neoplasia

Question 1

How frequent are mammary tumors in cats

Answer 1

Mammary tumors are the third most common feline tumor after skin and hematopoietic tumors

Question 2

Which breeds seem predisposed to mammary tumors

Answer 2

DSH and Siamese cats appear to have an elevated risk for mammary tumors
- Siamese cats are significantly younger at the time of diagnosis

Question 3

What are the most common histologic diagnoses for feline mammary tumor

Answer 3

The most common histologic diagnoses are hormone-receptor independent adenocarcinomas

Question 4

What chemotherapeutic drugs are commonly used as adjuvant therapy

Answer 4

Doxorubicine (1mg/kg, IV, q21 days for five treatments) given postoperatively starting at the time of suture removal
- doxorubicin should be used with care because of the potential risk of nephrotoxicity in cats

Mitoxantrone (6mg/m2, IV every 21 days for four doses) may be a suitable alternative for cats with compromised renal function