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Gyne > Malignant Tumors > Flashcards

Malignant Tumors Flashcards

1
Q

2nd most common malignancy of the female genital tract

A

Ovarian cancer

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2
Q

Ovarian cancer risk is decreased with
_______use?

A

Ocp use

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3
Q

First degree relative is?

A

Mother, sister, daughter of an affected individual(5% increase in risk)

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4
Q

Second degree relative is?

A

Maternal or paternal aunt or grandmother

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5
Q

This type of ovarian tumor comprises 2/3 of all ovarian tumors?

A

Epithelial ovarian tumor

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6
Q

Most common ovarian tumor?

A

Epithelial

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7
Q

In low grade serous ovarian carncer what pathway has an imp role in its pathogenesis?

A

MAP kinase pathway

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8
Q

The tumor protein p53 (TP53) gene is mutated in over 96% of cases in?

A

High grade serous ovarian cancer

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9
Q

Hgsoc arise from?

A

Fimbriated end of F.T.

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10
Q

Lgsoc arise from?

A

Serous borderline, endometriosis or ovarian surface epithelium

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11
Q

Mucinous ovarian tumors resemble ?

A

Endocervix
Intestinal cells

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12
Q

Benign type mucinous ovarian tumors are found in?

A

Reproductive years

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13
Q

Malignant mucinous ovarian tumors are found in ?

A

30 -60yrs of age

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14
Q

Mucinous ovarian carcinoma occurs due to mutation in which genes?

A

KRAS
HER 2 amplification

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15
Q

Endometriosis ovarian cancer occurs in what age group?

A

Women in their 40’s

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16
Q

This type of cancer is seen in conjunction with ovarian endometriosis and endometriosis.
It’s a bilateral for malignant type?

A

Endometriosis ovarian cancer

17
Q

Brenner tumor resembles what kind of cells?

A
  1. Transitional epithelium of bladder
  2. Walthard nests of the ovary
18
Q

M1

A

Irregular solid tumors

19
Q

Presence of ascites?

A

M2

20
Q

At least 4 Papillary structures

A

M3

21
Q

Irregular multi- ocular solid tumor with the largest diameter> 100mm

A

M4

22
Q

Strong blood flow( color score4)

A

M5

23
Q

B1

A

Unilocular cyst

24
Q

Presence of component where the largest solid component has a largest diameter<7mm

A

B2

25
Q

Presence of acoustic shadows

A

B3

26
Q

Smooth multiocular tumor with the largest diameter<100mm

A

B4

27
Q

No blood flow colour score 1

A

B5

28
Q

Which tumor marker is increased in 80% of epithelial ovarian carcinoma

A

CA 125

29
Q

How much CA125 is considered increase?

A

More than 35U/ml

30
Q

Symptoms of ovarian cancer?

A

Abdominal pain
Bloating feeling
Urinary urgency
^Abdominal size
Palpable pelvic mass

Gyne (1 decks)

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