Malignant Eyelid Tumors Flashcards by rie Unknown

Four layers of eyelids:
SSTP

Skin and subcutaneous tissue including its adnexa
Striated muscle
Tarsus with the meibomian glands
Palpebral conjunctiva

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True or False: Malignant tumors can’t arise from each of the eyelid layers.

False; Malignant tumors can arise from each of the eyelid layers.

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Most eyelid tumors are of: “_____________” (mostly epidermal)

Cutaneous origin

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Malignant eyelid tumors can be divided:

Epithelial tumors
Melanocytic tumors

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The most common malignant eyelid tumors on Caucasians

Basal cell carcinoma

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The most common malignant eyelid tumors on Asians

Sebaceous gland carcinoma

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Different Types of Malignant Eyelid Tumors:
(NSS-MMK)

Nodular Basal Cell Carcinoma
Sclerosing Basal Cell Carcinoma
Squamous Cell Carcinoma
Meibomian Gland Carcinoma
Melanoma
Kaposi Sarcoma

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The most common type of cancer to occur on the eyelid.

Nodular Basal Cell Carcinoma

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Nodular Basal Cell Carcinoma usually appears on the _______ eyelid or near the inner fold of the eye as a firm, ______ nodule.

lower; pearly

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The lesion in Nodular Basal Cell Carcinoma might be:

1.Early Nodular Basal Cell Carcinoma
2. Advanced Nodular Basal Cell Carcinoma

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Pair the following:

1.Early Nodular Basal Cell Carcinoma
2. Advanced Nodular Basal Cell Carcinoma

a. shows slow progression
b. shows shiny, indurated nodule

1B, 2A

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The lesion in Sclerosing Basal Cell Carcinoma might be:

a. Early Sclerosing Basal Cell Carcinoma
b. Advance Sclerosing Basal Cell Carcinoma

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identify if it’s early sclerosing basal cell carcinoma or advance sclerosing basal cell carcinoma.

shows indurated plaques with loss of lashes

Early Sclerosing Basal Cell Carcinoma

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identify if it’s early sclerosing basal cell carcinoma or advance sclerosing basal cell carcinoma.

Margins impossible to delineate

Advance Sclerosing Basal Cell Carcinoma

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identify if it’s early sclerosing basal cell carcinoma or advance sclerosing basal cell carcinoma.

May mimic chronic blepharitis

early sclerosing basal cell carcinoma

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identify if it’s early sclerosing basal cell carcinoma or advance sclerosing basal cell carcinoma.

shows spreads radially beneath normal epidermis

advance sclerosing basal cell carcinoma.

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Second most common eyelid malignancy

Squamous Cell Carcinoma (SCC)

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Malignant epidermal carcinoma arising from the squamous cell layer of the skin epithelium

Squamous Cell Carcinoma (SCC)

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True or False:

Squamous Cell Carcinoma (SCC): Less than 6% of malignant eyelid neoplasms

False; Less than 5% of malignant eyelid neoplasms

Squamous Cell Carcinoma (SCC)

•Ocular and periocular region, it can affect the:
(CCE)

Conjunctiva, Cornea, Eyelid skin

The lesion in Squamous Cell Carcinoma might be:

Nodular Squamous Cell Carcinoma
Ulcerative Squamous Cell Carcinoma

identify what lesion in squamous cell carcinoma:
hard, hyperkeratotic nodules, may develop crusting fissures.

Nodular Squamous Cell Carcinoma

identify what lesion in squamous cell carcinoma:
- red base, borders sharply defined, induratedand elevated

Ulcerative Squamous Cell Carcinoma

Give 5 risks in Squamous Cell Carcinoma

•Aging
•Longstanding ultraviolet radiation exposure
•Oil derivatives and arsenic exposure
•Cigarette smoke exposure
•Human Papilloma Virus infection (HPV)
•Human Immunodeficiency Virus infection (HIV)
•Xeroderma pigmentosum
•Actinic keratosis (AK)
•Squamous intraepithelial neoplasia (Bowen’s disease)
•Albinism
•Old burns
•Chronic ulcers
•Immunosuppression

Give the 6 Symptoms of Squamous Cell Carcinoma

•Bleeding •Pain •Pruritus, irritation •Enlarging lesion •Ulceration •Crusting lesion

third most common eyelid malignancy

Meibomian Gland Carcinoma

Meibomian Gland Carcinoma is also known as

Sebaceous Gland Carcinoma

True or False: Meibomian Gland Carcinoma is not a rare aggressive tumor with 10% mortality

False; it is very rare

Common location of Meibomian Gland Carcinoma

Upper Lid

Meibomian Gland Carcinoma: ______% of eyelid malignancy

1-5.5%

Meibomian Gland Carcinoma may arise from the:

Meibomian Gland Gland of Zeiss Glands associated with the Caruncle

Which of the following statements describes the Melanoma the best: a. not a rare form of eyelid tumor but the most lethal primary skin tumors b. >1% of eyelid malignancies c. These tumors are pigmented and are highly likely to metastasize, even if they're small. d. both b and c e. none of the above

C; because melanoma is a rare form of tumor, <1% of eyelid malignancies

The following are characteristics of Melanoma, except: a. Often present as a dark b. Variable pigmented nodule or plaque c. Irregular notched borders d. no exception

Give 5 risks of Melanoma:

Sunlight exposure Genetic predisposition Environmental Mutagens Aging Treatment involves Aggressive surgery (complete excision) Incisional or excisional biopsy (diagnosis) Potentially radiation

It is a red to pink conjunctival tumor and a blue to purple eyelid tumor

Kaposi Sarcoma

Vascular tumour commonly occurring in with AIDS

Kaposi Sarcoma

Very Sensitive to radiotherapy

Kaposi Sarcoma

Risk factors of Kaposi Sarcoma:

-HIV -AIDS -Immunocompromised patient - Elderly Patient (slowly progressive)

The lesion in Kaposi Sarcoma might be:

a. Early Kaposi Sarcoma b. Advanced Kaposi Sarcoma

Kaposi Sarcoma lesion that shows pink, red-violet lesion

Early Kaposi Sarcoma

Kaposi Sarcoma lesion that might be ulcerate and bleed

Advanced Kaposi Sarcoma

Diagnosis of Kaposi Sarcoma

-Skin and lymph nodes should be examined -Blood should be tested for HIV, lymphocytes, and other opportunistic disease -in patients with a history of Kaposi's: incisional biopsy for presumptive diagnosis

Treatment of Kaposi Sarcoma (Fill in the blanks) Complete removal at biopsy (_______ ________ __________)

Small Kaposi's Sarcoma

Treatment of Kaposi Sarcoma (Fill in the blanks) Incision Biopsy (________ and _______ _______)

Large and multifocal tumors

Kaposi Sarcoma treatment:

-complete removal at biopsy (Small Kaposi's Sarcoma) -Incision Biopsy (Larger and multifocal tumors) -chemotherapy -radiation therapy -avoid any treatment that would further suppress the patient's immune system (HIV-AIDS related Kaposi sarcoma)