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Ocular Disease (Eyelids) > Malignant Eyelid Tumors > Flashcards

Malignant Eyelid Tumors Flashcards

1
Q

Four layers of eyelids:
SSTP

A

Skin and subcutaneous tissue including its adnexa
Striated muscle
Tarsus with the meibomian glands
Palpebral conjunctiva

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2
Q

True or False: Malignant tumors can’t arise from each of the eyelid layers.

A

False; Malignant tumors can arise from each of the eyelid layers.

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3
Q

Most eyelid tumors are of: “_____________” (mostly epidermal)

A

Cutaneous origin

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4
Q

Malignant eyelid tumors can be divided:

A

Epithelial tumors
Melanocytic tumors

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5
Q

The most common malignant eyelid tumors on Caucasians

A

Basal cell carcinoma

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6
Q

The most common malignant eyelid tumors on Asians

A

Sebaceous gland carcinoma

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7
Q

Different Types of Malignant Eyelid Tumors:
(NSS-MMK)

A

Nodular Basal Cell Carcinoma
Sclerosing Basal Cell Carcinoma
Squamous Cell Carcinoma
Meibomian Gland Carcinoma
Melanoma
Kaposi Sarcoma

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8
Q

The most common type of cancer to occur on the eyelid.

A

Nodular Basal Cell Carcinoma

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9
Q

Nodular Basal Cell Carcinoma usually appears on the _______ eyelid or near the inner fold of the eye as a firm, ______ nodule.

A

lower; pearly

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10
Q

The lesion in Nodular Basal Cell Carcinoma might be:

A

1.Early Nodular Basal Cell Carcinoma
2. Advanced Nodular Basal Cell Carcinoma

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11
Q

Pair the following:

1.Early Nodular Basal Cell Carcinoma
2. Advanced Nodular Basal Cell Carcinoma

a. shows slow progression
b. shows shiny, indurated nodule

A

1B, 2A

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12
Q

The lesion in Sclerosing Basal Cell Carcinoma might be:

A

a. Early Sclerosing Basal Cell Carcinoma
b. Advance Sclerosing Basal Cell Carcinoma

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13
Q

identify if it’s early sclerosing basal cell carcinoma or advance sclerosing basal cell carcinoma.

shows indurated plaques with loss of lashes

A

Early Sclerosing Basal Cell Carcinoma

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14
Q

identify if it’s early sclerosing basal cell carcinoma or advance sclerosing basal cell carcinoma.

Margins impossible to delineate

A

Advance Sclerosing Basal Cell Carcinoma

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15
Q

identify if it’s early sclerosing basal cell carcinoma or advance sclerosing basal cell carcinoma.

May mimic chronic blepharitis

A

early sclerosing basal cell carcinoma

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16
Q

identify if it’s early sclerosing basal cell carcinoma or advance sclerosing basal cell carcinoma.

shows spreads radially beneath normal epidermis

A

advance sclerosing basal cell carcinoma.

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17
Q

Second most common eyelid malignancy

A

Squamous Cell Carcinoma (SCC)

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18
Q

Malignant epidermal carcinoma arising from the squamous cell layer of the skin epithelium

A

Squamous Cell Carcinoma (SCC)

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19
Q

True or False:

Squamous Cell Carcinoma (SCC): Less than 6% of malignant eyelid neoplasms

A

False; Less than 5% of malignant eyelid neoplasms

20
Q

Squamous Cell Carcinoma (SCC)

•Ocular and periocular region, it can affect the:
(CCE)

A

Conjunctiva, Cornea, Eyelid skin

21
Q

The lesion in Squamous Cell Carcinoma might be:

A
  1. Nodular Squamous Cell Carcinoma
  2. Ulcerative Squamous Cell Carcinoma
22
Q

identify what lesion in squamous cell carcinoma:
hard, hyperkeratotic nodules, may develop crusting fissures.

A

Nodular Squamous Cell Carcinoma

23
Q

identify what lesion in squamous cell carcinoma:
- red base, borders sharply defined, induratedand elevated

A

Ulcerative Squamous Cell Carcinoma

24
Q

Give 5 risks in Squamous Cell Carcinoma

A

•Aging
•Longstanding ultraviolet radiation exposure
•Oil derivatives and arsenic exposure
•Cigarette smoke exposure
•Human Papilloma Virus infection (HPV)
•Human Immunodeficiency Virus infection (HIV)
•Xeroderma pigmentosum
•Actinic keratosis (AK)
•Squamous intraepithelial neoplasia (Bowen’s disease)
•Albinism
•Old burns
•Chronic ulcers
•Immunosuppression

25
Q

Give the 6 Symptoms of Squamous Cell Carcinoma

A

•Bleeding
•Pain
•Pruritus, irritation
•Enlarging lesion
•Ulceration
•Crusting lesion

26
Q

third most common eyelid malignancy

A

Meibomian Gland Carcinoma

27
Q

Meibomian Gland Carcinoma is also known as

A

Sebaceous Gland Carcinoma

28
Q

True or False: Meibomian Gland Carcinoma is not a rare aggressive tumor with 10% mortality

A

False; it is very rare

29
Q

Common location of Meibomian Gland Carcinoma

A

Upper Lid

30
Q

Meibomian Gland Carcinoma: ______% of eyelid malignancy

A

1-5.5%

31
Q

Meibomian Gland Carcinoma may arise from the:

A

Meibomian Gland
Gland of Zeiss
Glands associated with the Caruncle

32
Q

Which of the following statements describes the Melanoma the best:

a. not a rare form of eyelid tumor but the most lethal primary skin tumors
b. >1% of eyelid malignancies
c. These tumors are pigmented and are highly likely to metastasize, even if they’re small.
d. both b and c
e. none of the above

A

C; because melanoma is a rare form of tumor, <1% of eyelid malignancies

33
Q

The following are characteristics of Melanoma, except:

a. Often present as a dark
b. Variable pigmented nodule or plaque
c. Irregular notched borders
d. no exception

A

d

34
Q

Give 5 risks of Melanoma:

A

Sunlight exposure
Genetic predisposition
Environmental Mutagens
Aging
Treatment involves
Aggressive surgery (complete excision)
Incisional or excisional biopsy (diagnosis)
Potentially radiation

35
Q

It is a red to pink conjunctival tumor and a blue to purple eyelid tumor

A

Kaposi Sarcoma

36
Q

Vascular tumour commonly occurring in with AIDS

A

Kaposi Sarcoma

37
Q

Very Sensitive to radiotherapy

A

Kaposi Sarcoma

38
Q

Risk factors of Kaposi Sarcoma:

A

-HIV
-AIDS
-Immunocompromised patient
- Elderly Patient (slowly progressive)

39
Q

The lesion in Kaposi Sarcoma might be:

A

a. Early Kaposi Sarcoma
b. Advanced Kaposi Sarcoma

40
Q

Kaposi Sarcoma lesion that shows pink, red-violet lesion

A

Early Kaposi Sarcoma

41
Q

Kaposi Sarcoma lesion that might be ulcerate and bleed

A

Advanced Kaposi Sarcoma

42
Q

Diagnosis of Kaposi Sarcoma

A

-Skin and lymph nodes should be examined
-Blood should be tested for HIV, lymphocytes, and other opportunistic disease
-in patients with a history of Kaposi’s: incisional biopsy for presumptive diagnosis

43
Q

Treatment of Kaposi Sarcoma (Fill in the blanks)

Complete removal at biopsy (_______ ________ __________)

A

Small Kaposi’s Sarcoma

44
Q

Treatment of Kaposi Sarcoma (Fill in the blanks)

Incision Biopsy (________ and _______ _______)

A

Large and multifocal tumors

45
Q

Kaposi Sarcoma treatment:

A

-complete removal at biopsy (Small Kaposi’s Sarcoma)
-Incision Biopsy (Larger and multifocal tumors)
-chemotherapy
-radiation therapy
-avoid any treatment that would further suppress the patient’s immune system (HIV-AIDS related Kaposi sarcoma)

Ocular Disease (Eyelids) (3 decks)

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