Male Reproductive Drug Flashcards
5 Alpha Reductase Inhibitors
Testosterone Blockers
FINASTERIDE (proscar)
MOA
INDIC
AE
NURSING
MOA: block testosterone/shrink prostate
INDIC: BPH
AE: 1. reduce libido 2. hypotension
NURSING:
1.teach that symptom improve in 3-6months
2.woman wear gloves when handling this meds
**do not handle this meds while pregnant (category x)
**do not donate blood while on meds or dont have kids
Alpha-1 Adrenergic Blockers
TAMSULOSIN (Flomax)
MOA
INDIC
ROUTE
CONTRAINDICATIONS
DRUG-DRUG
AE
NURSING
**in class: trying to target PARASYMPATHETIC
MOA: blocks alpha 1 adrenergic receptor in
- smooth muscle of prostate
2.relaxes bladder neck and uretha allows urine to flow
INDIC: BPH
ROUTE: ER/ORAL
CON: Heart failure or CAD
DRUG-DRUG: antihypertensive drugs
AE:
1.tachycardia
2**hypotension
3.syncope
4.GI upset
5.sexual dysfunction
NURSING:
1.monitor for hypotension
2.do not crush / chew ER because it release formulation
3.monitor for symptom improvement
Penile Erectile Dysfunction
SILDENAFIL (Viagra)
MOA
INIDIC
ROUTE
CONTRAINDIC
DRUG-DRUG
AE
NURSING
MOA: cause prolonged smooth muscle relaxation
allowing flow of blood into corpus cavernosum and fascinating erection
INDIC: penile erectile dysfucntion
ROUTE: oral prior sexual stimulation
CONTRAINDIC: alot
DRUG-DRUG : no NITRATES (nitro tabs) within previous 24 hrs or alpha adrenergic blockers (tamsulosin)
AE:
1. headache
2.dizziness
3.hypotension
4.syncope
5.dizzy
NURSING: teach caution with nitrates
**grapefruit juice should not be taken because in 24-48 hrs because it alter enzymes
Penile Erectile Dysfunction
SILDENAFIL (Viagra)
MOA
INIDIC
ROUTE
CONTRAINDIC
DRUG-DRUG
AE
NURSING
MOA: cause prolonged smooth muscle relaxation
allowing flow of blood into corpus cavernosum and fascinating erection
INDIC: penile erectile dysfucntion
ROUTE: oral prior sexual stimulation
CONTRAINDIC: alot
DRUG-DRUG : no NITRATES (nitro tabs) within previous 24 hrs or alpha adrenergic blockers (tamsulosin)
AE:
1. headache
2.dizziness
3.hypotension
4.syncope
5.dizzy
NURSING: teach caution with nitrates
**grapefruit juice should not be taken because in 24-48 hrs because it alter enzymes
A patient is receiving finasteride (Proscar) for treatment of benign prostatic hyperplasia. The nurse will tell him that a possible effect of this medication is:
a. alopecia.
b. increased hair growth.
c. urinary retention.
d. increased prostate size.
b. increased hair growth.
Finasteride is given to reduce prostate size in men with benign prostatic hyperplasia. It has been noted that men taking this medication experience increased hair growth.
During the administration of finasteride (Proscar), the nurse must remember which important precaution?
a. It must be taken on an empty stomach.
b. It must not be handled by pregnant women.
c. It is given by deep intramuscular injection to avoid tissue irritation.
d. The patient needs to be warned that alopecia is a common adverse effect.
b. It must not be handled by pregnant women.
Finasteride must not be handled by pregnant women because of its teratogenic effects. It is taken orally and without regard to meals.
A 73-year-old male patient is in the clinic for a yearly physical and is asking for a prescription for sildenafil (Viagra). He has listed on his health history that he is taking a nitrate for angina. The nurse is aware that which problem may occur if sildenafil is taken with a nitrate?
a. Significant increase in pulse rate
b. Significant decrease in blood pressure
c. Increased risk of bleeding
d. Reduced effectiveness of the sildenafil
b. Significant decrease in blood pressure
In patients with pre-existing cardiovascular disease, especially those on nitrates, erectile dysfunction drugs such as sildenafil lower blood pressure substantially, potentially leading to more serious adverse events.
. A patient will be receiving testosterone cypionate (Depo-Testosterone) 400 mg intramuscularly every 4 weeks. The medication is available in a 200-mg/mL strength. Identify how many milliliters will the nurse draw up for each injection. _______
ANS: 2 mL
200 mg:1 mL :: 400 mg:x mL.
(200 × x) = (1 × 400); 200x = 400; x = 2 mL.
KARCH
A patient has high blood pressure and penile erectile dysfunction. He asks the nurse if he could try SILDENAFIL after seeing an advertisement on television. What medications, if taken by the patient, would the nurse recognize as increasing the risk associated with taking tadalafil?
A) Beta-blockers
B) Angiotensin-converting enzyme (ACE) inhibitors
C) Alpha-adrenergic blockers
D) Calcium channel blockers
C) Alpha-adrenergic blockers
Serious drops in blood pressure, leading to potentially fatal myocardial infarction or cerebrovascular event, have been reported when Cialis is combined with alpha-adrenergic blockers.
A patient will begin taking sildenafil (Viagra) for penile erectile dysfunction (ED). What is the nurse’s priority teaching point about this drug?
A) He will have an erection exactly 1 hour after taking the drug.
B) The drug should not be taken with a penile implant or any anatomic penile obstruction.
C) Avoid drinking grapefruit juice for 2 days before and after taking the drug.
D) It is important to know the cause of ED because sildenafil does not treat all causes.
C) Avoid drinking grapefruit juice for 2 days before and after taking the drug.
Patients who are using sildenafil need to be advised to avoid drinking grapefruit juice while using the drug. Grapefruit juice can cause a decrease in the metabolism of the PDE5 inhibitor, leading to increased serum levels and a risk of toxicity. They need to know that it takes 48 hours for grapefruit juice to be processed by the body, so they need to avoid it for several days before and after taking the drug.
A patient has been prescribed sildenafil citrate. What should the nurse teach the patient about this medication?
A) Take the medication with a glass of grapefruit juice.
B) The drug should be taken 1 hour before attempting intercourse.
C) Facial flushing or headache should be reported to the physician immediately.
D) A dose exceeding 80 mg will result in a change of vision, making everything appear blue.
B) The drug should be taken 1 hour before attempting intercourse.
A 55-year-old man presents at the clinic complaining of erectile dysfunction. The patient has a history of diabetes mellitus. The physician orders tadalafil (Cialis) to be taken 1 hour before sexual intercourse. The nurse reviews the patient’s history before instructing the patient on the use of this medication. What disorder (or condition) would contraindicate the use of tadalafil (Cialis)?
A) Cataracts
B) Penile implant
C) Hypotension
D) Lung cancer
B) Penile implant
Patients with a penile implant should not take tadalafil.
For what reason might the nurse administer sildenafil to a woman?
A) Pulmonary arterial hypertension
B) Sexual dysfunction
C) Breast cancer
D) Endometriosis
A) Pulmonary arterial hypertension
A 68-year-old male patient tells the nurse that he has been unable to get an erection for the past 6 months and he guesses his sex life is over. The provider orders diagnostic testing to determine whether sildenafil (Viagra) is appropriate for the patient. What is the most correct nursing diagnosis for this patient?
A) Sexual dysfunction
B) Disturbed body image
C) Ineffective sexuality
pattern
D) Disturbed tactile sensory perception
A) Sexual dysfunction
The patient is experiencing sexual dysfunction so that would be the most appropriate nursing diagnosis.
The 22-year-old patient tells the nurse he doesn’t have trouble obtaining and maintaining an erection but wonders if taking Viagra would improve the sexual experience anyway. What is the nurse’s best response?
A) The only thing Viagra does is improve blood flow to the penis to make it erect.
B) Viagra improves stamina and sensation, making the sexual experience better.
C) Viagra has its greatest effect if both the man and woman take it at the same time.
D) Viagra does nothing to improve the sexual experience
A) The only thing Viagra does is improve blood flow to the penis to make it erect.
Viagra improves blood flow into the penis and that is its only effect. It does not improve stamina or sensation.
