Male Reproduction Introduction Flashcards

1
Q

Basic Male Anatomy

A

Seminiferous tubule, Rete testis, Efferent dustules, Epididymis, Vas deferens/Ductus deferens
Spermatic cord, Abdominal activity, Prostatic urethra, Seminal vesicles, Penis

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2
Q

A capsule of Dense CT

A

Tunica Albuginea

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3
Q

split testis into>200 lobules

A

Septa

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4
Q

Circular structures

A

Intertitial cells and Seminiferous tubules

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5
Q

Steroid-secreting cells

A

Leydig cells

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6
Q

Function of Leydig cells

A

Secrete testosterone

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7
Q

Primary male hormone responsible for: sex differentiation producing male sex characteristics
spermatogenesis
fertility

A

Testosterone

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8
Q

HUGE amount of SER (eosinophilic)

A

steroid-secreting cells

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9
Q

In adults, testoterone secretion is crucial for

A

Spermatogenesis and secondary sex characteristics

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10
Q

Stratified epithelium with Sertoli cells

where the maturation of sperm (spermatogenesis) occurs with sertoli cells

A

Seminiferous tubules

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11
Q

Near the base of tubule large, lightly stained, triangular nuclei

A

Sertoli cell

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12
Q

Sertoli cell functions

A

provide physical support and organization for developing sperm linked together-tight junction-ZONULA OCCLUDENS-BTB (BLOOD TESTIS BARRIER)

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13
Q

blood testis barrier funx

A

Isolates haploid antigenic cells from the systemic immune system

Sertoli cells secrete ANDROGEN BINDING PROTEIN (ABP)

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14
Q

requires high concentrations of local testosterone

A

Spermatogenesis

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15
Q

Spermatogenesis

A

Maturation: begins near the Basal lamina-moves toward the ST Lumen

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16
Q

Exist between the Basal lamina of ST and Sertoli cells located OUTSIDE the BTB

A

Spermatogonia

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17
Q

As they mature, the B spermatogonia will undergo mitosis and become

A

Primary spermatocytes

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18
Q

Which exists INSIDE the BTB; between the Seroli cells and ST Lumen

Undergoing meiosis

stringy appearance due to chromosomes lining up

A

primary spermatocytes

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19
Q

Primary spermatocytes are undergoing meiosis to become

A

Haploid germ cells aka Spermatids

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20
Q

As they Mature: they go through many morphologic changes during spermiogenesis

A

Spermatids

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21
Q

Spermatids four phases

A

Golgi phase, Cap phase, Acrosome phase, Maturation phase

22
Q

Maturation of spermatids

A

physically connected to seroli cell membranes via special junctions

23
Q

Final phase of spermatid

A

spermatids released from SC into ST lumen as Mature sperm cells aka spermatozoa

24
Q

Non-motile
Travel through ST in Sertoli cell fluid towards the epididymis

A

Spermatozoa

25
Q

dense CT of mediastinum

A

ST

26
Q

Dense CT of Mediastinum

Irregular spaces lined with cuboidal epithelium

lead to excurrent ducts between ST and epididymis

A

Rete testis

27
Q

Extratesticular;located between rete testis and epididymis

Saw-tooth epithelium of ciliated columnar and non ciliated cuboidal

A

Efferent ductules

28
Q

Functions of efferent ductules

A

Absorbs fluids secreted by sertoli cells

“Alternating groups” border

29
Q

Numerous section of epididymis- circular structures throughout

A

Epididymus duct, epididymis duct epithelium, epithelium with stereocilia

30
Q

More even border than efferent ductules

A

epididymis duct

31
Q

Tall pseudostratified columnar epithelium

A

epididymis duct epithelium

32
Q

long modified microvilli

contain core of actin filaments

A

Epithelium with stereocilia

33
Q

Epithelium
with stereocilia function

A

absorption

34
Q

Clumps in the lumen – which have mature in the epididymis gaining motility and ability to fertilize an oocyte

Smooth muscle surrounding the lining epithelium; undergoes rhythmic peristaltic construction that moves the sperm along the duct

A

Spermatozoa

35
Q

stores majority of spermatozoa in adult males; VIABLE FOR WEEKS. But once it enters the vagina they can only survive for 3-4 days.

A

epididymis

36
Q

The direct continuation of epididymis

A

Vas deferens

37
Q

firm structure of vas deferens

A

I. thick coat of smooth muscle (blue line) – inner longitudinal layer (green), middle circular layer (red), outer longitudinal layer (black)
II. Mucosa appears folded (artifact of fixation) – due to contraction of thick muscular wall
III. Vas deferens epithelium: Pseudostratified columnar epithelium with stereocilia

38
Q

Accessory gland with irregular lumen
Highly folded mucosa = A defining characteristic of Seminal vesicle
Note: larger in younger males with high androgen levels

A

Seminal vesicle

39
Q

SV Mucosa

A

Columnar/Cuboidal Epithelium and Thin Lamina Propria

40
Q

Seminal vesicle FUNCTIONS

A

Secretes seminal fluid; FRUCTOSE and CITRATE-RICH
Sperm’s main nutrient source
Note: prostate and bulbourethral gland also secretes seminal fluids

41
Q

Aged SV: mucosal layer ATROPHIED
Due to lower systemic androgen levels

Atrophy
decrease in size – cell, organ, or other tissue

A

Seminal vesicle (aged)

42
Q

Largest male accessory sex gland
Secrete alkaline fluid (PH 7.3) for seminal fluid
Prostate glandular epithelium: Simple cuboidal/columnar epithelium
Prostatic secretions contents:
PSA
Prostatic Acid
Phosphatase
Fibrinolysin
Citric Acid

A

Prostate gland

43
Q

Precipitated prostate secretions in prostatic alveoli
Appear as circular structures in the secretory alveoli
Distinguishing feature of the prostate

A

Prostatic concretions

44
Q

A section of the prostate where the urethra begins
Urethra– crescent-shaped structure
Vas deferens
Seminal vesicles
prostate

A

Prostatic urethra

45
Q

Urothelium/transitional epithelium – umbrella / dome-shaped cells

A

Prostatic urethra

46
Q

Structure of Penis

A

Corpora cavernosa (red) – dorsal side of the penis; bilateral
Corpus spongiosum (blue) with Urethra (green)

Dense fibroelastic tissue = tunica albuginea. (yellow) = surrounds all three structures

47
Q

Filled with irregular venous spaces lined with vascular endothelium
Venous rbcs separated by: Trabeculla of Fibromuscular Connective Tx

A

Corpus cavernosum

48
Q

Helicine arteries (black arrow) : coiled with flaccid penis and extended with erect penis
Oddly shaped with thick walls

A

Penis

49
Q

helicine arteries dilate – blood fills the venous
spaces of cavernosum and spongiosum

A

Erection

50
Q

Muscles compress veins – decreases the venous return – allowing
the erection to be maintained.

A

The pressure of erect penis, Ischiocavernosus and bulbospongiosus