MALE REPRO | GOLJAN Flashcards

1
Q

cause of congenital megaloureter?

A

Hirschsprung disease

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2
Q

smooth cysts in the ureter lumen?

A

ureteritis cystica

predispose to bladder adenocarcinoma

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3
Q

ureteritis cystica predisposes too?

A

adenocarcinoma

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4
Q

MC complication of retroperitoneal fibrosis?

A

hydronephrosis

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5
Q

MC cancer of ureter?

A

transitional cell carcinoma (TCC)

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6
Q

exstrophy of bladder associated w?

A

epispadias and bladder adenocarcinoma

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7
Q

MCC of bladder adenocarcinoma?

A

urachal cyst remnants

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8
Q

Bowen disease HPV?

A

16

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9
Q

CIS of penis

A
  1. Bowen disease
  2. Erythroplasia of Queyrat
  3. Bowenoid papulosis
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10
Q

CIS of penis

multiple reddish brown papules

A

Bowenoid papulosis

*only one with no predisposition to SCC

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11
Q

CIS of penis

leukoplakia on shaft of penis

A

Bowen disease

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12
Q

CIS of penis

erythroplakia on mucosal surface of glans

A

Queyrat

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13
Q

MC cancer of penis

A

SCC

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14
Q

SCC penis HPV

A

16,18

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15
Q

epididymitis >35 years old

A

E.coli

Pseudomonas aeruginosa

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16
Q

absent cremasteric reflex

A

torsion of the testicle

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17
Q

which organism mainly affects the testis?

A

syphillis

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18
Q

MC paratesticular tumor

A

adenomatoid tumor

pole of the epididymis

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19
Q

types of testicular tumors

A

germ cell

sex cord-stromal

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20
Q

bulky tumor- no hemorrhage or necrosis

A

seminoma

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21
Q

bulky tumor- with hemorrhage and necrosis

A

embryonal carcinoma

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22
Q

tumor- hCG

A

choriocarcinoma

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23
Q

tumor- AFP

A

yolk sac

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24
Q

teratocarcinoma

A

teratoma + embryonal carcinoma

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25
what are the testicular tumors(germ cell)
1. seminoma 2. spermatocytic seminoma 2. embryonal carcinoma 3. yolk sac 4. choriocarcinoma 5. teratoma
26
what are the testicular tumors(sex cord)
1. leydig cell 2. sertoli cell 3. malignant lymphoma
27
what do patients w/ Leydig tumors present w?
adults-gynecomastia | kids-precocious puberty
28
key histological feature of leydig cells tumors?
intracytoplasmic reinke crystals
29
major causes of priapism
venous thrombosis of corpora cavernosa | sickle cell disease
30
seminoma-age group
mid 30s
31
which testicular tumor resembles placenta tissue?
choriocarcinoma
32
seminoma-serum marker
hCG
33
embryonal carcinoma-serum marker
hCG or AFP
34
purulent urethral discharge | gram stains fails to reveal any organisms
chlamydia trachomatis
35
35 year old painless enlargement of testes increased serum hCG
seminoma
36
serum marker of osteoblast activity seen w prostatic adenocarcinoma metastasis
alkaline phosphatase
37
causes of retroperitoneal fibrosis
1. idiopathic 2. ergot alkaloids associated with MIGRAINES 3. other sclerosing conditions ( sclerosing cholangitis, reidel thyroidits 4. retroperitoneal malignant lymphoma
38
what is the median umbilical ligament
fibrous urachus connecting the bladder to the umbilicus
39
what occurs if lumen of urachus remains open?
urine from bladder gets drained by umbilicus
40
*how to differentiate SCHISTOSOMA HAEMATOBIUM egg for SCHISTOSOMA MANSONI egg*
HAEMATOBIUM has terminal spine | MANSONI has lateral spine
41
what drug produces hemorrhagic cystitis treated w? what organism can cause it?
cyclophosphamide MESNA adenovirus*
42
MCC of sepsis/UTI in hospital
indwelling catheter
43
tx for schistosoma haematobium
praziquantel
44
MC uropathogen
e. coli
45
tx for e.coli cystitis
double strength TMP-SMX
46
neutrophils in urine + NO culture growth
C. trachomatis renal TB acute tubulointerstitial nephritis
47
purpose of nitrites in urine
bacteria in urine change nitrates to nitrites | IF + then bacterial infections
48
purpose of leukocyte esterase in urine
indicates presence of WBC
49
what is seen in urinalysis of sterile pyuria
+ neutrophils + leukocyte esterase - nitrites - culture
50
chronic e.coli infection of bladder leads to
malacoplakia
51
defective phagosomes that cannot degrade bacterial products
Michaelis-Gutmann bodies
52
what is seen in MALACOPLAKIA
many yellow, raised mucosal plaques | Michaelis Gutmann bodies
53
MC bladder cancer
TCC
54
SCC of bladder
S. haematobium
55
TCC causes
MC- smoking cigs cyclophosphamide nitrosamines ( beer ) arsenic
56
how are helminth eggs killed?
type 2 HSR involving eosinophils
57
infections of urethra
venereal - C. trachomatis + N. gonorrhoeae | non-venereal - E. coli
58
C. trachomatis can cause what syndrome
Reiter syndrome 1. conjunctivitis 2. urethritis 3. HLA_B27 arthritis
59
pathogenesis of hypospadias
faulty closure of urethral folds
60
pathogenesis of epispadias
defect in genital tubercle
61
MC GU disorder in male children
cryptorchidism
62
* causes of EPIDIDYMITIS*
E.coli + P.aeruginosa >35 y/o C.trachomatis + N.gonorrhea <35 y/o TB**
63
clinical features of EPIDIDYMITIS
unilateral scrotal pain and extends into spermatic cord | swelling + tenderness
64
elevation of scrotum decreases pain AKA
prehn sign
65
tx for epididymitis
35 ciprofloxacin extended release
66
MCC of left sided scrotal enlargement
varicocele
67
pathogenesis of varicocele
left spermatic vein drains into left renal vein | due to BLOCKAGE
68
where does right spermatic vein drain into
IVC
69
cause of right sided varicocele
retroperitoneal fibrosis + IVC thrombosis
70
MCC of scrotal enlargement in children
hydrocele
71
clinical features of TORSION of testicle
absent cremasteric reflex* | sudden onset of testicular pain
72
nonspecific cancer enzyme
lactate dehydrogenase