MALE REPRO | GOLJAN Flashcards
cause of congenital megaloureter?
Hirschsprung disease
smooth cysts in the ureter lumen?
ureteritis cystica
predispose to bladder adenocarcinoma
ureteritis cystica predisposes too?
adenocarcinoma
MC complication of retroperitoneal fibrosis?
hydronephrosis
MC cancer of ureter?
transitional cell carcinoma (TCC)
exstrophy of bladder associated w?
epispadias and bladder adenocarcinoma
MCC of bladder adenocarcinoma?
urachal cyst remnants
Bowen disease HPV?
16
CIS of penis
- Bowen disease
- Erythroplasia of Queyrat
- Bowenoid papulosis
CIS of penis
multiple reddish brown papules
Bowenoid papulosis
*only one with no predisposition to SCC
CIS of penis
leukoplakia on shaft of penis
Bowen disease
CIS of penis
erythroplakia on mucosal surface of glans
Queyrat
MC cancer of penis
SCC
SCC penis HPV
16,18
epididymitis >35 years old
E.coli
Pseudomonas aeruginosa
absent cremasteric reflex
torsion of the testicle
which organism mainly affects the testis?
syphillis
MC paratesticular tumor
adenomatoid tumor
pole of the epididymis
types of testicular tumors
germ cell
sex cord-stromal
bulky tumor- no hemorrhage or necrosis
seminoma
bulky tumor- with hemorrhage and necrosis
embryonal carcinoma
tumor- hCG
choriocarcinoma
tumor- AFP
yolk sac
teratocarcinoma
teratoma + embryonal carcinoma
what are the testicular tumors(germ cell)
- seminoma
- spermatocytic seminoma
- embryonal carcinoma
- yolk sac
- choriocarcinoma
- teratoma
what are the testicular tumors(sex cord)
- leydig cell
- sertoli cell
- malignant lymphoma
what do patients w/ Leydig tumors present w?
adults-gynecomastia
kids-precocious puberty
key histological feature of leydig cells tumors?
intracytoplasmic reinke crystals
major causes of priapism
venous thrombosis of corpora cavernosa
sickle cell disease
seminoma-age group
mid 30s
which testicular tumor resembles placenta tissue?
choriocarcinoma
seminoma-serum marker
hCG
embryonal carcinoma-serum marker
hCG or AFP
purulent urethral discharge
gram stains fails to reveal any organisms
chlamydia trachomatis
35 year old
painless enlargement of testes
increased serum hCG
seminoma
serum marker of osteoblast activity seen w prostatic adenocarcinoma metastasis
alkaline phosphatase
causes of retroperitoneal fibrosis
- idiopathic
- ergot alkaloids associated with MIGRAINES
- other sclerosing conditions ( sclerosing cholangitis, reidel thyroidits
- retroperitoneal malignant lymphoma
what is the median umbilical ligament
fibrous urachus connecting the bladder to the umbilicus
what occurs if lumen of urachus remains open?
urine from bladder gets drained by umbilicus
how to differentiate SCHISTOSOMA HAEMATOBIUM egg for SCHISTOSOMA MANSONI egg
HAEMATOBIUM has terminal spine
MANSONI has lateral spine
what drug produces hemorrhagic cystitis
treated w?
what organism can cause it?
cyclophosphamide
MESNA
adenovirus*
MCC of sepsis/UTI in hospital
indwelling catheter
tx for schistosoma haematobium
praziquantel
MC uropathogen
e. coli
tx for e.coli cystitis
double strength TMP-SMX
neutrophils in urine + NO culture growth
C. trachomatis
renal TB
acute tubulointerstitial nephritis
purpose of nitrites in urine
bacteria in urine change nitrates to nitrites
IF + then bacterial infections
purpose of leukocyte esterase in urine
indicates presence of WBC
what is seen in urinalysis of sterile pyuria
+ neutrophils
+ leukocyte esterase
- nitrites
- culture
chronic e.coli infection of bladder leads to
malacoplakia
defective phagosomes that cannot degrade bacterial products
Michaelis-Gutmann bodies
what is seen in MALACOPLAKIA
many yellow, raised mucosal plaques
Michaelis Gutmann bodies
MC bladder cancer
TCC
SCC of bladder
S. haematobium
TCC causes
MC- smoking cigs
cyclophosphamide
nitrosamines ( beer )
arsenic
how are helminth eggs killed?
type 2 HSR involving eosinophils
infections of urethra
venereal - C. trachomatis + N. gonorrhoeae
non-venereal - E. coli
C. trachomatis can cause what syndrome
Reiter syndrome
- conjunctivitis
- urethritis
- HLA_B27 arthritis
pathogenesis of hypospadias
faulty closure of urethral folds
pathogenesis of epispadias
defect in genital tubercle
MC GU disorder in male children
cryptorchidism
- causes of EPIDIDYMITIS*
E.coli + P.aeruginosa >35 y/o
C.trachomatis + N.gonorrhea <35 y/o
TB**
clinical features of EPIDIDYMITIS
unilateral scrotal pain and extends into spermatic cord
swelling + tenderness
elevation of scrotum decreases pain AKA
prehn sign
tx for epididymitis
35 ciprofloxacin extended release
MCC of left sided scrotal enlargement
varicocele
pathogenesis of varicocele
left spermatic vein drains into left renal vein
due to BLOCKAGE
where does right spermatic vein drain into
IVC
cause of right sided varicocele
retroperitoneal fibrosis + IVC thrombosis
MCC of scrotal enlargement in children
hydrocele
clinical features of TORSION of testicle
absent cremasteric reflex*
sudden onset of testicular pain
nonspecific cancer enzyme
lactate dehydrogenase