Male Hypogonadisim Flashcards
• Kallmann syndrome is a form of hypogonadotropic hypogonadism
With either incompletely (hyposmia) or completely (anosmia).
develop eunuchoidism.
Weight loss or systemic illness in male patients can cause
Another form of secondary hypogonadism, hypothalamic dysfunction.
The most common congenital cause of primary testicular failure is
Klinefelter’s syndrome,
small, firm testes measuring less than 2 cm
Azoospermia;
Eunuchoid skeletal proportions
myotonic dystrophy
Primary gonadal failure i
Bilateral anorchia is differentiated from cryptorchidism by
An HCG stimulation test
Patients with cryptorchidism have an increase in serum testosterone level after an injection of HCG,whereas patients with bilateral anorchia do not.
Defects in Androgen Action
of testicular feminization, a form of male pseudohermaphroditism. (Androgen Insensitivity Syndrome)
The labial-scrotal folds fail to fuse =short vagina
phenotypic females.
uterus is absent due to Anti-Müllerian duct hormone
Partial forms of androgen insensitivity
who lack the 5α-reductase enzyme
SHBG may increase with
smoking
excessive coffee consumption
age,
disease processes such as hepatitis and hyperthyroidism.
Diagnosis requires a low serum testosterone level on
at least two separate occasions in conjunction with at least one clinical symptom.
Diagnosis
The most common cause of primary amenorrhea is
The second most common cause is
Gonadal dysgenesis, which is found in Turner syndrome.
müllerian agenesis, a congenital malformation resulting in lack of uterine development and vaginal hypoplasia.