Male Hormones

Question 2

If morning cortisol is elevated; it could indicate:

Answer 2

infection, nocturnal hypoglycemia and or increased risk for a cardiovascular event

Question 3

DHEA is the major precursors of what

Answer 3

androstenedione, testosterone and estrogens

Question 4

cholesterol is metabolized into pregnenolone which is concerted to either _______ or _______ both of which are converted to testosterone

Answer 4

androstenediol or androstenedione

Question 5

testosterone is primarily produced by the action of ___ on the ____ cells of the _____ although small amounts of testosterone can be secreted by the adrenal glands

Answer 5

LH, Leydig cells, Testis

Question 6

The Leydig cells of the testis produce what

Answer 6

testosterone

Question 7

what can testosterone be converted into

Answer 7

estradiol or dihydrotestosterone

Question 8

Estradiol of dihydrotestosterone come from what

Answer 8

testosterone

Question 9

5-alpha reductase is the enzyme that converts what to what

Answer 9

testosterone to DHT (5a-dihydro-testosterone)

Question 10

what enzyme cnonverts: testosterone to DHT (5a-dihydro-testosterone)

Answer 10

5-alpha reductase

Question 11

aromatase is the enzyme that converts what to what

Answer 11

testosterone to estradiol

Question 12

what enzyme converts testosterone to estradiol

Answer 12

aromatase

Question 13

what have high levels of testosterone been assocaited with

Answer 13

high cholesterol, prostate problems, atherosclerosis and aggression.

Question 14

salivary vs serum testosterone testing

Answer 14

97-98% of plasma testosterone is bound to sex hormone-binding globulin (SHBG) and only 2-3% is free testosterone.
-total serum is useful to determine whether there is normal response of the Leydig cells to FHS and LH, saliva is the test to give true levels of the bioavailability of testosterone.

Question 15

DHT is made how

Answer 15

from testosterone with the enzyme 5-alpha reductase

Question 16

Increased production of DHT has been shown to cause:

Answer 16

prostate growth
male pattern baldness

Question 17

what drugs are used to inhibit 5-alpha reductase in cases of prostate hyperplasia?

Answer 17

Propecia and Proscar

Question 18

what two herbs function to limit 5-alpha reductase and when would you use them

Answer 18

-saw palmetto and Licorice (Glycyrrhiza Glabra)
-in cases of increased DHT (5a-dihydro-testosterone) to prevent prostate hyperplasia

Question 19

what can you use to treat prostate hyperplasia

Answer 19

-saw palmetto
-Licorice (Glycyrrhiza Glabra)

Question 20

Androstenedione is a weak androgen and a direct precursor to what

Answer 20

testosterone and estrone

Question 21

in men, excessive androstenedione results in

Answer 21

excessive estrone production

Question 22

in men after 30, there is a 1-2% decrease in production of testosterone from the testes. In hope of being converted to testosterone, the adrenals begin making more what

Answer 22

adrenals start making more androstenedione hoping it will get converted to testosterone

Question 23

when here is an increase of androstenedione without increasing levels of testosterone this represents a what

Answer 23

biochemical glitch

Question 24

what is the biochemical glitch with testosterone

Answer 24

when there is an increase in androstenedione without an increase in testosterone

Question 25

when there is increased androstenedione without an increase in testosterone what natural agents are recommended

Answer 25

Vitamin E
Lipoic Acid
Co-Enzyme Q10
Zin

Question 26

Vitamin E, Lipoic Acid, Co-Enzyme Q10 and Zinc are recommended for males when

Answer 26

there is an increase in androstenedione without an increase in testosterone

Question 27

progesterone is largely made from ______ in the ______ of males

Answer 27

pregnenolone in the adrenal glands

Question 28

where is progesterone made from in males

Answer 28

adrenal glands

Question 29

what is calming to the body and activates the GABA chloride channel to help the body shut down for rest and recovery

Answer 29

progesterone

Question 30

what acts to limit the conversion of testosterone to DHT

Answer 30

progesterone

Question 31

what is an antagonist to the effects of estrogens in the bodies of males

Answer 31

progesterone

Question 32

in men almost all estrone is converted from what

Answer 32

androstenedione

Question 33

where is estrone stored

Answer 33

in adipose tissue. the more adipose tissue, the higher the level of estrone

Question 34

excess estrone in males can lead to

Answer 34

weight gain (storage of fat) and prostate enlargement

Question 35

if low testoerone is reported than teh following should be ruled out

Answer 35

1. conversion problem of androstenedione to testosterone
2. Depressed DHEA/pregnenolone steal
3. Depressed levels of androstenedione

Question 36

what herbs are good to increase testosterone when all other pathway problems are ruled out

Answer 36

-50-100mg/day oral capsule testosterone
-stinging nettle
-Damiana (Tunera Diffusa)
-Sarsaparilla

Question 37

what are good ways to decrease testosterone levels

Answer 37

-saw palmetto berries (anti-androgenic by inhibiting formation of DHT di-hydrotestoerone)
-Chaste tree berries
-Pygeum: decreases DHT synthesis and testosterone uptake by the prostate

Question 38

what helps with the estrogen metabolism and detoxification of steroids

Answer 38

DIM (diindolymethane) found in brassica plants

Question 39

what are part of the brassica genus and what do they help with

Answer 39

broccoli, cabbage, brusssel sprouts, cauliflower, kale
estrogen metabolism and detox of steroids

Question 40

testosterone concentration has been noted to drop as much as ___% from morning to evening.

Answer 40

50%

Question 41

medication conditions commonly responsible for lowering testosterone levels

Answer 41

DM
Liver disease
Hemochromatosis
Obesity (esp. abdominal fat)

Question 42

medications found to lower testosterone levels include

Answer 42

Ketoconazole
Cimetidine
Glucocorticoids
Smoking and C. alcohol use